LM-Design | configuration

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

12 evaluations · 12 results. Different protocols are not a single leaderboard.

Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)

Sorted by Plddt (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Protocol and dataset	Plddt	Sctm	Sequence recovery
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-PLDDT: De novo backbones based sequence design, length 100 pLDDT	78.5 (best in column)	Not reported	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-PLDDT: De novo backbones based sequence design, length 300 pLDDT	69.9	Not reported	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-PLDDT: De novo backbones based sequence design, length 400 pLDDT	59.9	Not reported	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-PLDDT: De novo backbones based sequence design, length 200 pLDDT	58.4	Not reported	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-PLDDT: De novo backbones based sequence design, length 500 pLDDT	56.4	Not reported	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-SCTM: De novo backbones based sequence design, length 100 scTM	Not reported	0.834 (best in column)	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-SCTM: De novo backbones based sequence design, length 200 scTM	Not reported	0.373	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-SCTM: De novo backbones based sequence design, length 300 scTM	Not reported	0.481	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-SCTM: De novo backbones based sequence design, length 400 scTM	Not reported	0.565	Not reported
LM-DesignEvaluation	ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-SCTM: De novo backbones based sequence design, length 500 scTM	Not reported	0.397	Not reported
LM-DesignEvaluation	ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CAMEO-AAR: Fitting Evolution Distribution, CAMEO AAR	Not reported	Not reported	0.57 (best in column)
LM-DesignEvaluation	ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CASP-AAR: Fitting Evolution Distribution, CASP AAR	Not reported	Not reported	0.516

All 12 result rows with coverage, uncertainty and sources

Filter evaluations

Tested model or methodProtocolDatasetEvaluation setupMetricEvidence origin

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-PLDDT: De novo backbones based sequence design, length 100 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	78.5 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-PLDDT: De novo backbones based sequence design, length 100 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 100 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-SCTM: De novo backbones based sequence design, length 100 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.834 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-SCTM: De novo backbones based sequence design, length 100 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 100 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-PLDDT: De novo backbones based sequence design, length 200 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	58.4 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-PLDDT: De novo backbones based sequence design, length 200 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 200 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-SCTM: De novo backbones based sequence design, length 200 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.373 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-SCTM: De novo backbones based sequence design, length 200 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 200 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-PLDDT: De novo backbones based sequence design, length 300 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	69.9 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-PLDDT: De novo backbones based sequence design, length 300 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 300 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-SCTM: De novo backbones based sequence design, length 300 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.481 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-SCTM: De novo backbones based sequence design, length 300 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 300 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-PLDDT: De novo backbones based sequence design, length 400 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	59.9 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-PLDDT: De novo backbones based sequence design, length 400 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 400 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-SCTM: De novo backbones based sequence design, length 400 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.565 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-SCTM: De novo backbones based sequence design, length 400 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 400 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-PLDDT: De novo backbones based sequence design, length 500 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	56.4 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-PLDDT: De novo backbones based sequence design, length 500 pLDDT Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 500 pLDDT ↑)
Configuration: LM-Design	Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-SCTM: De novo backbones based sequence design, length 500 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.397 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-SCTM: De novo backbones based sequence design, length 500 scTM Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 500 scTM ↑)
Configuration: LM-Design	Task: ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CAMEO-AAR: Fitting Evolution Distribution, CAMEO AAR Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.57 Sequence recovery fraction · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CAMEO-AAR: Fitting Evolution Distribution, CAMEO AAR Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(Fitting Evolution Distribution, CAMEO AAR ↑)
Configuration: LM-Design	Task: ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CASP-AAR: Fitting Evolution Distribution, CASP AAR Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split)	0.516 Sequence recovery fraction · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source LM-Design on ProteinBench IF-FITTING-EVOLUTION-DISTRIBUTION-CASP-AAR: Fitting Evolution Distribution, CASP AAR Inverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(Fitting Evolution Distribution, CASP AAR ↑)

Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.

Use this configuration

How it works, versions and access

Additional methodological details, versions and access terms have not yet been extracted into a structured profile for this configuration. Consult the linked sources and evaluation records below.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

0 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statement	Original source and location	Review and provenance

No evidence rows match these filters. Choose another scope or clear the search.

How to read the evidence

Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

1 source record and release history

proteinbench primary benchmark evidence · Original source · 2409.06744v1

Download this release (gzip)

Technical metadata and extraction receipts

Stable ID: proteinbench-method-lm-design

areas: proteins-complexes
source locator: Table 2, row(LM-Design)
missing metadata: checkpoint revision: reason: unreported; parameters: reason: unextracted
provenance note: Protein model evaluated by the ProteinBench authors under their harness.

Related records