False positive rate (percentage of individual reads falsely assigned; mean over seven negative-control libraries) of Kraken2 v2.17.1, headline setting (Tisza et al. 2026) on Seven pathogen-free negative-control read libraries (Tisza et al. 2026)
0.000186% False positive rate (percentage of individual reads falsely assigned; mean over seven negative-control libraries)
Methods
- Tested configuration
- Kraken2 v2.17.1, headline setting (Tisza et al. 2026)
- Protocol
- False positives in seven pathogen-free libraries (Tisza et al. 2026 Table S6)
- Dataset
- Seven pathogen-free negative-control read libraries (Tisza et al. 2026)
- Procedure
- False positives in seven pathogen-free libraries (Tisza et al. 2026 Table S6)
- Evaluation
- Kraken2 v2.17.1 on False positives in seven pathogen-free libraries (Tisza et al. 2026 Table S6)
- Coverage
- Not reported scored / Not reported eligible
- Uncertainty
- Not reported by the source
- Evidence
- Author-reported evaluation · source checkedTisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S6, row 6 (base_tool 'Kraken2'), column 'mean_fp_pct' (cell D6)
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.
Reproduction
- Split
- No split
- Adaptation
- Headline setting: confidence 0.5, minimum-hit-group 2
- Scoring implementation
- Every virus assignment in a pathogen-free library is a false positive. False-positive individual-read percentage uses each library's total reads as the denominator; Sylph read percentages are unavailable.
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 0.0001863292442317588 Individual claims | Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) Supplemental Table S6, row 6 (base_tool 'Kraken2'), column 'mean_fp_pct' (cell D6) Version: bioRxiv 10.64898/2026.09.29.755457 v1 supplementary file DC1 (755457_file02.xlsx) | source checked ["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-11 author reported Audit detailsRe-downloaded the pinned artifact and matched its SHA-256; compared every value with a separate stdlib parser written for this review (the extractor's script was not run) and checked a stratified sample by hand against the rendered table. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record Extraction artifact SHA-256: |
Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
2 source records and release history
- Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Original source · bioRxiv 10.64898/2026.09.29.755457 v1 supplementary file DC1 (755457_file02.xlsx)
- EsViritu is a sensitive and specific profiler for viral pathogen detection and genome recovery in metagenomes · Original source · bioRxiv 10.64898/2026.09.29.755457 v1, posted 2026-09-30; JATS XML
Technical metadata and extraction receipts
Stable ID: rna-pathogen-20261011-tisza2026-result-neg-kraken2-mean-fp-pct
- metric
- false-positive-rate
- metric direction
- lower
- unit
- percent
- printed value
- 0.0001863292442317588
- numeric value
- 0.0001863292442317588
- metric qualifier
- percentage of individual reads falsely assigned; mean over seven negative-control libraries
- source locator
- Supplemental Table S6, row 6 (base_tool 'Kraken2'), column 'mean_fp_pct' (cell D6)
- unit detail
- percent of the library's total individual reads
- missing metadata
- uncertainty: reason: unreported
- review
- method: source-hash-verification; deterministic-table-parse; independent-cell-check; reviewer: claude; reviewer note: Separate Claude review agent (reviewer-path), independent of the extractor; no human review claimed; date: 2026-10-11; artifact sha256: 0559022a3ff5ef5b2682e3c451eda51835c4c8d9be9dfdb1ebc9cd9295fb7701; retrieval url: https://www.biorxiv.org/content/biorxiv/early/2026/09/30/2026.09.29.755457/DC1/embed/media-1.xlsx?download=true; method note: Extracted by deterministic parse of the pinned XLSX sheet XML (extract/extract_tisza2026.py), with header and row labels asserted. printed_value is the cell text, or the shortest decimal that round-trips to the stored number; displayed spreadsheet formatting was not applied.; note: Re-downloaded the pinned artifact and matched its SHA-256; compared every value with a separate stdlib parser written for this review (the extractor's script was not run) and checked a stratified sample by hand against the rendered table.