Tranception
Autoregressive transformer protein language model that can retrieve homologous sequences at inference to predict the fitness of substitutions, multiple mutants and indels; ProteinGym scores it with and without retrieval as a zero-shot substitution baseline.
16 evaluations · 118 results1 configuration with further results
Overview
An explanatory profile has not yet been reviewed for this record.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
16 evaluations · 118 results. Different protocols are not a single leaderboard.
Filter evaluations
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym AMFR official zero-shot Spearman snapshot Dataset subset: ProteinGym AMFR 4G3O official snapshot cohort | 0.356 Spearman unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L AMFR official snapshot Not reported Aggregation: Not reported ProteinGym AMFR assay-level Spearman comparison · DMS_substitutions_Spearman_DMS_level.csv line 15, DMS ID=AMFR_HUMAN_Tsuboyama_2023_4G3O, column=Tranception L |
| Configuration: Tranception L no retrieval [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym AMFR official zero-shot Spearman snapshot Dataset subset: ProteinGym AMFR 4G3O official snapshot cohort | -0.275 Spearman unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L no retrieval AMFR official snapshot Not reported Aggregation: Not reported ProteinGym AMFR assay-level Spearman comparison · DMS_substitutions_Spearman_DMS_level.csv line 15, DMS ID=AMFR_HUMAN_Tsuboyama_2023_4G3O, column=Tranception L no retrieval |
| Configuration: Tranception M [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym AMFR official zero-shot Spearman snapshot Dataset subset: ProteinGym AMFR 4G3O official snapshot cohort | 0.402 Spearman unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception M AMFR official snapshot Not reported Aggregation: Not reported ProteinGym AMFR assay-level Spearman comparison · DMS_substitutions_Spearman_DMS_level.csv line 15, DMS ID=AMFR_HUMAN_Tsuboyama_2023_4G3O, column=Tranception M |
| Configuration: Tranception M no retrieval [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym AMFR official zero-shot Spearman snapshot Dataset subset: ProteinGym AMFR 4G3O official snapshot cohort | -0.139 Spearman unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception M no retrieval AMFR official snapshot Not reported Aggregation: Not reported ProteinGym AMFR assay-level Spearman comparison · DMS_substitutions_Spearman_DMS_level.csv line 15, DMS ID=AMFR_HUMAN_Tsuboyama_2023_4G3O, column=Tranception M no retrieval |
| Configuration: Tranception S [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym AMFR official zero-shot Spearman snapshot Dataset subset: ProteinGym AMFR 4G3O official snapshot cohort | 0.392 Spearman unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception S AMFR official snapshot Not reported Aggregation: Not reported ProteinGym AMFR assay-level Spearman comparison · DMS_substitutions_Spearman_DMS_level.csv line 15, DMS ID=AMFR_HUMAN_Tsuboyama_2023_4G3O, column=Tranception S |
| Configuration: Tranception S no retrieval [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym AMFR official zero-shot Spearman snapshot Dataset subset: ProteinGym AMFR 4G3O official snapshot cohort | -0.287 Spearman unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception S no retrieval AMFR official snapshot Not reported Aggregation: Not reported ProteinGym AMFR assay-level Spearman comparison · DMS_substitutions_Spearman_DMS_level.csv line 15, DMS ID=AMFR_HUMAN_Tsuboyama_2023_4G3O, column=Tranception S no retrieval |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) Dataset subset: ProteinGym clinical indel benchmark at commit 144fe22 | 0.843 AUROC (ProteinGym clinical indels, zero-shot, Average_AUC over proteins) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) Aggregation: Not reported ProteinGym clinical zero-shot indels AUC summary at commit 144fe22 · benchmarks/clinical_zero_shot/indels/AUC/Summary_performance_clinical_indels_AUC.csv line 11, row 'Tranception L', column 'Average_AUC' |
| Configuration: Tranception L no retrieval [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) Dataset subset: ProteinGym clinical indel benchmark at commit 144fe22 | 0.852 AUROC (ProteinGym clinical indels, zero-shot, Average_AUC over proteins) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L no retrieval: ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) Aggregation: Not reported ProteinGym clinical zero-shot indels AUC summary at commit 144fe22 · benchmarks/clinical_zero_shot/indels/AUC/Summary_performance_clinical_indels_AUC.csv line 7, row 'Tranception L no retrieval', column 'Average_AUC' |
| Configuration: Tranception M [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) Dataset subset: ProteinGym clinical indel benchmark at commit 144fe22 | 0.828 AUROC (ProteinGym clinical indels, zero-shot, Average_AUC over proteins) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception M: ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) Aggregation: Not reported ProteinGym clinical zero-shot indels AUC summary at commit 144fe22 · benchmarks/clinical_zero_shot/indels/AUC/Summary_performance_clinical_indels_AUC.csv line 14, row 'Tranception M', column 'Average_AUC' |
