One seed-0 random ranking on all 2,972 AMFR variants. This is one complete assay, not the full ProteinGym track or an estimate of a chance-performance interval.
1 evaluation · 5 results. Different protocols are not a single leaderboard.
Protocol: ProteinGym v1.3 AMFR seeded-random control · Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants
Sorted by AUROC (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | AUROC | MCC | NDCG at 10% | Spearman | Top 10% recall |
|---|---|---|---|---|---|
| Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay)Evaluation | 0.514 | 0.019 | 0.526 | 0.008 | 0.087 |
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.514 AUROC unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.AUC |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.019 MCC unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.MCC |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.526 NDCG at 10% unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.NDCG |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.008 Spearman unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.Spearman |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.087 Top 10% recall unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.Top_recall |
Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.
0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.
Release 2026-11-02-a7f03c9e55a5 · Evidence verified: Not verified
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Missing or unresolved evidence
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Missing or unresolved evidence
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A pinned recipe describes the inputs, environment and resource requirements.
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Separate data and exposure records support an independent test.
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No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.
ProteinGym v1.3 AMFR substitution assay
Metadata review: source checked. Unreported conditions prevent automatic comparisons.
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Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
198 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation none; seed fixed before scoring Context-only references | Seeded random ranking control: audit metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: adaptation none; seed fixed before scoring Context-only references | Seeded random ranking control: execution and verification instructions metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: adaptation none; seed fixed before scoring Context-only references | Seeded random ranking control: report metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation single assay Context-only references | Seeded random ranking control: audit metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation single assay Context-only references | Seeded random ranking control: execution and verification instructions metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation single assay Context-only references | Seeded random ranking control: report metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget one local CPU evaluation; no held-out hyperparameter selection Context-only references | Seeded random ranking control: audit metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget one local CPU evaluation; no held-out hyperparameter selection Context-only references | Seeded random ranking control: execution and verification instructions metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget one local CPU evaluation; no held-out hyperparameter selection Context-only references | Seeded random ranking control: report metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: dataset version rewire-dataset-proteingym-amfr-random-v13 Context-only references | Seeded random ranking control: audit metrics; coverage; protocol_results Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded rewire run Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
Stable ID: rewire-local-20260921-evaluation-proteingym-random