The split of CASP, CAMEO and de novo backbones that ProteinBench evaluated on. The upstream dataset release is not catalogued here, so no claim is made that this matches its original splits.
44 evaluations · 44 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-PLDDT: De novo backbones based sequence design, length 100 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 88.8 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 100 pLDDT ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-SCTM: De novo backbones based sequence design, length 100 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.81 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 100 scTM ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-PLDDT: De novo backbones based sequence design, length 200 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 69.7 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 200 pLDDT ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-SCTM: De novo backbones based sequence design, length 200 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.635 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 200 scTM ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-PLDDT: De novo backbones based sequence design, length 300 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 74.4 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 300 pLDDT ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-SCTM: De novo backbones based sequence design, length 300 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.336 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 300 scTM ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-PLDDT: De novo backbones based sequence design, length 400 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 64.6 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 400 pLDDT ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-SCTM: De novo backbones based sequence design, length 400 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.449 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 400 scTM ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-PLDDT: De novo backbones based sequence design, length 500 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 59 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 500 pLDDT ↑) |
| Configuration: ESM-IF1 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-SCTM: De novo backbones based sequence design, length 500 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.462 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM-IF1), column(De novo backbones based sequence design, length 500 scTM ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-PLDDT: De novo backbones based sequence design, length 100 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 86.6 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 100 pLDDT ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-SCTM: De novo backbones based sequence design, length 100 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.942 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 100 scTM ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-PLDDT: De novo backbones based sequence design, length 200 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 60.7 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 200 pLDDT ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-SCTM: De novo backbones based sequence design, length 200 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.486 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 200 scTM ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-PLDDT: De novo backbones based sequence design, length 300 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 70.8 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 300 pLDDT ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-SCTM: De novo backbones based sequence design, length 300 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.632 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 300 scTM ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-PLDDT: De novo backbones based sequence design, length 400 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 62.6 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 400 pLDDT ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-400-SCTM: De novo backbones based sequence design, length 400 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.564 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 400 scTM ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-PLDDT: De novo backbones based sequence design, length 500 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 59.4 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 500 pLDDT ↑) |
| Configuration: ESM3 | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-500-SCTM: De novo backbones based sequence design, length 500 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.452 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(ESM3), column(De novo backbones based sequence design, length 500 scTM ↑) |
| Configuration: LM-Design | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-PLDDT: De novo backbones based sequence design, length 100 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 78.5 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 100 pLDDT ↑) |
| Configuration: LM-Design | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-100-SCTM: De novo backbones based sequence design, length 100 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.834 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 100 scTM ↑) |
| Configuration: LM-Design | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-PLDDT: De novo backbones based sequence design, length 200 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 58.4 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 200 pLDDT ↑) |
| Configuration: LM-Design | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-200-SCTM: De novo backbones based sequence design, length 200 scTM Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 0.373 Sctm unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 200 scTM ↑) |
| Configuration: LM-Design | Task: ProteinBench IF-DE-NOVO-BACKBONES-BASED-SEQUENCE-DESIGN-LENGTH-300-PLDDT: De novo backbones based sequence design, length 300 pLDDT Dataset subset: CASP, CAMEO and de novo backbones (ProteinBench split) | 69.9 Plddt unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceInverse folding: recover a sequence for a given backbone. Values are the median over repeated runs. Aggregation: Not reported proteinbench primary benchmark evidence · Table 2, row(LM-Design), column(De novo backbones based sequence design, length 300 pLDDT ↑) |
Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.
0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.
Release 2026-11-02-a7f03c9e55a5 · Evidence verified: Not verified
Exact outcomes, predictions, identifiers and evaluator are connected.
Missing or unresolved evidence
Verified: Not verified
Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.
Missing or unresolved evidence
Verified: Not verified
A pinned recipe describes the inputs, environment and resource requirements.
Missing or unresolved evidence
Verified: Not verified
Separate data and exposure records support an independent test.
Missing or unresolved evidence
Verified: Not verified
Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.
No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.
This record describes a particular subset or cohort used in an evaluation. Its results do not describe the full dataset.
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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
2 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Description The split of CASP, CAMEO and de novo backbones that ProteinBench evaluated on. The upstream dataset release is not catalogued here, so no claim is made that this matches its original splits. Context-only references | proteinbench primary benchmark evidence No field-specific location recorded Version: 2409.06744v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| Name CASP, CAMEO and de novo backbones (ProteinBench split) Context-only references | proteinbench primary benchmark evidence No field-specific location recorded Version: 2409.06744v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
Stable ID: proteinbench-dataset-casp-cameo-and-de-novo-backbones