The same AMFR assay inputs used in the earlier ESM-2 evaluation, described independently of its scoring method. This additional catalogue identity does not represent another dataset or independent source.
1 evaluation · 5 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.514 AUROC unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.AUC |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.019 MCC unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.MCC |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.526 NDCG at 10% unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.NDCG |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.008 Spearman unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.Spearman |
| Configuration: Seeded random ranking control (ProteinGym v1.3 AMFR substitution assay) | Protocol: ProteinGym v1.3 AMFR seeded-random control Dataset subset: ProteinGym v1.3 AMFR stability assay, 2,972 variants | 0.087 Top 10% recall unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 2972/2972 scored | Rewire evaluation · Source checkedMethods, coverage and sourceSeeded random ranking control on ProteinGym v1.3 AMFR substitution assay ProteinGym v1.3 AMFR substitution assay Aggregation: Not reported Seeded random ranking control: report; Seeded random ranking control: audit · protocol_results.per_assay.AMFR_HUMAN_Tsuboyama_2023_4G3O.metrics.Top_recall |
Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.
0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.
Release 2026-11-02-a7f03c9e55a5 · Evidence verified: Not verified
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A pinned recipe describes the inputs, environment and resource requirements.
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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
30 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Provenance: assay sha256: AMFR HUMAN Tsuboyama 2023 4G3O dd911d925eca79329a496eb6cb7b181ab448e15db244daf1c1f9c01e8a704c2a Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Provenance: assay sha256: AMFR HUMAN Tsuboyama 2023 4G3O dd911d925eca79329a496eb6cb7b181ab448e15db244daf1c1f9c01e8a704c2a Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Provenance: data verification local_bytes_hashed_not_independently_source_verified Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Provenance: data verification local_bytes_hashed_not_independently_source_verified Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Provenance: expected hashes checked1 values
| Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Provenance: expected hashes checked1 values
| Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Provenance: reference sha256 a8f498011532a74aa9fe556a50555a75e928c5837d19c06a87592ae04049b308 Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Provenance: reference sha256 a8f498011532a74aa9fe556a50555a75e928c5837d19c06a87592ae04049b308 Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Provenance: source url https://github.com/OATML-Markslab/ProteinGym/tree/144fe22b07dfaeec2b366f2346203a9838a55b4c Context-only references | Seeded random ranking control: audit coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Provenance: source url https://github.com/OATML-Markslab/ProteinGym/tree/144fe22b07dfaeec2b366f2346203a9838a55b4c Context-only references | Seeded random ranking control: report coverage; protocol_configuration.assays; verification.json source_alignment and source_assay_sha256 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 1663d1f04b2bbd6dfcff77fea78129d30b0de191 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
Stable ID: rewire-dataset-proteingym-amfr-random-v13