| Configuration: GENA-LM 110M, efficient inference implementation (Saadat and Fellay 2026) | Protocol: Pseudo-perplexity agreement between reference and efficient implementations (Saadat and Fellay 2026 Figure 1) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | r = 1.00 Pearson (Agreement of per-sequence pseudo-perplexity between the reference and the efficient implementation, 50 synthetic sequences of length 1000) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGENA-LM 110M efficient implementation, pseudo-perplexity agreement with the reference saadat-fellay-20261015-protocol-pseudo-perplexity-agreement Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Figure 1 (page 4, raster), panel 'GENA-LM 110M', legend text 'r = 1.00' |
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| Configuration: GENA-LM 110M, training with FlashAttention and checkpointing (Saadat and Fellay 2026) | Protocol: Training peak GPU memory under progressive optimizations, sequence length 1000, batch size 16 (Saadat and Fellay 2026 Figure 3) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | 1.18 Peak memory (Training, sequence length 1000, batch size 16, stage + Checkpointing (FlashAttention and activation checkpointing)) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGENA-LM 110M training peak memory, stage + Checkpointing saadat-fellay-20261015-protocol-training-peak-memory Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Section 3.3 'ZeRO offload' paragraph (page 6): '(e.g., GENA-LM 110M increases from 1.18 to 2.49 GB)'; stage + Checkpointing (FlashAttention and activation checkpointing) of Figure 3 |
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| Configuration: GENA-LM 110M, training with FlashAttention, checkpointing and ZeRO-2 offload (Saadat and Fellay 2026) | Protocol: Training peak GPU memory under progressive optimizations, sequence length 1000, batch size 16 (Saadat and Fellay 2026 Figure 3) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | 2.49 Peak memory (Training, sequence length 1000, batch size 16, stage + DeepSpeed (FlashAttention, checkpointing and ZeRO Stage-2 CPU offload)) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGENA-LM 110M training peak memory, stage + DeepSpeed saadat-fellay-20261015-protocol-training-peak-memory Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Section 3.3 'ZeRO offload' paragraph (page 6): '(e.g., GENA-LM 110M increases from 1.18 to 2.49 GB)'; stage + DeepSpeed (FlashAttention, checkpointing and ZeRO Stage-2 CPU offload) of Figure 3 |
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| Configuration: GENA-LM 336M, efficient inference implementation (Saadat and Fellay 2026) | Protocol: Pseudo-perplexity agreement between reference and efficient implementations (Saadat and Fellay 2026 Figure 1) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | r = 1.00 Pearson (Agreement of per-sequence pseudo-perplexity between the reference and the efficient implementation, 50 synthetic sequences of length 1000) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGENA-LM 336M efficient implementation, pseudo-perplexity agreement with the reference saadat-fellay-20261015-protocol-pseudo-perplexity-agreement Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Figure 1 (page 4, raster), panel 'GENA-LM 336M', legend text 'r = 1.00' |
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| Configuration: NT 2.5B, efficient inference implementation (Saadat and Fellay 2026) | Protocol: Pseudo-perplexity agreement between reference and efficient implementations (Saadat and Fellay 2026 Figure 1) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | r = 0.98 Pearson (Agreement of per-sequence pseudo-perplexity between the reference and the efficient implementation, 50 synthetic sequences of length 1000) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNT 2.5B efficient implementation, pseudo-perplexity agreement with the reference saadat-fellay-20261015-protocol-pseudo-perplexity-agreement Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Figure 1 (page 4, raster), panel 'NT 2.5B', legend text 'r = 0.98' |
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| Configuration: NT 2.5B, 4-bit weights for embedding inference (Saadat and Fellay 2026) | Protocol: Peak memory under 8-bit and 4-bit quantization relative to BF16 (Saadat and Fellay 2026 Figure 5) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | 5.6 Peak memory (Embedding inference with 4-bit weights; the paper calls it parameter memory in Section 2.4 and peak memory in Figure 5) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNT 2.5B 4-bit inference memory saadat-fellay-20261015-protocol-quantization-peak-memory Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Section 3.5 'Memory' paragraph (page 7): 'For NT 2.5B, memory decreases from 6.7 GB (BF16) to 5.6 GB (4-bit).' |
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| Configuration: NT 2.5B, BF16 weights for embedding inference (Saadat and Fellay 2026) | Protocol: Peak memory under 8-bit and 4-bit quantization relative to BF16 (Saadat and Fellay 2026 Figure 5) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | 6.7 Peak memory (Embedding inference with BF16 weights; the paper calls it parameter memory in Section 2.4 and peak memory in Figure 5) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNT 2.5B BF16 inference memory saadat-fellay-20261015-protocol-quantization-peak-memory Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Section 3.5 'Memory' paragraph (page 7): 'For NT 2.5B, memory decreases from 6.7 GB (BF16) to 5.6 GB (4-bit).' |
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| Configuration: NT 2.5B, training with FlashAttention and checkpointing (Saadat and Fellay 2026) | Protocol: Training peak GPU memory under progressive optimizations, sequence length 1000, batch size 16 (Saadat and Fellay 2026 Figure 3) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | 33.9 Peak memory (Training, sequence length 1000, batch size 16, stage + Checkpointing (FlashAttention and activation checkpointing)) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNT 2.5B training peak memory, stage + Checkpointing saadat-fellay-20261015-protocol-training-peak-memory Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Section 3.3 'ZeRO offload' paragraph (page 6): 'the NT 2.5B checkpoint (33.88 → 11.49 GB)'; stage + Checkpointing (FlashAttention and activation checkpointing) of Figure 3 |
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| Configuration: NT 2.5B, training with FlashAttention, checkpointing and ZeRO-2 offload (Saadat and Fellay 2026) | Protocol: Training peak GPU memory under progressive optimizations, sequence length 1000, batch size 16 (Saadat and Fellay 2026 Figure 3) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | 11.5 Peak memory (Training, sequence length 1000, batch size 16, stage + DeepSpeed (FlashAttention, checkpointing and ZeRO Stage-2 CPU offload)) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNT 2.5B training peak memory, stage + DeepSpeed saadat-fellay-20261015-protocol-training-peak-memory Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Section 3.3 'ZeRO offload' paragraph (page 6): 'the NT 2.5B checkpoint (33.88 → 11.49 GB)'; stage + DeepSpeed (FlashAttention, checkpointing and ZeRO Stage-2 CPU offload) of Figure 3 |
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| Configuration: NT 500M, efficient inference implementation (Saadat and Fellay 2026) | Protocol: Pseudo-perplexity agreement between reference and efficient implementations (Saadat and Fellay 2026 Figure 1) Dataset: Synthetic uniform random DNA sequences, seed 42 (Saadat and Fellay 2026) | r = 1.00 Pearson (Agreement of per-sequence pseudo-perplexity between the reference and the efficient implementation, 50 synthetic sequences of length 1000) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNT 500M efficient implementation, pseudo-perplexity agreement with the reference saadat-fellay-20261015-protocol-pseudo-perplexity-agreement Aggregation: Not reported Optimizing genomic language models for efficient training, fine-tuning, and inference (Saadat and Fellay, ICLR 2026 workshop) · Figure 1 (page 4, raster), panel 'NT 500M', legend text 'r = 1.00' |
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