rewirebio.iobenchmarks
Dataset

10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)

Input reads for the compute benchmark.

Evaluation results

1 evaluation · 7 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: Sentieon DNAscope Hybrid on Azure HB120rs v3 (Hu et al. 2026)Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2)
Dataset: 10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)
18.8 Runtime (alignment stage; 10x PacBio HiFi plus 35x Illumina)
minute · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNAscope Hybrid compute benchmark on Azure (Hu et al. 2026)

model-execution-20261011-protocol-hu2026-dnascope-azure-compute

Aggregation: Not reported

A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Alignment (min)', column 'DNAscope Hybrid'
Configuration: Sentieon DNAscope Hybrid on Azure HB120rs v3 (Hu et al. 2026)Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2)
Dataset: 10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)
172 CPU time (total, FASTQ to VCF; 10x PacBio HiFi plus 35x Illumina)
hour · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNAscope Hybrid compute benchmark on Azure (Hu et al. 2026)

model-execution-20261011-protocol-hu2026-dnascope-azure-compute

Aggregation: Not reported

A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Core-hours', column 'DNAscope Hybrid'
Configuration: Sentieon DNAscope Hybrid on Azure HB120rs v3 (Hu et al. 2026)Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2)
Dataset: 10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)
5.2 Compute cost (Azure on-demand price, FASTQ to VCF; 10x PacBio HiFi plus 35x Illumina)
us-dollar · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNAscope Hybrid compute benchmark on Azure (Hu et al. 2026)

model-execution-20261011-protocol-hu2026-dnascope-azure-compute

Aggregation: Not reported

A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'On-demand ($)', column 'DNAscope Hybrid'
Configuration: Sentieon DNAscope Hybrid on Azure HB120rs v3 (Hu et al. 2026)Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2)
Dataset: 10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)
2 Runtime (preprocessing stage; 10x PacBio HiFi plus 35x Illumina)
minute · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNAscope Hybrid compute benchmark on Azure (Hu et al. 2026)

model-execution-20261011-protocol-hu2026-dnascope-azure-compute

Aggregation: Not reported

A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Preprocessing (min)', column 'DNAscope Hybrid'
Configuration: Sentieon DNAscope Hybrid on Azure HB120rs v3 (Hu et al. 2026)Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2)
Dataset: 10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)
0.52 Compute cost (Azure spot price, FASTQ to VCF; 10x PacBio HiFi plus 35x Illumina)
us-dollar · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNAscope Hybrid compute benchmark on Azure (Hu et al. 2026)

model-execution-20261011-protocol-hu2026-dnascope-azure-compute

Aggregation: Not reported

A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Spot ($)', column 'DNAscope Hybrid'
Configuration: Sentieon DNAscope Hybrid on Azure HB120rs v3 (Hu et al. 2026)Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2)
Dataset: 10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)
85.8 Runtime (total, FASTQ to VCF; 10x PacBio HiFi plus 35x Illumina)
minute · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNAscope Hybrid compute benchmark on Azure (Hu et al. 2026)

model-execution-20261011-protocol-hu2026-dnascope-azure-compute

Aggregation: Not reported

A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Total runtime (min)', column 'DNAscope Hybrid'
Configuration: Sentieon DNAscope Hybrid on Azure HB120rs v3 (Hu et al. 2026)Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2)
Dataset: 10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)
65 Runtime (variant calling stage; 10x PacBio HiFi plus 35x Illumina)
minute · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNAscope Hybrid compute benchmark on Azure (Hu et al. 2026)

model-execution-20261011-protocol-hu2026-dnascope-azure-compute

Aggregation: Not reported

A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Variant calling (min)', column 'DNAscope Hybrid'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • A pinned run recipe exists: not yet verified
  • Compute requirements are estimated: not yet verified

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
  • Overlap with training data is checked: not yet verified

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Dataset and evaluation context

A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

5 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Population
10x PacBio HiFi plus 35x Illumina whole-genome reads; sample not named for Table 2
Context-only references
A novel and accelerated method for integrated alignment and variant calling from short and long reads

Original source ↗

Table 2 row 'Dataset'; Methods 'Datasets used in this study'

Version: Frontiers in Bioinformatics 5:1691056, published 2026-01-05; PMC12813096 full-text XML
Retrieved: 2026-10-11T21:42:46Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.population

Source artifact SHA-256: b138dd8976f01b4ff50f72669dea3a7062f564a9cb359417aad0dc72a8b6c859

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
Table 2 row 'Dataset'; Methods 'Datasets used in this study'
Context-only references
A novel and accelerated method for integrated alignment and variant calling from short and long reads

Original source ↗

Table 2 row 'Dataset'; Methods 'Datasets used in this study'

Version: Frontiers in Bioinformatics 5:1691056, published 2026-01-05; PMC12813096 full-text XML
Retrieved: 2026-10-11T21:42:46Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: b138dd8976f01b4ff50f72669dea3a7062f564a9cb359417aad0dc72a8b6c859

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Split
One value; number of runs not stated
Context-only references
A novel and accelerated method for integrated alignment and variant calling from short and long reads

Original source ↗

Table 2 row 'Dataset'; Methods 'Datasets used in this study'

Version: Frontiers in Bioinformatics 5:1691056, published 2026-01-05; PMC12813096 full-text XML
Retrieved: 2026-10-11T21:42:46Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.split

Source artifact SHA-256: b138dd8976f01b4ff50f72669dea3a7062f564a9cb359417aad0dc72a8b6c859

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
Input reads for the compute benchmark.
Context-only references
A novel and accelerated method for integrated alignment and variant calling from short and long reads

Original source ↗

Table 2 row 'Dataset'; Methods 'Datasets used in this study'

Version: Frontiers in Bioinformatics 5:1691056, published 2026-01-05; PMC12813096 full-text XML
Retrieved: 2026-10-11T21:42:46Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: b138dd8976f01b4ff50f72669dea3a7062f564a9cb359417aad0dc72a8b6c859

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Name
10x PacBio HiFi plus 35x Illumina WGS input for DNAscope Hybrid (Hu et al. 2026 Table 2)
Context-only references
A novel and accelerated method for integrated alignment and variant calling from short and long reads

Original source ↗

Table 2 row 'Dataset'; Methods 'Datasets used in this study'

Version: Frontiers in Bioinformatics 5:1691056, published 2026-01-05; PMC12813096 full-text XML
Retrieved: 2026-10-11T21:42:46Z

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: b138dd8976f01b4ff50f72669dea3a7062f564a9cb359417aad0dc72a8b6c859

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: model-execution-20261011-data-hu2026-dnascope-hybrid

areas
dna-genomes
contexts
clinical_research
population
10x PacBio HiFi plus 35x Illumina whole-genome reads; sample not named for Table 2
split
One value; number of runs not stated
source locator
Table 2 row 'Dataset'; Methods 'Datasets used in this study'
missing metadata
accession: reason: unreported; note: Sample not named for Table 2; version: reason: unreported
Related records

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