rewirebio.iobenchmarks
Dataset subset

TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)

TraitGym fine-mapped UK Biobank GWAS variants (PIP above 0.9) with matched controls (PIP below 0.01), after removing positions overlapping AVI training or validation variants.

Evaluation results

15 evaluations · 15 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: AVI six-model ensemble (AlphaGenome Atlas v1)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
0.283 AUPRC (AVI baseline row, TraitGym Complex column)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI AVI Model (Baseline) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Baseline', row 'AVI Model', column 'TraitGym Complex'
Configuration: AVI ablation 'All except AlphaGenome' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
-27.7% AUPRC relative difference (ablation 'All except AlphaGenome' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI All except AlphaGenome (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'All except AlphaGenome', column 'TraitGym Complex'
Configuration: AVI ablation 'AlphaGenome' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
-17.3% AUPRC relative difference (ablation 'AlphaGenome' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI AlphaGenome (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'AlphaGenome', column 'TraitGym Complex'
Configuration: AVI ablation 'AlphaMissense' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
0.67% AUPRC relative difference (ablation 'AlphaMissense' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI AlphaMissense (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'AlphaMissense', column 'TraitGym Complex'
Configuration: AVI ablation 'Cactus' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
-6.64% AUPRC relative difference (ablation 'Cactus' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI Cactus (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'Cactus', column 'TraitGym Complex'
Configuration: AVI ablation 'Consequence' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
0.28% AUPRC relative difference (ablation 'Consequence' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI Consequence (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'Consequence', column 'TraitGym Complex'
Configuration: AVI ablation 'Conservation' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
-26.3% AUPRC relative difference (ablation 'Conservation' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI Conservation (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'Conservation', column 'TraitGym Complex'
Configuration: AVI ablation 'Indel Type' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
-2.19% AUPRC relative difference (ablation 'Indel Type' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI Indel Type (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'Indel Type', column 'TraitGym Complex'
Configuration: AVI ablation 'PhastCons' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
-2.15% AUPRC relative difference (ablation 'PhastCons' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI PhastCons (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'PhastCons', column 'TraitGym Complex'
Configuration: AVI ablation 'Protein' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
1.13% AUPRC relative difference (ablation 'Protein' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI Protein (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'Protein', column 'TraitGym Complex'
Configuration: AVI ablation 'Splicing Removed Only' (Retrained, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
-2.61% AUPRC relative difference (ablation 'Splicing Removed Only' (Retrained) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI Splicing Removed Only (Retrained) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Retrained', row 'Splicing Removed Only', column 'TraitGym Complex'
Configuration: AVI ablation '+ No Indel Type' (Features Set to Zero, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
0% AUPRC relative difference (ablation '+ No Indel Type (second occurrence, below 'No AlphaMissense Indel Features')' (Features Set to Zero) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI + No Indel Type (Features Set to Zero) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Features Set to Zero', row '+ No Indel Type (second occurrence, below 'No AlphaMissense Indel Features')', column 'TraitGym Complex'
Configuration: AVI ablation 'No AlphaMissense Indel Features' (Features Set to Zero, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
0% AUPRC relative difference (ablation 'No AlphaMissense Indel Features' (Features Set to Zero) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI No AlphaMissense Indel Features (Features Set to Zero) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Features Set to Zero', row 'No AlphaMissense Indel Features', column 'TraitGym Complex'
Configuration: AVI ablation '+ No Indel Type' (Features Set to Zero, AlphaGenome Atlas Table S2)Protocol: AVI feature ablation, TraitGym Complex column, AUPRC (AlphaGenome Atlas Table S2)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
0% AUPRC relative difference (ablation '+ No Indel Type' (Features Set to Zero) relative to the AVI baseline row, TraitGym Complex column)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AVI + No Indel Type (Features Set to Zero) on TraitGym Complex (AlphaGenome Atlas Table S2)

ag-atlas-20261019-protocol-table-s2-traitgym-complex

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Table S2 (page 70), section 'Features Set to Zero', row '+ No Indel Type', column 'TraitGym Complex'
Configuration: AVI six-model ensemble (AlphaGenome Atlas v1)Protocol: TraitGym fine-mapped GWAS variants, AUPRC after AVI filtering (AlphaGenome Atlas)
Dataset subset: TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
0.28 AUPRC (TraitGym fine-mapped GWAS (Complex))
unitless · higher

Uncertainty: Not reported by the source: Fig. 2B draws 95% bootstrap intervals (100 bootstraps) without printing them.

