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OHE ESM-1v

Supervised fitness predictor evaluated by the ProteinGym authors. The leading term is the input representation the paper's model type column gives.

4 evaluations · 8 results

Overview

Supervised fitness predictor evaluated by the ProteinGym authors. The leading term is the input representation the paper's model type column gives.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

4 evaluations · 8 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: OHE ESM-1vTask: ProteinGym SUP-SUB-MSE-AVG: Supervised substitutions, average over splits, MSE
Dataset subset: ProteinGym substitution DMS assays (ProteinGym split)
0.897 mse
error · lower

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OHE ESM-1v on ProteinGym SUP-SUB-MSE-AVG: Supervised substitutions, average over splits, MSE

Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits.

Aggregation: Not reported

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(ESM-1v), column(Supervised substitutions, average over splits, MSE)
Configuration: OHE ESM-1vTask: ProteinGym SUP-SUB-MSE-CONTIG: Supervised substitutions, contiguous split, MSE
Dataset subset: ProteinGym substitution DMS assays (ProteinGym split)
0.977 mse
error · lower

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OHE ESM-1v on ProteinGym SUP-SUB-MSE-CONTIG: Supervised substitutions, contiguous split, MSE

Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits.

Aggregation: Not reported

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(ESM-1v), column(Supervised substitutions, contiguous split, MSE)
Configuration: OHE ESM-1vTask: ProteinGym SUP-SUB-MSE-MOD: Supervised substitutions, modulo split, MSE
Dataset subset: ProteinGym substitution DMS assays (ProteinGym split)
0.949 mse
error · lower

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OHE ESM-1v on ProteinGym SUP-SUB-MSE-MOD: Supervised substitutions, modulo split, MSE

Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits.

Aggregation: Not reported

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(ESM-1v), column(Supervised substitutions, modulo split, MSE)
Configuration: OHE ESM-1vTask: ProteinGym SUP-SUB-MSE-RAND: Supervised substitutions, random split, MSE
Dataset subset: ProteinGym substitution DMS assays (ProteinGym split)
0.764 mse
error · lower

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OHE ESM-1v on ProteinGym SUP-SUB-MSE-RAND: Supervised substitutions, random split, MSE

Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits.

Aggregation: Not reported

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(ESM-1v), column(Supervised substitutions, random split, MSE)
Configuration: OHE ESM-1vTask: ProteinGym SUP-SUB-SPEARMAN-AVG: Supervised substitutions, average over splits, Spearman
Dataset subset: ProteinGym substitution DMS assays (ProteinGym split)
0.417 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OHE ESM-1v on ProteinGym SUP-SUB-SPEARMAN-AVG: Supervised substitutions, average over splits, Spearman

Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits.

Aggregation: Not reported

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(ESM-1v), column(Supervised substitutions, average over splits, Spearman)
Configuration: OHE ESM-1vTask: ProteinGym SUP-SUB-SPEARMAN-CONTIG: Supervised substitutions, contiguous split, Spearman
Dataset subset: ProteinGym substitution DMS assays (ProteinGym split)
0.367 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OHE ESM-1v on ProteinGym SUP-SUB-SPEARMAN-CONTIG: Supervised substitutions, contiguous split, Spearman

Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits.

Aggregation: Not reported

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(ESM-1v), column(Supervised substitutions, contiguous split, Spearman)
Configuration: OHE ESM-1vTask: ProteinGym SUP-SUB-SPEARMAN-MOD: Supervised substitutions, modulo split, Spearman
Dataset subset: ProteinGym substitution DMS assays (ProteinGym split)
0.368 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OHE ESM-1v on ProteinGym SUP-SUB-SPEARMAN-MOD: Supervised substitutions, modulo split, Spearman

Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits.

Aggregation: Not reported

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(ESM-1v), column(Supervised substitutions, modulo split, Spearman)
Configuration: OHE ESM-1vTask: ProteinGym SUP-SUB-SPEARMAN-RAND: Supervised substitutions, random split, Spearman
Dataset subset: ProteinGym substitution DMS assays (ProteinGym split)
0.514 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OHE ESM-1v on ProteinGym SUP-SUB-SPEARMAN-RAND: Supervised substitutions, random split, Spearman

Supervised fitness prediction under three cross-validation schemes: contiguous, modulo and random splits.

Aggregation: Not reported

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 3, row(ESM-1v), column(Supervised substitutions, random split, Spearman)

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

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How it works, versions and access

Underlying model: ESM-1v. Results on this page belong to this configuration and its evaluated settings.

Strengths, limitations and unresolved questions

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
Relationship: uses model
discovery-model-esm-1v
Individual claims
ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design

Original source ↗

Section 4.2 Supervised benchmarks, Baselines; Table 3

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.522924+00:00

source checked

automated source review · 2026-09-23

Audit details

Source review establishes this relationship only. Exact evaluated configurations and original numerical review status remain unchanged. These supervised estimators consume ESM-1v predictions and/or embeddings alongside other features. The full estimator uses ESM-1v; it is not identical to ESM-1v.

Field: links:uses_model:discovery-model-esm-1v

Claim: model-evaluation-identity-19d7e0f845794e184f14

Source artifact SHA-256: a3b08cc4a6befd64620cf0f287d78d55a36dc2639955f52c5655f83833c50104

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

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Release 2026-09-29-06401fd5b220 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: proteingym-method-ohe-esm-1v

areas
proteins-complexes
source locator
Table 3, row(ESM-1v)
missing metadata
checkpoint revision: unreported; parameters: unextracted
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