| Configuration: Tranception M no retrieval [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) Dataset subset: ProteinGym clinical indel benchmark at commit 144fe22 | 0.831 AUROC (ProteinGym clinical indels, zero-shot, Average_AUC over proteins) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception M no retrieval: ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) ProteinGym clinical indels, zero-shot, average AUC (commit 144fe22) Aggregation: Not reported ProteinGym clinical zero-shot indels AUC summary at commit 144fe22 · benchmarks/clinical_zero_shot/indels/AUC/Summary_performance_clinical_indels_AUC.csv line 13, row 'Tranception M no retrieval', column 'Average_AUC' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.434 Spearman (ProteinGym zero-shot DMS substitutions, mean over selection types of the per-type mean over proteins of assay-level Spearman (all 217 assays)) unitless · higher Uncertainty: SE 0.007. From compute_bootstrap_standard_error_functional_categories in performance_DMS_benchmarks.py at 144fe22 (default 10,000 resamples, lines 95-111 and 310-315); not an absolute standard error of the model's own average. Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Average_Spearman' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.422 Spearman (ProteinGym zero-shot DMS substitutions, variants with 1 substitution: mean over protein and selection-type groups of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Depth_1' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.254 Spearman (ProteinGym zero-shot DMS substitutions, variants with 2 substitutions: mean over protein and selection-type groups of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Depth_2' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.346 Spearman (ProteinGym zero-shot DMS substitutions, variants with 3 substitutions: mean over protein and selection-type groups of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Depth_3' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.325 Spearman (ProteinGym zero-shot DMS substitutions, variants with 4 substitutions: mean over protein and selection-type groups of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Depth_4' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.387 Spearman (ProteinGym zero-shot DMS substitutions, variants with 5 or more substitutions: mean over protein and selection-type groups of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Depth_5+' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.465 Spearman (ProteinGym zero-shot DMS substitutions, Activity assays: mean over proteins of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Function_Activity' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.349 Spearman (ProteinGym zero-shot DMS substitutions, Binding assays: mean over proteins of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Function_Binding' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.45 Spearman (ProteinGym zero-shot DMS substitutions, Expression assays: mean over proteins of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Function_Expression' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.435 Spearman (ProteinGym zero-shot DMS substitutions, Organismal fitness assays: mean over proteins of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Function_OrganismalFitness' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.471 Spearman (ProteinGym zero-shot DMS substitutions, Stability assays: mean over proteins of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Function_Stability' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.471 Spearman (ProteinGym zero-shot DMS substitutions, High MSA depth proteins: mean over proteins of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'High_MSA_depth' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.421 Spearman (ProteinGym zero-shot DMS substitutions, Low MSA depth proteins: mean over proteins of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Low_MSA_depth' |
| Configuration: Tranception L [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.443 Spearman (ProteinGym zero-shot DMS substitutions, Medium MSA depth proteins: mean over proteins of assay-level Spearman) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 34, row 'Tranception L', column 'Medium_MSA_depth' |
| Configuration: Tranception L no retrieval [ProteinGym 144fe22b snapshot] | Protocol: ProteinGym v1.3 zero-shot DMS substitutions Dataset subset: ProteinGym DMS substitution assays at commit 144fe22 (217 assays) | 0.374 Spearman (ProteinGym zero-shot DMS substitutions, mean over selection types of the per-type mean over proteins of assay-level Spearman (all 217 assays)) unitless · higher Uncertainty: SE 0.009. From compute_bootstrap_standard_error_functional_categories in performance_DMS_benchmarks.py at 144fe22 (default 10,000 resamples, lines 95-111 and 310-315); not an absolute standard error of the model's own average. Coverage: Not reported scored / Not reported eligible | Evaluation origin not reported · Source checkedMethods, coverage and sourceTranception L no retrieval: ProteinGym zero-shot DMS substitutions summary (144fe22) ProteinGym zero-shot DMS substitutions, Spearman summary Aggregation: Not reported ProteinGym zero-shot DMS substitutions Spearman summary at commit 144fe22 · benchmarks/DMS_zero_shot/substitutions/Spearman/Summary_performance_DMS_substitutions_Spearman.csv line 69, row 'Tranception L no retrieval', column 'Average_Spearman' |
Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.
Further results on linked records
One linked record has results that are not included above, because no reviewed claim yet ties the link to this model. Each record keeps its own settings and evaluations, and its scores are on its own page.
