0 false-negative-count
devries2021-hit-dnastar false-negative-count (PCR-positive hits not reported)
- Tested configuration
- DNAstar as run by an ENNGS laboratory (de Vries et al. 2021)
- Protocol
- Virus hits against RT-PCR: true and false positives, PPV and hit-level sensitivity (de Vries et al. 2021 Supplementary Table 4)
- Dataset
- ENNGS benchmark: 13 clinical metagenomic datasets with RT-PCR results (de Vries et al. 2021)
- Procedure
- rna-pathogen-20261009-protocol-devries2021-hit-level
- Evaluation
- DNAstar: virus hits against RT-PCR (ENNGS)
- Coverage
- Not reported scored / Not reported eligible
- Uncertainty
- Not reported by the source
- Evidence
- Independent external evaluation · source checkedde Vries et al. medRxiv preprint v1, Supplementary Tables 2-4 · Supplementary Table 4, cell Q20, row 'DNAstar', column 'FN (number of PCR-positive hits not reported by mNGS)'
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.
Reproduction
- Split
- No split
- Adaptation
- Each laboratory's own database and reporting criteria
- Scoring implementation
- Organisers' scoring of reported hits against RT-PCR
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 0 Individual claims | de Vries et al. medRxiv preprint v1, Supplementary Tables 2-4 Supplementary Table 4, cell Q20, row 'DNAstar', column 'FN (number of PCR-positive hits not reported by mNGS)' Version: medRxiv 2021.05.04.21256618 version 1, supplementary file media-1.xlsx (sheets SuppS2, SuppS3, SuppS4) | source checked ["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-09 independent paper Audit detailsExtracted by deterministic parse of the pinned XLSX cell XML (extract/extract_rna_pathogen.py), with row and column labels asserted. printed_value is the cell text, or the shortest decimal that round-trips to the stored number; displayed spreadsheet formatting was not applied. Pending independent review. Independent review 2026-10-09: value and identity match the source. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record Extraction artifact SHA-256: |
Sources and history
Release 2026-10-09-8cc1db47c7f9 · Record review: source checked
2 source records and release history
- de Vries et al. medRxiv preprint v1, Supplementary Tables 2-4 · Original source · medRxiv 2021.05.04.21256618 version 1, supplementary file media-1.xlsx (sheets SuppS2, SuppS3, SuppS4)
- Benchmark of thirteen bioinformatic pipelines for metagenomic virus diagnostics using datasets from clinical samples · Original source · medRxiv 2021.05.04.21256618 version 1 (2021-05-08), JATS XML; published as J Clin Virol 141:104908 (doi:10.1016/j.jcv.2021.104908)
Technical metadata and extraction receipts
Stable ID: rna-pathogen-20261009-result-devries2021-hit-dnastar-fn
- metric
- false-negative-count
- metric direction
- lower
- unit
- count
- printed value
- 0
- numeric value
- 0
- source locator
- Supplementary Table 4, cell Q20, row 'DNAstar', column 'FN (number of PCR-positive hits not reported by mNGS)'
- missing metadata
- uncertainty: reason: unreported
- metric qualifier
- PCR-positive hits not reported
- unit detail
- virus hits
- review
- method: source-hash-verification; deterministic-table-parse; independent-cell-check; reviewer: claude; reviewer note: Separate Claude review agent, independent of the extractor; no human review claimed; date: 2026-10-09; artifact sha256: be0ea61fcffe8ea580077467ca19ef1ac39e88bbc82d916bc65b58a6683214f6; retrieval url: https://www.medrxiv.org/content/medrxiv/early/2021/05/08/2021.05.04.21256618/DC1/embed/media-1.xlsx; method note: Re-downloaded the workbook and matched its SHA-256. Read de Vries et al. Supplementary Tables 2 and 4 (medRxiv v1 workbook) with a separate stdlib OOXML reader written for this review (the extractor's script was not run). Checked printed and numeric value, locator, metric, unit and direction from the headers, and the evaluation's configuration, protocol and dataset. Recomputed PPV, sensitivity, TP + FN and TP + FP for every row.; note: Extracted by deterministic parse of the pinned XLSX cell XML (extract/extract_rna_pathogen.py), with row and column labels asserted. printed_value is the cell text, or the shortest decimal that round-trips to the stored number; displayed spreadsheet formatting was not applied. Pending independent review. Independent review 2026-10-09: value and identity match the source.
Related records
- evaluation: DNAstar: virus hits against RT-PCR (ENNGS)