rewirebio.iobenchmarks
Protocol

GENEB leaderboard, 10-shot, MCC aggregates

GENEB probing of frozen embeddings, 10-shot regime.

41 evaluations · 615 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

41 recorded evaluations, 615 metric rows. A comparison chart has not yet been validated for these results. The table retains the individual findings and their sources.

View coverage and remaining gaps across all benchmarks

Results

Results are available, but no reviewed comparison panel is linked in this release.

All evaluations

41 evaluations · 615 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.383 MCC (10-shot; category 'Chromatin Acc.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Chromatin Acc.'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.565 MCC (10-shot; category 'Coding/NC')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Coding/NC'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.0346 MCC (10-shot; category 'DNA Methyl.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.DNA Methyl.'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.257 MCC (10-shot; category 'Enhancers')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Enhancers'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.256 MCC (10-shot; category 'Histone Mod.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Histone Mod.'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.0821 MCC (10-shot; category 'lncRNA')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.lncRNA'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.237 MCC (10-shot; macro average: unweighted mean of the 13 category MCCs)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'macro_MCC'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.258 MCC (10-shot; micro average: mean over all 100 tasks)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'micro_MCC'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.122 MCC (10-shot; category 'Mouse Enh.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Mouse Enh.'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.487 MCC (10-shot; category 'Promoters')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Promoters'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.168 MCC (10-shot; category 'Regulatory')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Regulatory'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.419 MCC (10-shot; category 'Species Clf.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Species Clf.'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.0944 MCC (10-shot; category 'Splice Sites')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Splice Sites'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.124 MCC (10-shot; category 'TF Binding')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.TF Binding'
Configuration: agro-NT-1b (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.0893 MCC (10-shot; category 'Virus/Phage')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

agro-NT-1b on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'agro-nucleotide-transformer-1b', key 'cat_MCC.Virus/Phage'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.131 MCC (10-shot; category 'Chromatin Acc.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'cat_MCC.Chromatin Acc.'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.457 MCC (10-shot; category 'Coding/NC')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'cat_MCC.Coding/NC'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.0361 MCC (10-shot; category 'DNA Methyl.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'cat_MCC.DNA Methyl.'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.0615 MCC (10-shot; category 'Enhancers')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'cat_MCC.Enhancers'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.0975 MCC (10-shot; category 'Histone Mod.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'cat_MCC.Histone Mod.'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
-0.00321 MCC (10-shot; category 'lncRNA')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'cat_MCC.lncRNA'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.121 MCC (10-shot; macro average: unweighted mean of the 13 category MCCs)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'macro_MCC'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.109 MCC (10-shot; micro average: mean over all 100 tasks)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'micro_MCC'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.0698 MCC (10-shot; category 'Mouse Enh.')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'cat_MCC.Mouse Enh.'
Configuration: BioFM-265M (GENEB leaderboard)Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks
0.188 MCC (10-shot; category 'Promoters')
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

BioFM-265M on GENEB (10-shot)

lit-genomics-20261011-geneb-protocol-10shot

Aggregation: Not reported

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'BioFM-265M', key 'cat_MCC.Promoters'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Methods and evaluation design

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Recorded evaluations

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Baseline coverage

Reference methods help show what a model adds beyond simple controls. We track a null control and a conventional method for each protocol.

0 of 2 active baseline roles have published Rewire measurements in this release. Measurements on a selected protocol do not establish coverage of an entire suite.

No execution recipe linked to this protocol. Recipe availability does not establish a completed evaluation.

External evaluations
40
unreported
1

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Null control

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Protocol coverage CSV (gzip) · Model evaluation matrix (gzip) · Source table (gzip) · Release and checksums (gzip)

Coverage is derived from release 2026-10-22-1b7cf027e4f6. Source citations describe the original records; they do not validate an unreviewed baseline proposal. No results have been generated by this audit.

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Evidence

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Evidence table

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Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
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Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

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Technical metadata and extraction receipts

Stable ID: lit-genomics-20261011-geneb-protocol-10shot

areas
dna-genomes
contexts
research
protocol
Logistic-regression probe (max_iter=1000) on frozen embeddings, trained per task in the 10-shot regime; MCC aggregated as the micro average over all 100 tasks, the macro average (unweighted mean of the 13 category MCCs) and per category.
version
Leaderboard at commit 9642d481e40c
metric
matthews-correlation-coefficient
metric direction
higher
unit
unitless
limitations
Leaderboard aggregates; per-task values not extracted.
source locator
leaderboard.json data.10shot
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