Published RNA metagenomic pathogen-detection comparison; transcribed, not reproduced.
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Release 2026-10-09-ba02f2f4a36e · Evidence verified: Not verified
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1 evaluation · 11 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.968 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell D12, row 'Centrifuge', column 'AUC' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 35.5 regression-intercept unitless · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell J12, row 'Centrifuge', column 'LR intercept' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 35.5% pearson-r-squared percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell K12, row 'Centrifuge', column 'LR r2, %' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | -2.03 regression-slope unitless · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell I12, row 'Centrifuge', column 'LR slope' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.997 negative-predictive-value fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell H12, row 'Centrifuge', column 'NPV (ROC)' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.415 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell G12, row 'Centrifuge', column 'PPV (ROC)' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.0926 roc-distance unitless · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell C12, row 'Centrifuge', column 'Informedness' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.917 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell E12, row 'Centrifuge', column 'SN (ROC)' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.96 specificity fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell F12, row 'Centrifuge', column 'SL (ROC)' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 17 count count · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell L12, row 'Centrifuge', column 'Taxa' |
| Configuration: Centrifuge, all trimmed reads (human reads included) (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 0 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 17 count count · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261009-protocol-carbo2022-species-cutoff-0 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', cell M12, row 'Centrifuge', column 'Taxa with reads >0' |
Source checking is not independent reproduction. Release 2026-10-09-ba02f2f4a36e.
rna-pathogen-20261009-protocol-carbo2022-species-cutoff-0
Metadata review: source checked. Unreported conditions prevent automatic comparisons.
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
36 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.comparison.adaptation Viral RefSeq database built 2020-12-27 (Genome Detective: own database) Context-only references | Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Pathogens 11(3):340, published 2022-03-11; PMC8953373 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.adaptation Viral RefSeq database built 2020-12-27 (Genome Detective: own database) Context-only references | Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: medRxiv 2022.01.21.22269647 version 1 (2022-01-21), supplementary file media-1.xlsx | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.aggregation All PCR targets pooled Context-only references | Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Pathogens 11(3):340, published 2022-03-11; PMC8953373 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.aggregation All PCR targets pooled Context-only references | Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: medRxiv 2022.01.21.22269647 version 1 (2022-01-21), supplementary file media-1.xlsx | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.budget Not reported Context-only references | Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Pathogens 11(3):340, published 2022-03-11; PMC8953373 full-text XML | missing or unspecified No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.budget Not reported Context-only references | Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: medRxiv 2022.01.21.22269647 version 1 (2022-01-21), supplementary file media-1.xlsx | missing or unspecified No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.dataset_version SRX6713943-SRX6714030 Context-only references | Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Pathogens 11(3):340, published 2022-03-11; PMC8953373 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.dataset_version SRX6713943-SRX6714030 Context-only references | Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: medRxiv 2022.01.21.22269647 version 1 (2022-01-21), supplementary file media-1.xlsx | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.inputs Trimmed NextSeq 150 bp paired-end reads Context-only references | Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Pathogens 11(3):340, published 2022-03-11; PMC8953373 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.inputs Trimmed NextSeq 150 bp paired-end reads Context-only references | Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 Supplementary Table 1 sheet 'Suppl table 1-Species', block 'incl. human reads', row 12; Row rank '#' as printed: 5 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: medRxiv 2022.01.21.22269647 version 1 (2022-01-21), supplementary file media-1.xlsx | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-09-ba02f2f4a36e · Record review: source checked
Stable ID: rna-pathogen-20261009-eval-carbo2022-species-cutoff-0-centrifuge-incl-human