rewirebio.iobenchmarks
Evaluation

LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026)

Published fusion caller comparison; transcribed, not reproduced.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-10-09-ba02f2f4a36e · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • recipe pinned: verification is missing
  • resource estimate: verification is missing

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 4 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)Protocol: Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3)
Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)
0.81 f1-score
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026)

rna-fusion-20261009-protocol-lin2026-high-depth

Aggregation: Not reported

Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 3, row 'LongGF', column 'F1'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)Protocol: Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3)
Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)
0.95 precision
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026)

rna-fusion-20261009-protocol-lin2026-high-depth

Aggregation: Not reported

Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 3, row 'LongGF', column 'Precision'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)Protocol: Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3)
Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)
0.7 recall
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026)

rna-fusion-20261009-protocol-lin2026-high-depth

Aggregation: Not reported

Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 3, row 'LongGF', column 'Sensitivity (recall)'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)Protocol: Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3)
Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)
0.96 specificity
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026)

rna-fusion-20261009-protocol-lin2026-high-depth

Aggregation: Not reported

Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 3, row 'LongGF', column 'Specificity'

Source checking is not independent reproduction. Release 2026-10-09-ba02f2f4a36e.

Evaluation procedure

rna-fusion-20261009-protocol-lin2026-high-depth

Configuration
LongGF on nanopore cDNA reads (Lin et al. 2026)
Protocol
Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3)
Dataset
Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)
origin
Independent external evaluation
configuration
Primary source as retrieved 2026-10-09
protocol id
rna-fusion-20261009-protocol-lin2026-high-depth
dataset version
Not reported
split
high-depth
population
51 samples, 27 with a known B-ALL fusion
inputs
Nanopore PCR-cDNA reads
adaptation
Not reported
metric implementation
Dominant-fusion per-sample classification (Methods)
aggregation
Per sample or sequencing run
budget
Not reported

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
high-depth
Adaptation
Not reported
Scoring implementation
Dominant-fusion per-sample classification (Methods)

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

18 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-09-ba02f2f4a36e
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
Not reported
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.aggregation
Per sample or sequencing run
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.inputs
Nanopore PCR-cDNA reads
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.metric_implementation
Dominant-fusion per-sample classification (Methods)
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.population
51 samples, 27 with a known B-ALL fusion
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.population

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.protocol_id
rna-fusion-20261009-protocol-lin2026-high-depth
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.split
high-depth
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.split

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.origin
independent_paper
Context-only references
Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia

Original source ↗

Table 3, row 'LongGF'

Version: Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML
Retrieved: 2026-10-09T20:38:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.origin

Source artifact SHA-256: 8cc3b4bca5e2fe9b068a1e891366854d974f3df3102425959e600b9ea19f87b6

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-10-09-ba02f2f4a36e · Record review: source checked

1 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: rna-fusion-20261009-eval-lin2026-longgf-high-depth

areas
rna-transcriptomes
contexts
clinical_research
origin
independent_paper
protocol
rna-fusion-20261009-protocol-lin2026-high-depth
version
Primary source as retrieved 2026-10-09
comparison
protocol id: rna-fusion-20261009-protocol-lin2026-high-depth; dataset version: Not reported; split: high-depth; population: 51 samples, 27 with a known B-ALL fusion; inputs: Nanopore PCR-cDNA reads; adaptation: Not reported; metric implementation: Dominant-fusion per-sample classification (Methods); aggregation: Per sample or sequencing run; budget: Not reported
source locator
Table 3, row 'LongGF'
missing metadata
comparison.dataset version: reason: unreported
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