Evaluation

METAGENE-1 on GENEB (10-shot)

Published comparison transcribed from the pinned source; not reproduced.

Evaluation results

1 evaluation · 15 results. Different protocols are not a single leaderboard.

Protocol: GENEB leaderboard, 10-shot, MCC aggregates · Dataset: GENEB 100 tasks

Sorted by MCC (10-shot; category 'Chromatin Acc.') (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	MCC (10-shot; category 'Chromatin Acc.')	MCC (10-shot; category 'Coding/NC')	MCC (10-shot; category 'DNA Methyl.')	MCC (10-shot; category 'Enhancers')	MCC (10-shot; category 'Histone Mod.')	MCC (10-shot; category 'lncRNA')	MCC (10-shot; category 'Mouse Enh.')	MCC (10-shot; category 'Promoters')	MCC (10-shot; category 'Regulatory')	MCC (10-shot; category 'Species Clf.')	MCC (10-shot; category 'Splice Sites')	MCC (10-shot; category 'TF Binding')	MCC (10-shot; category 'Virus/Phage')	MCC (10-shot; macro average: unweighted mean of the 13 category MCCs)	MCC (10-shot; micro average: mean over all 100 tasks)
METAGENE-1 (GENEB leaderboard)Evaluation	0.355	0.684	0.051	0.299	0.272	0.027	0.159	0.497	0.109	0.473	0.163	0.309	0.158	0.274	0.285

All 15 result rows with coverage, uncertainty and sources

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Tested model or methodProtocolDatasetEvaluation setupMetricEvidence origin

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.355 MCC (10-shot; category 'Chromatin Acc.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Chromatin Acc.'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.684 MCC (10-shot; category 'Coding/NC') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Coding/NC'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.051 MCC (10-shot; category 'DNA Methyl.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.DNA Methyl.'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.299 MCC (10-shot; category 'Enhancers') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Enhancers'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.272 MCC (10-shot; category 'Histone Mod.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Histone Mod.'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.027 MCC (10-shot; category 'lncRNA') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.lncRNA'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.274 MCC (10-shot; macro average: unweighted mean of the 13 category MCCs) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'macro_MCC'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.285 MCC (10-shot; micro average: mean over all 100 tasks) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'micro_MCC'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.159 MCC (10-shot; category 'Mouse Enh.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Mouse Enh.'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.497 MCC (10-shot; category 'Promoters') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Promoters'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.109 MCC (10-shot; category 'Regulatory') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Regulatory'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.473 MCC (10-shot; category 'Species Clf.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Species Clf.'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.163 MCC (10-shot; category 'Splice Sites') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Splice Sites'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.309 MCC (10-shot; category 'TF Binding') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.TF Binding'
Configuration: METAGENE-1 (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.158 MCC (10-shot; category 'Virus/Phage') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source METAGENE-1 on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'METAGENE-1', key 'cat_MCC.Virus/Phage'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

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Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

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Evaluation procedure

GENEB leaderboard, 10-shot, MCC aggregates

Configuration: METAGENE-1 (GENEB leaderboard)
Protocol: GENEB leaderboard, 10-shot, MCC aggregates
Dataset: GENEB 100 tasks

origin: Independent external evaluation
configuration: Primary source as retrieved 2026-10-11
protocol id: lit-genomics-20261011-geneb-protocol-10shot
dataset version: Not reported
split: 10-shot
population: 100 tasks
inputs: DNA sequence; frozen embeddings
adaptation: Logistic-regression probe on frozen embeddings
metric implementation: MCC
aggregation: micro, macro and per-category averages
budget: 10-shot

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split: 10-shot
Adaptation: Logistic-regression probe on frozen embeddings
Scoring implementation: MCC

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Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

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Evidence table

Inspect claims, sources and review details

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19 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
Comparison: adaptation Logistic-regression probe on frozen embeddings Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.adaptation` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: aggregation micro, macro and per-category averages Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.aggregation` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: budget 10-shot Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.budget` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: dataset version Not reported Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	missing or unspecified No individual claim review recorded independent paper Audit details Field: `attributes.comparison.dataset_version` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: inputs DNA sequence; frozen embeddings Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.inputs` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: metric implementation MCC Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.metric_implementation` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: population 100 tasks Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.population` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: protocol id lit-genomics-20261011-geneb-protocol-10shot Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.protocol_id` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: split 10-shot Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.split` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Limitations 1 values Leaderboard entry status: 'official' (official=True). Context-only references	GENEB leaderboard (leaderboard.json, 13 task-type aggregates) Original source ↗ leaderboard.json data.10shot, model 'METAGENE-1' Version: Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22) Retrieved: 2026-10-11T01:42:40Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.limitations` Source artifact SHA-256: `7c8a9d985e7c2df24514f309bf6102e4f81d9da1b9afbb74856d87e78e01f738` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact

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Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release history

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · Original source · Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22)

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Technical metadata and extraction receipts

Stable ID: lit-genomics-20261011-geneb-eval-metagene-1-10shot

areas: dna-genomes
contexts: research
origin: independent_paper
protocol: lit-genomics-20261011-geneb-protocol-10shot
version: Primary source as retrieved 2026-10-11
comparison: protocol id: lit-genomics-20261011-geneb-protocol-10shot; dataset version: Not reported; split: 10-shot; population: 100 tasks; inputs: DNA sequence; frozen embeddings; adaptation: Logistic-regression probe on frozen embeddings; metric implementation: MCC; aggregation: micro, macro and per-category averages; budget: 10-shot
source locator: leaderboard.json data.10shot, model 'METAGENE-1'
missing metadata: comparison.dataset version: reason: unreported
limitations: Leaderboard entry status: 'official' (official=True).

Related records

system: METAGENE-1 (GENEB leaderboard)
assessment: GENEB leaderboard, 10-shot, MCC aggregates
data: GENEB 100 tasks
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Chromatin Acc.
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Coding/NC
evaluation: METAGENE-1 GENEB 10shot cat_MCC.DNA Methyl.
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Enhancers
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Histone Mod.
evaluation: METAGENE-1 GENEB 10shot cat_MCC.lncRNA
evaluation: METAGENE-1 GENEB 10shot macro_MCC
evaluation: METAGENE-1 GENEB 10shot micro_MCC
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Mouse Enh.
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Promoters
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Regulatory
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Species Clf.
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Splice Sites
evaluation: METAGENE-1 GENEB 10shot cat_MCC.TF Binding
evaluation: METAGENE-1 GENEB 10shot cat_MCC.Virus/Phage

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