Dataset

Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)

Real plasma cohort used by Sun et al. 2024 to test deconvolution-based disease detection.

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Release 2026-10-09-8cc1db47c7f9 · Evidence verified: Not verified

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Evaluation results

5 evaluations · 25 results. Different protocols are not a single leaderboard.

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Tested model or methodProtocolDatasetEvaluation setupMetricEvidence origin

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: CelFEER (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.85 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFEER deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', I6; row 'Colon cancer'; column 'CelFEER' under 'AUC values'
Configuration: CelFEER (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.91 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFEER deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', I9; row 'Gastric cancer'; column 'CelFEER' under 'AUC values'
Configuration: CelFEER (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.87 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFEER deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', I5; row 'Liver cancer (cfMethyl-Seq)'; column 'CelFEER' under 'AUC values'
Configuration: CelFEER (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.8 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFEER deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', I7; row 'LUAD'; column 'CelFEER' under 'AUC values'
Configuration: CelFEER (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.78 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFEER deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', I8; row 'LUSC'; column 'CelFEER' under 'AUC values'
Configuration: CelFiE (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.91 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFiE deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', J6; row 'Colon cancer'; column 'CelFiE' under 'AUC values'
Configuration: CelFiE (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.93 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFiE deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', J9; row 'Gastric cancer'; column 'CelFiE' under 'AUC values'
Configuration: CelFiE (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.82 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFiE deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', J5; row 'Liver cancer (cfMethyl-Seq)'; column 'CelFiE' under 'AUC values'
Configuration: CelFiE (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.83 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFiE deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', J7; row 'LUAD'; column 'CelFiE' under 'AUC values'
Configuration: CelFiE (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.83 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source CelFiE deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', J8; row 'LUSC'; column 'CelFiE' under 'AUC values'
Configuration: cfNOMe (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.82 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source cfNOMe deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', K6; row 'Colon cancer'; column 'cfNOMe' under 'AUC values'
Configuration: cfNOMe (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.87 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source cfNOMe deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', K9; row 'Gastric cancer'; column 'cfNOMe' under 'AUC values'
Configuration: cfNOMe (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.87 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source cfNOMe deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', K5; row 'Liver cancer (cfMethyl-Seq)'; column 'cfNOMe' under 'AUC values'
Configuration: cfNOMe (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.85 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source cfNOMe deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', K7; row 'LUAD'; column 'cfNOMe' under 'AUC values'
Configuration: cfNOMe (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.84 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source cfNOMe deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', K8; row 'LUSC'; column 'cfNOMe' under 'AUC values'
Configuration: MethAtlas (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.82 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source MethAtlas deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', L6; row 'Colon cancer'; column 'MethAtlas' under 'AUC values'
Configuration: MethAtlas (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.86 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source MethAtlas deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', L9; row 'Gastric cancer'; column 'MethAtlas' under 'AUC values'
Configuration: MethAtlas (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.84 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source MethAtlas deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', L5; row 'Liver cancer (cfMethyl-Seq)'; column 'MethAtlas' under 'AUC values'
Configuration: MethAtlas (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.77 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source MethAtlas deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', L7; row 'LUAD'; column 'MethAtlas' under 'AUC values'
Configuration: MethAtlas (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.78 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source MethAtlas deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', L8; row 'LUSC'; column 'MethAtlas' under 'AUC values'
Configuration: UXM (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.81 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source UXM deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', M6; row 'Colon cancer'; column 'UXM' under 'AUC values'
Configuration: UXM (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.87 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source UXM deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', M9; row 'Gastric cancer'; column 'UXM' under 'AUC values'
Configuration: UXM (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.83 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source UXM deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', M5; row 'Liver cancer (cfMethyl-Seq)'; column 'UXM' under 'AUC values'
Configuration: UXM (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.78 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source UXM deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', M7; row 'LUAD'; column 'UXM' under 'AUC values'
Configuration: UXM (Sun et al. 2024 benchmark)	Protocol: Sun et al. 2024 five-cancer detection from deconvolved plasma cfMethyl-Seq (ROC-AUC per cancer type) Dataset: Plasma cfMethyl-Seq, 225 cancer patients and 193 healthy individuals (EGAD00001009003)	0.72 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source UXM deconvolution, disease detection AUC (cfMethyl-Seq cohort) ctdnameth-20261009-protocol-sun2024-cfmethyl-detection-auc Aggregation: Not reported Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA; Sun et al. 2024, Additional file 1 (Tables S1-S8) · Sun Additional file 1, sheet 'Table S7 ', M8; row 'LUSC'; column 'UXM' under 'AUC values'

Source checking is not independent reproduction. Release 2026-10-09-8cc1db47c7f9.

Dataset and evaluation context

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Evidence

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Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

11 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-09-8cc1db47c7f9
Property and statement	Original source and location	Review and provenance
attributes.access Controlled access through EGA Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.access` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.accession EGAD00001009003 Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.accession` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.assay Plasma cfMethyl-Seq; TrimGalore v0.6.10, Bismark v0.24.2 alignment to hg38, deduplication, wgbstools pat files Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.assay` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.negatives 193 Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.negatives` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.population 225 cancer patients (67 lung adenocarcinoma, 41 lung squamous cell carcinoma, 30 liver, 54 colon, 33 stomach) and 193 healthy individuals Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.population` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.positives 225 Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.positives` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.scope_note Same source study as amp-data-cfmethyl-408 (Stackpole et al. 2022), but the counts differ: that record has 217 cancers and 191 non-cancers passing QC. The two are not linked as the same data. Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.scope_note` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.source_locator Sun et al. 2024, Methods 'Data collection and processing' (P30) Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
attributes.version EGA EGAD00001009003 (Stackpole et al. 2022, Nat Commun) as reprocessed by Sun et al. 2024 Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.version` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
description Real plasma cohort used by Sun et al. 2024 to test deconvolution-based disease detection. Context-only references	Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA Original source ↗ Sun et al. 2024, Methods 'Data collection and processing' (P30) Version: Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML Retrieved: 2026-10-09T19:58:16Z	not individually reviewed No individual claim review recorded Audit details Field: `description` Source artifact SHA-256: `ce2ac8671cfddf088b33efb150ca50354181de81ca6bfb181dd5bf387c6714e8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact

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Release 2026-10-09-8cc1db47c7f9 · Record review: source checked

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Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA · Original source · Genome Biology 25:318, published 2024-12-19; PMC11660681.1 full-text XML

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Stable ID: ctdnameth-20261009-data-sun2024-cfmethyl-seq-plasma

areas: dna-genomes
contexts: clinical_research
version: EGA EGAD00001009003 (Stackpole et al. 2022, Nat Commun) as reprocessed by Sun et al. 2024
accession: EGAD00001009003
assay: Plasma cfMethyl-Seq; TrimGalore v0.6.10, Bismark v0.24.2 alignment to hg38, deduplication, wgbstools pat files
population: 225 cancer patients (67 lung adenocarcinoma, 41 lung squamous cell carcinoma, 30 liver, 54 colon, 33 stomach) and 193 healthy individuals
positives: 225
negatives: 193
access: Controlled access through EGA
scope note: Same source study as amp-data-cfmethyl-408 (Stackpole et al. 2022), but the counts differ: that record has 217 cancers and 191 non-cancers passing QC. The two are not linked as the same data.
source locator: Sun et al. 2024, Methods 'Data collection and processing' (P30)

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