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

avi on TraitGym fine-mapped GWAS (Complex) (AlphaGenome Atlas Fig. 2B)

ag-atlas-20261019-protocol-traitgym-complex-auprc

Aggregation: Not reported

AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Results 'State-of-the-art interpretable genome-wide variant prioritization with AVI' paragraph 1 (page 5), citing Fig. 2B: 'TraitGym Complex, AUPRC 0.28 vs. 0.27'

Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-11-02-a7f03c9e55a5 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

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  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
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Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

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  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
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Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Subset and evaluation context

This record describes a particular subset or cohort used in an evaluation. Its results do not describe the full dataset.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

8 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statementOriginal source and locationReview and provenance
Limitations
1 values
  • TraitGym Complex chromosomes 2, 5, 11, 14, 17, 20, 22 and X were AVI validation data (Methods 'Data Split'); whether Fig. 2B excludes them is not stated.
Context-only references
AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026)

Original source ↗

Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)

Version: medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Retrieved: 2026-10-19T12:19:03Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.limitations

Source artifact SHA-256: b32d1539005ca4ea31c3dcef49b834424b1d8b5da4ce6b9fc3e1f942d39fc453

Hash scope: SHA-256 of one retrieval of the medRxiv PDF. A second retrieval at 2026-10-19T12:30:54Z had the same length (15,415,633 bytes) and the same SHA-256.

Inspected artifact

Original printed counts
+409/-3686
Context-only references
AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026)

Original source ↗

Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)

Version: medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Retrieved: 2026-10-19T12:19:03Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.original_printed_counts

Source artifact SHA-256: b32d1539005ca4ea31c3dcef49b834424b1d8b5da4ce6b9fc3e1f942d39fc453

Hash scope: SHA-256 of one retrieval of the medRxiv PDF. A second retrieval at 2026-10-19T12:30:54Z had the same length (15,415,633 bytes) and the same SHA-256.

Inspected artifact

Positive count
409
Context-only references
AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026)

Original source ↗

Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)

Version: medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Retrieved: 2026-10-19T12:19:03Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.positive_count

Source artifact SHA-256: b32d1539005ca4ea31c3dcef49b834424b1d8b5da4ce6b9fc3e1f942d39fc453

Hash scope: SHA-256 of one retrieval of the medRxiv PDF. A second retrieval at 2026-10-19T12:30:54Z had the same length (15,415,633 bytes) and the same SHA-256.

Inspected artifact

Source location
Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)
Context-only references
AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026)

Original source ↗

Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)

Version: medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Retrieved: 2026-10-19T12:19:03Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: b32d1539005ca4ea31c3dcef49b834424b1d8b5da4ce6b9fc3e1f942d39fc453

Hash scope: SHA-256 of one retrieval of the medRxiv PDF. A second retrieval at 2026-10-19T12:30:54Z had the same length (15,415,633 bytes) and the same SHA-256.

Inspected artifact

Test count
4095
Context-only references
AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026)

Original source ↗

Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)

Version: medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Retrieved: 2026-10-19T12:19:03Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.test_count

Source artifact SHA-256: b32d1539005ca4ea31c3dcef49b834424b1d8b5da4ce6b9fc3e1f942d39fc453

Hash scope: SHA-256 of one retrieval of the medRxiv PDF. A second retrieval at 2026-10-19T12:30:54Z had the same length (15,415,633 bytes) and the same SHA-256.

Inspected artifact

Description
TraitGym fine-mapped UK Biobank GWAS variants (PIP above 0.9) with matched controls (PIP below 0.01), after removing positions overlapping AVI training or validation variants.
Context-only references
AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026)

Original source ↗

Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)

Version: medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Retrieved: 2026-10-19T12:19:03Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: b32d1539005ca4ea31c3dcef49b834424b1d8b5da4ce6b9fc3e1f942d39fc453

Hash scope: SHA-256 of one retrieval of the medRxiv PDF. A second retrieval at 2026-10-19T12:30:54Z had the same length (15,415,633 bytes) and the same SHA-256.

Inspected artifact

Relationship: same data as
lit-genomics-20261011-traitgym-data-complex-traits-matched-9
Context-only references
AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026)

Original source ↗

Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)

Version: medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Retrieved: 2026-10-19T12:19:03Z

not individually reviewed

No individual claim review recorded

Audit details

Field: links:same_data_as:lit-genomics-20261011-traitgym-data-complex-traits-matched-9

Source artifact SHA-256: b32d1539005ca4ea31c3dcef49b834424b1d8b5da4ce6b9fc3e1f942d39fc453

Hash scope: SHA-256 of one retrieval of the medRxiv PDF. A second retrieval at 2026-10-19T12:30:54Z had the same length (15,415,633 bytes) and the same SHA-256.

Inspected artifact

Name
TraitGym Complex traits after AVI positional filtering (AlphaGenome Atlas)
Context-only references
AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026)

Original source ↗

Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)

Version: medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Retrieved: 2026-10-19T12:19:03Z

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: b32d1539005ca4ea31c3dcef49b834424b1d8b5da4ce6b9fc3e1f942d39fc453

Hash scope: SHA-256 of one retrieval of the medRxiv PDF. A second retrieval at 2026-10-19T12:30:54Z had the same length (15,415,633 bytes) and the same SHA-256.

Inspected artifact

Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: ag-atlas-20261019-subset-traitgym-complex

areas
dna-genomes
contexts
research
positive count
409
test count
4095
original printed counts
+409/-3686
source locator
Fig. 2B panel header 'Fine-mapped GWAS (TraitGym) (+409/-3686)'; Methods 'TraitGym Phenotypic Association' (page 28)
limitations
TraitGym Complex chromosomes 2, 5, 11, 14, 17, 20, 22 and X were AVI validation data (Methods 'Data Split'); whether Fig. 2B excludes them is not stated.
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