rewirebio.iobenchmarks
Result

0:14:48 runtime

franzoso2025 Sentieon SRR11012406 runtime

Tested configuration
Sentieon DNASeq v202308 on a GCP VM with 64 vCPUs and 57 GB memory (Franzoso et al. 2025)
Protocol
WES FASTQ-to-VCF runtime and cost on GCP, Sentieon versus Parabricks (Franzoso et al. 2025 Table S2)
Dataset
Five WES samples (Twist Core Exome, Illumina NextSeq 500, 2x75 bp) from an HLH-like syndrome study
Procedure
model-execution-20261009-protocol-franzoso2025-wes-gcp
Evaluation
Sentieon on GCP, WES samples (Franzoso et al. 2025)
Coverage
Not reported scored / Not reported eligible
Uncertainty
Not reported by the source: Single run per cell
Evidence
Independent external evaluation · source checkedRapid NGS Analysis on Google Cloud Platform: Performance Benchmark and User Tutorial; Franzoso et al. 2025, Table S2 (runtime and costs per sample) and Table S1 (sample identifiers) · Table S2 (CTS-18-e70416-s002.xlsx), C9; ID 'SRR11012406'; Software 'Sentieon'; column 'Runtime (h/m/s)'

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split
Five samples
Adaptation
Not reported
Scoring implementation
GCP monitoring start and end times; GCP cost

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

2 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-09-8cc1db47c7f9
Property and statementOriginal source and locationReview and provenance
Reported result
0:14:48
Individual claims
Rapid NGS Analysis on Google Cloud Platform: Performance Benchmark and User Tutorial

Original source ↗

Table S2 (CTS-18-e70416-s002.xlsx), C9; ID 'SRR11012406'; Software 'Sentieon'; column 'Runtime (h/m/s)'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Clinical and Translational Science 18(11):e70416, published 2025-11-18; PMC12627752 full-text XML
Retrieved: 2026-10-09T20:22:39Z

source checked

["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-09T20:46:48Z

independent paper

Audit details

Extracted by deterministic parse of the pinned XLSX cell XML (extract/extract_model_execution.py with extract/rawxlsx.py), with the title, headers, sample identifiers (checked against Table S1) and software labels asserted. Runtime cells use built-in number format 21 (h:mm:ss); printed_value is that rendering of the stored day fraction and numeric_value is the same duration in seconds. Cost printed_value is the shortest round-trip decimal of the stored double. Independent review 2026-10-09: printed value, numeric value, metric, qualifier, unit, direction, locator and configuration and protocol identity match the source.

Field: attributes.printed_value

Source artifact SHA-256: 65ddebf128fb41ddf2c2d7d29094871bdeded0ae0c8c4c89acb29884c65f4d38

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Extraction artifact SHA-256: 0b32a6146536f820e547ed5ac458ae789477358dbfdf339a634a9b78e6c60bd7

Extraction artifact

Reported result
0:14:48
Individual claims
Franzoso et al. 2025, Table S2 (runtime and costs per sample) and Table S1 (sample identifiers)

Original source ↗

Table S2 (CTS-18-e70416-s002.xlsx), C9; ID 'SRR11012406'; Software 'Sentieon'; column 'Runtime (h/m/s)'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: CTS-18-e70416-s002.xlsx (Table S2) inside the Europe PMC supplementary files bundle for PMC12627752
Retrieved: 2026-10-09T20:26:38Z

source checked

["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-09T20:46:48Z

independent paper

Audit details

Extracted by deterministic parse of the pinned XLSX cell XML (extract/extract_model_execution.py with extract/rawxlsx.py), with the title, headers, sample identifiers (checked against Table S1) and software labels asserted. Runtime cells use built-in number format 21 (h:mm:ss); printed_value is that rendering of the stored day fraction and numeric_value is the same duration in seconds. Cost printed_value is the shortest round-trip decimal of the stored double. Independent review 2026-10-09: printed value, numeric value, metric, qualifier, unit, direction, locator and configuration and protocol identity match the source.

Field: attributes.printed_value

Source artifact SHA-256: 0b32a6146536f820e547ed5ac458ae789477358dbfdf339a634a9b78e6c60bd7

Hash scope: SHA-256 of CTS-18-e70416-s002.xlsx. Table S1 (CTS-18-e70416-s001.xlsx) from the same bundle has SHA-256 b221919e435217c607ff426d80fc5718c7f4d3e0fbaa6261cf13e8c5b7ae0f4e and is used only to assert sample identifiers. The bundle is assembled per request, so only member hashes are pinned.

Archive member: CTS-18-e70416-s002.xlsx

Inspected artifact

Extraction artifact SHA-256: 0b32a6146536f820e547ed5ac458ae789477358dbfdf339a634a9b78e6c60bd7

Extraction artifact

Sources and history

Release 2026-10-09-8cc1db47c7f9 · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: model-execution-20261009-result-franzoso2025-sentieon-dnaseq-202308-gcp-64vcpu-srr11012406-runtime

metric
runtime
metric direction
lower
unit
second
metric qualifier
FASTQ to VCF; sample SRR11012406
printed value
0:14:48
numeric value
888
raw xml value
1.0277777777777778E-2
workbook number format
built-in 21 (h:mm:ss)
printed value basis
Rendering of the stored day fraction in the cell's h:mm:ss number format; numeric_value is seconds
source locator
Table S2 (CTS-18-e70416-s002.xlsx), C9; ID 'SRR11012406'; Software 'Sentieon'; column 'Runtime (h/m/s)'
missing metadata
uncertainty: reason: unreported; note: Single run per cell
review
method: source-hash-verification; deterministic-table-parse; independent-cell-check; method note: Re-downloaded the Europe PMC supplementaryFiles zip and matched the SHA-256 of CTS-18-e70416-s002.xlsx (and s001.xlsx for sample identifiers). Read the cell XML with a separate stdlib parser written for this review (the extractor's scripts were not imported or run) and checked the number format (built-in 21, h:mm:ss) in xl/styles.xml. Checked raw cell value, printed value (h:mm:ss rendering of the day fraction, or shortest round-trip decimal of the cost), numeric value, metric, qualifier, unit, direction, locator, and the linked evaluation's configuration and protocol.; reviewer: claude; reviewer note: Separate Claude review agent, independent of the extractor; no human review claimed; reviewed at: 2026-10-09T20:46:48Z; artifact sha256: 0b32a6146536f820e547ed5ac458ae789477358dbfdf339a634a9b78e6c60bd7; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12627752/supplementaryFiles; note: Extracted by deterministic parse of the pinned XLSX cell XML (extract/extract_model_execution.py with extract/rawxlsx.py), with the title, headers, sample identifiers (checked against Table S1) and software labels asserted. Runtime cells use built-in number format 21 (h:mm:ss); printed_value is that rendering of the stored day fraction and numeric_value is the same duration in seconds. Cost printed_value is the shortest round-trip decimal of the stored double. Independent review 2026-10-09: printed value, numeric value, metric, qualifier, unit, direction, locator and configuration and protocol identity match the source.
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