No Perturb | configuration

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Evaluations and results

1 evaluation · 2 results. Different protocols are not a single leaderboard.

Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)

Sorted by MSE (lower is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Protocol and dataset	MSE	Pearson delta (all genes; mean over perturbations)
No PerturbEvaluation	GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE	0.551 ± 0.029	Not reported
No PerturbEvaluation	GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE	Not reported	0.004 ± 0.006

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: No Perturb	Protocol: GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)	0.551 ± 0.029 MSE unit-unreported · lower Uncertainty: ± 0.029 (type not stated). Printed ± spread; SD/SE/CI type not established by inspected table caption. Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source No Perturb on GEARS Norman2019 CPA-control comparison MSE: Norman2019 perturbation-response MSE Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted. Aggregation: Not reported GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row No Perturb, column MSE
Configuration: No Perturb	Protocol: GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE Dataset subset: Norman et al.2019 perturbation data used in GEARS Supplementary Table6 (GEARS Norman2019 CPA-control comparison split)	0.004 ± 0.006 Pearson delta (all genes; mean over perturbations) unitless · higher Uncertainty: ± 0.006 (type not stated). Printed ± spread; SD/SE/CI type not established by inspected table caption. Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source No Perturb on GEARS Norman2019 CPA-control comparison Pearson DE: Norman2019 perturbation-response Pearson DE Predict post-perturbation expression on Norman2019. MSE compares predicted and true expression; Pearson DE compares predicted versus true change over unperturbed controls (Supplementary Table1). Exact Table6 scoring gene subset and split manifest remain unextracted. Aggregation: Not reported GEARS primary supplement, Table6 · Supplementary Table6, printed p34 / PDF p35, row No Perturb, column Pearson DE

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Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

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GEARS primary supplement, Table6 · Original source · 10.1038/s41587-023-01905-6 publisher supplement

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Technical metadata and extraction receipts

Stable ID: gears-2023-supp-table6-method-no-perturb

areas: single-cell
source locator: Supplementary Table6, printed p34 / PDF p35, row No Perturb; Supplementary Note5.
missing metadata: checkpoint revision: reason: unreported; parameters: reason: unextracted
provenance note: No Perturb configuration as evaluated in GEARS Table6.

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