LM-Design | configuration

Overview

Protein model evaluated by the ProteinBench authors under their harness.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

12 evaluations · 12 results. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-PLDDT: De novo backbones based sequence design, length 100 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	78.5 plddt score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-PLDDT: De novo backbones based sequence design, length 100 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 100 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-SCTM: De novo backbones based sequence design, length 100 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.834 sctm score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-SCTM: De novo backbones based sequence design, length 100 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 100 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-PLDDT: De novo backbones based sequence design, length 200 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	58.4 plddt score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-PLDDT: De novo backbones based sequence design, length 200 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 200 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-SCTM: De novo backbones based sequence design, length 200 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.373 sctm score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-SCTM: De novo backbones based sequence design, length 200 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 200 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-PLDDT: De novo backbones based sequence design, length 300 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	69.9 plddt score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-PLDDT: De novo backbones based sequence design, length 300 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 300 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-SCTM: De novo backbones based sequence design, length 300 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.481 sctm score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-SCTM: De novo backbones based sequence design, length 300 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 300 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-PLDDT: De novo backbones based sequence design, length 400 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	59.9 plddt score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-PLDDT: De novo backbones based sequence design, length 400 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 400 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-SCTM: De novo backbones based sequence design, length 400 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.565 sctm score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-SCTM: De novo backbones based sequence design, length 400 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 400 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-PLDDT: De novo backbones based sequence design, length 500 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	56.4 plddt score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-PLDDT: De novo backbones based sequence design, length 500 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 500 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-SCTM: De novo backbones based sequence design, length 500 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.397 sctm score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-SCTM: De novo backbones based sequence design, length 500 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 500 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CAMEO-AAR: Fitting Evolution Distribution, CAMEO AAR Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.57 aar score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CAMEO-AAR: Fitting Evolution Distribution, CAMEO AAR Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(Fitting Evolution Distribution, CAMEO AAR ↑)
Configuration: LM-Design	Task: ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CASP-AAR: Fitting Evolution Distribution, CASP AAR Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.516 aar score · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CASP-AAR: Fitting Evolution Distribution, CASP AAR Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(Fitting Evolution Distribution, CASP AAR ↑)

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Release 2026-09-29-06401fd5b220 · Record review: source checked

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proteinbench primary benchmark evidence · Original source · 2409.06744v1

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Technical metadata and extraction receipts

Stable ID: proteinbench-method-lm-design

areas: proteins-complexes
source locator: Table 2, row(LM-Design)
missing metadata: checkpoint revision: unreported; parameters: unextracted

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