| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.934 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell S22, row 'Kaiju', column 'AUC' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 34.8 regression-intercept unitless · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell Y22, row 'Kaiju', column 'LR intercept' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 22.6% pearson-r-squared percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell Z22, row 'Kaiju', column 'LR r2, %' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | -1.64 regression-slope unitless · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell X22, row 'Kaiju', column 'LR slope' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.996 negative-predictive-value fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell W22, row 'Kaiju', column 'NPV (ROC)' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.778 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell V22, row 'Kaiju', column 'PPV (ROC)' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.125 roc-distance unitless · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell R22, row 'Kaiju', column 'Informedness' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.875 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell T22, row 'Kaiju', column 'SN (ROC)' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.992 specificity fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell U22, row 'Kaiju', column 'SL (ROC)' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 17 count count · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell AA22, row 'Kaiju', column 'Taxa' |
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| Configuration: Kaiju, human reads removed (Bowtie2 to GRCh38) before classification (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 17 count count · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceKaiju, human reads removed (Bowtie2 to GRCh38) before classification: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads', cell AB22, row 'Kaiju', column 'Taxa with reads >10' |
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