- Tranception (Livesey and Marsh 2025) Configuration · configuration · 6 evaluations · 7 results
Use this model
How it works, versions and access
Versions and evaluated configurations
- Tranception L [ProteinGym 144fe22b snapshot] · configuration of
- Tranception L no retrieval [ProteinGym 144fe22b snapshot] · configuration of
- Tranception M [ProteinGym 144fe22b snapshot] · configuration of
- Tranception M no retrieval [ProteinGym 144fe22b snapshot] · configuration of
- Tranception S [ProteinGym 144fe22b snapshot] · configuration of
- Tranception S no retrieval [ProteinGym 144fe22b snapshot] · configuration of
Strengths, limitations and unresolved questions
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
3 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Description Autoregressive transformer protein language model that can retrieve homologous sequences at inference to predict the fitness of substitutions, multiple mutants and indels; ProteinGym scores it with and without retrieval as a zero-shot substitution baseline. Individual claims | Abstract: Tranception: protein fitness prediction with autoregressive transformers and inference-time retrieval uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-tranception: abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: arXiv API entry for 2205.13760v1 (title and abstract) | source checked ["automated-source-review","ai-assisted-source-review"] · 2026-10-10 Audit detailsDescription written from the cited source text; provenance text was generic and is kept here as previous_value. Independent review 2026-10-10: corrected. ProteinGym scores Tranception with and without retrieval, and the record's locator is the 'Tranception S no retrieval' column; the description now covers both. Field: Claim: metadata-correction-64e879f8e75018b07409 Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Description Autoregressive transformer protein language model that can retrieve homologous sequences at inference to predict the fitness of substitutions, multiple mutants and indels; ProteinGym scores it with and without retrieval as a zero-shot substitution baseline. Individual claims | OATML-Markslab/ProteinGym / README.md uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-tranception: abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Git commit 144fe22b07dfaeec2b366f2346203a9838a55b4c | source checked ["automated-source-review","ai-assisted-source-review"] · 2026-10-10 Audit detailsDescription written from the cited source text; provenance text was generic and is kept here as previous_value. Independent review 2026-10-10: corrected. ProteinGym scores Tranception with and without retrieval, and the record's locator is the 'Tranception S no retrieval' column; the description now covers both. Field: Claim: metadata-correction-64e879f8e75018b07409 Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Description Autoregressive transformer protein language model that can retrieve homologous sequences at inference to predict the fitness of substitutions, multiple mutants and indels; ProteinGym scores it with and without retrieval as a zero-shot substitution baseline. Individual claims | ProteinGym AMFR assay-level Spearman comparison uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-tranception: abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 144fe22b07dfaeec2b366f2346203a9838a55b4c | source checked ["automated-source-review","ai-assisted-source-review"] · 2026-10-10 Audit detailsDescription written from the cited source text; provenance text was generic and is kept here as previous_value. Independent review 2026-10-10: corrected. ProteinGym scores Tranception with and without retrieval, and the record's locator is the 'Tranception S no retrieval' column; the description now covers both. Field: Claim: metadata-correction-64e879f8e75018b07409 Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
3 source records and release history
- ProteinGym AMFR assay-level Spearman comparison · Original source · 144fe22b07dfaeec2b366f2346203a9838a55b4c
- OATML-Markslab/ProteinGym / README.md · Original source · Git commit 144fe22b07dfaeec2b366f2346203a9838a55b4c
- Abstract: Tranception: protein fitness prediction with autoregressive transformers and inference-time retrieval · Original source · arXiv API entry for 2205.13760v1 (title and abstract)
Technical metadata and extraction receipts
Stable ID: uc20260930-model-tranception
- areas
- proteins-complexes
- source locator
- Pinned ProteinGym Spearman CSV header: Tranception S no retrieval
- review
- method: automated-source-review; reviewer: codex; reviewed at: 2026-09-30T21:40:59.576893+00:00; scope: Primary-source transcription and catalogue applicability audit; not human scientific review or independent experimental reproduction.; reviewer note: role: experimental use-case curation
- entity level
- family
- identity scope
- Family/method identity only; no undocumented checkpoint equivalence.
Related records
- subject: Tranception: description
- configuration of: Tranception L [ProteinGym 144fe22b snapshot]
- configuration of: Tranception L no retrieval [ProteinGym 144fe22b snapshot]
- configuration of: Tranception M [ProteinGym 144fe22b snapshot]
- configuration of: Tranception M no retrieval [ProteinGym 144fe22b snapshot]
- configuration of: Tranception S [ProteinGym 144fe22b snapshot]
- configuration of: Tranception S no retrieval [ProteinGym 144fe22b snapshot]
- configuration of: Tranception (Livesey and Marsh 2025)