Configuration

LongGF on nanopore cDNA reads (Lin et al. 2026)

LongGF as run in the cited comparison.

Overview

LongGF as run in the cited comparison.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

2 evaluations · 8 results. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)	Protocol: Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3) Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)	0.81 f1-score fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026) rna-fusion-20261009-protocol-lin2026-high-depth Aggregation: Not reported Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 3, row 'LongGF', column 'F1'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)	Protocol: Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3) Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)	0.95 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026) rna-fusion-20261009-protocol-lin2026-high-depth Aggregation: Not reported Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 3, row 'LongGF', column 'Precision'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)	Protocol: Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3) Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)	0.7 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026) rna-fusion-20261009-protocol-lin2026-high-depth Aggregation: Not reported Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 3, row 'LongGF', column 'Sensitivity (recall)'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)	Protocol: Paediatric B-ALL nanopore WTS, high-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 3) Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)	0.96 specificity fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026) rna-fusion-20261009-protocol-lin2026-high-depth Aggregation: Not reported Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 3, row 'LongGF', column 'Specificity'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)	Protocol: Paediatric B-ALL nanopore WTS, low-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 6) Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)	0.27 f1-score fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source LongGF on paediatric B-ALL nanopore WTS, low-depth (Lin et al. 2026) rna-fusion-20261009-protocol-lin2026-low-depth Aggregation: Not reported Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 6, row 'LongGF', column 'F1'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)	Protocol: Paediatric B-ALL nanopore WTS, low-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 6) Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)	0.93 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source LongGF on paediatric B-ALL nanopore WTS, low-depth (Lin et al. 2026) rna-fusion-20261009-protocol-lin2026-low-depth Aggregation: Not reported Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 6, row 'LongGF', column 'Precision'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)	Protocol: Paediatric B-ALL nanopore WTS, low-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 6) Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)	0.16 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source LongGF on paediatric B-ALL nanopore WTS, low-depth (Lin et al. 2026) rna-fusion-20261009-protocol-lin2026-low-depth Aggregation: Not reported Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 6, row 'LongGF', column 'Sensitivity (recall)'
Configuration: LongGF on nanopore cDNA reads (Lin et al. 2026)	Protocol: Paediatric B-ALL nanopore WTS, low-depth cohort, dominant-fusion classification (Lin et al. 2026 Table 6) Dataset: Paediatric B-ALL nanopore PCR-cDNA whole-transcriptome sequencing (UNC, St Jude, ECOG-ACRIN)	0.97 specificity fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source LongGF on paediatric B-ALL nanopore WTS, low-depth (Lin et al. 2026) rna-fusion-20261009-protocol-lin2026-low-depth Aggregation: Not reported Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Table 6, row 'LongGF', column 'Specificity'

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Release 2026-10-09-ba02f2f4a36e · Record review: source checked

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Long-Read Whole-Transcriptome Sequencing and Selective Gene Panel Profiling Enable Sensitive Detection of Fusion Oncogenes in Pediatric B-Cell Acute Lymphoblastic Leukemia · Original source · Journal of Molecular Diagnostics 28(5):406, published 2026-02-10; PMC13197905 full-text XML

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Technical metadata and extraction receipts

Stable ID: rna-fusion-20261009-config-lin2026-longgf

areas: rna-transcriptomes
contexts: clinical_research
method types: conventional_pipeline
reported name: LongGF
foundation model eligible: false
protocol: GitHub install (WGLab/LongGF) adapted for RefSeq GTF, minimap2 BAM sorted by read name; parameters in Supplemental Table S3
source locator: Materials and Methods 'LongGF' and 'Data Preprocessing'
missing metadata: version: reason: unreported; note: No release number printed; installation source and access dates only

Related records

configuration of: LongGF
system: LongGF on paediatric B-ALL nanopore WTS, high-depth (Lin et al. 2026)
system: LongGF on paediatric B-ALL nanopore WTS, low-depth (Lin et al. 2026)

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