rewirebio.iobenchmarks
Dataset

DELFI 2019 internally cross-validated cancer detection cohort

DELFI 2019 internally cross-validated cancer detection cohort; bounded primary-source candidate.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-10-07-1448159e6a81 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • recipe pinned: verification is missing
  • resource estimate: verification is missing

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 1 result. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: DELFI 2019 internally cross-validated cancer detection tested configurationProtocol: DELFI 2019 internally cross-validated cancer detection protocol
Dataset: DELFI 2019 internally cross-validated cancer detection cohort
73% sensitivity_at_reported_98_percent_specificity
percent · higher

Uncertainty: 95% CI 67%–79%; sensitivity intervals from 2,000 bootstrap replicates

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DELFI 2019 internally cross-validated cancer detection

amp-20261007-ctdna-fragmentomics-protocol

Aggregation: Not reported

Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252 · PMC6774252 Table 1 T1 Cancer row / 98% specificity columns; Results P15; Methods P34; Extended Data Fig. 7 F11.

Source checking is not independent reproduction. Release 2026-10-07-1448159e6a81.

Dataset and evaluation context

A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

5 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-07-1448159e6a81
Property and statementOriginal source and locationReview and provenance
attributes.population
208 patients with seven cancer types and 215 healthy individuals used for classifier; broader study abstract 236 cancers/245 healthy is not classifier denominator.
Context-only references
Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252

Original source ↗

No field-specific location recorded

Version: Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252
Retrieved: 2026-10-07T12:24:27.091080+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.population

Source artifact SHA-256: 192730a334f4752575543fb6bd9d13faa84eb27e939d918363cfe633c0358322

Hash scope: Hash scope not separately documented; inspect source record

Format: curator_factual_receipt

attributes.split
10-fold cross-validation repeated 10 times; feature selection and model estimation on training folds only
Context-only references
Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252

Original source ↗

No field-specific location recorded

Version: Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252
Retrieved: 2026-10-07T12:24:27.091080+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.split

Source artifact SHA-256: 192730a334f4752575543fb6bd9d13faa84eb27e939d918363cfe633c0358322

Hash scope: Hash scope not separately documented; inspect source record

Format: curator_factual_receipt

attributes.version
Not reported
Context-only references
Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252

Original source ↗

No field-specific location recorded

Version: Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252
Retrieved: 2026-10-07T12:24:27.091080+00:00

missing or unspecified

No individual claim review recorded

Audit details

Field: attributes.version

Source artifact SHA-256: 192730a334f4752575543fb6bd9d13faa84eb27e939d918363cfe633c0358322

Hash scope: Hash scope not separately documented; inspect source record

Format: curator_factual_receipt

description
DELFI 2019 internally cross-validated cancer detection cohort; bounded primary-source candidate.
Context-only references
Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252

Original source ↗

No field-specific location recorded

Version: Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252
Retrieved: 2026-10-07T12:24:27.091080+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 192730a334f4752575543fb6bd9d13faa84eb27e939d918363cfe633c0358322

Hash scope: Hash scope not separately documented; inspect source record

Format: curator_factual_receipt

name
DELFI 2019 internally cross-validated cancer detection cohort
Context-only references
Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252

Original source ↗

No field-specific location recorded

Version: Cristiano et al., Nature 570, 385–389 (2019), author manuscript PMC6774252
Retrieved: 2026-10-07T12:24:27.091080+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 192730a334f4752575543fb6bd9d13faa84eb27e939d918363cfe633c0358322

Hash scope: Hash scope not separately documented; inspect source record

Format: curator_factual_receipt

Sources and history

View linked audit checks and correction history

Release 2026-10-07-1448159e6a81 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: amp-20261007-ctdna-fragmentomics-dataset

areas
dna-genomes
method types
supervised_machine_learning
tasks
cancer_detection
missing metadata
version: No immutable dataset version extracted
population
208 patients with seven cancer types and 215 healthy individuals used for classifier; broader study abstract 236 cancers/245 healthy is not classifier denominator.
split
10-fold cross-validation repeated 10 times; feature selection and model estimation on training folds only
version
Not reported
Related records

Suggest a correction