rewire.itbenchmarks
Dataset subset

Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)

Dataset subset reported in GEARS primary supplement, Table6. Exact split manifest remains unextracted; source-table identity is retained.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-09-29-06401fd5b220 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

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  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

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  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
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  • score semantics: verification is missing
  • recipe pinned: verification is missing
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Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

4 evaluations · 8 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: CPAProtocol: GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.354 ± 0.049 mse
squared_expression_units_unreported · lower

Uncertainty: type: unreported; reported spread: 0.049; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CPA on GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row CPA, column MSE
Configuration: CPAProtocol: GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.440 ± 0.036 pearson_delta_expression
correlation · higher

Uncertainty: type: unreported; reported spread: 0.036; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CPA on GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row CPA, column Pearson DE
Configuration: CPA + KGProtocol: GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.333 ± 0.046 mse
squared_expression_units_unreported · lower

Uncertainty: type: unreported; reported spread: 0.046; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CPA + KG on GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row CPA + KG, column MSE
Configuration: CPA + KGProtocol: GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.504 ± 0.029 pearson_delta_expression
correlation · higher

Uncertainty: type: unreported; reported spread: 0.029; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CPA + KG on GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row CPA + KG, column Pearson DE
Configuration: GEARSProtocol: GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.216 ± 0.053 mse
squared_expression_units_unreported · lower

Uncertainty: type: unreported; reported spread: 0.053; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

GEARS on GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row GEARS, column MSE
Configuration: GEARSProtocol: GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.556 ± 0.030 pearson_delta_expression
correlation · higher

Uncertainty: type: unreported; reported spread: 0.030; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

GEARS on GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row GEARS, column Pearson DE
Configuration: No PerturbProtocol: GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.551 ± 0.029 mse
squared_expression_units_unreported · lower

Uncertainty: type: unreported; reported spread: 0.029; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

No Perturb on GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row No Perturb, column MSE
Configuration: No PerturbProtocol: GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE
Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
0.004 ± 0.006 pearson_delta_expression
correlation · higher

Uncertainty: type: unreported; reported spread: 0.006; note: Printed ± spread; SD/SE/CI type not established by inspected table caption.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

No Perturb on GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE

Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted.

Aggregation: Not reported

GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row No Perturb, column Pearson DE

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

Subset and evaluation context

This record describes a particular subset or cohort used in an evaluation. Its results do not describe the full dataset.

Evidence

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Evidence table

Inspect claims, sources and review details

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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

2 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
description
Dataset subset reported in GEARS primary supplement, Table6. Exact split manifest remains unextracted; source-table identity is retained.
Context-only references
GEARS primary supplement, Table6

Original source ↗

No field-specific location recorded

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

name
Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)
Context-only references
GEARS primary supplement, Table6

Original source ↗

No field-specific location recorded

Version: 10.1038/s41587-023-01905-6 publisher supplement
Retrieved: 2026-09-23T11:36:52.243763+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 1daaeb10f072577a3e420a796cd7e29e88ea9462639de7332ae91b2fe86b3b24

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

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Release 2026-09-29-06401fd5b220 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: gears-2023-supp-table6-dataset-norman-et-al-2019-perturbation-data-used-in-gears-supplementary-table6

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cells-spatial-multiomics
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version: unreported; url: unextracted
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