rewire.itbenchmarks
Evaluation

Original: Protective-antigen classification feature comparison

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-09-29-06401fd5b220 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

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  • artifact hashes: verification is missing
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  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

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  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
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Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
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  • independent validation: verification is missing
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Verified: Not verified

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Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 7 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)
Dataset: Protective-antigen classification feature comparison
0.94 AUROC
fraction · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Original: Protective-antigen classification feature comparison

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Aggregation: Not reported

Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column AUROC; XML row2 column8
Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)
Dataset: Protective-antigen classification feature comparison
0.96 ± 0.008 Weighted F1
fraction · higher

Uncertainty: type: reported_plus_minus_type_unresolved; value: 0.008

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Original: Protective-antigen classification feature comparison

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Aggregation: Not reported

Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Weighted F1; XML row2 column5
Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)
Dataset: Protective-antigen classification feature comparison
0.78 ± 0.046 MCC
dimensionless · higher

Uncertainty: type: reported_plus_minus_type_unresolved; value: 0.046

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Original: Protective-antigen classification feature comparison

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Aggregation: Not reported

Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column MCC; XML row2 column6
Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)
Dataset: Protective-antigen classification feature comparison
0.84 ± 0.049 AUPRC
fraction · higher

Uncertainty: type: reported_plus_minus_type_unresolved; value: 0.049

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Original: Protective-antigen classification feature comparison

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Aggregation: Not reported

Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column AUPRC; XML row2 column7
Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)
Dataset: Protective-antigen classification feature comparison
0.74 ± 0.071 Sensitivity
fraction · higher

Uncertainty: type: reported_plus_minus_type_unresolved; value: 0.071

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Original: Protective-antigen classification feature comparison

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Aggregation: Not reported

Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Sensitivity; XML row2 column3
Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)
Dataset: Protective-antigen classification feature comparison
0.96 ± 0.008 Val Accuracy
fraction · higher

Uncertainty: type: reported_plus_minus_type_unresolved; value: 0.008

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Original: Protective-antigen classification feature comparison

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Aggregation: Not reported

Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Val Accuracy; XML row2 column2
Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)
Dataset: Protective-antigen classification feature comparison
0.99 ± 0.004 Specificity
fraction · higher

Uncertainty: type: reported_plus_minus_type_unresolved; value: 0.004

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Original: Protective-antigen classification feature comparison

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Aggregation: Not reported

Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Specificity; XML row2 column4

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

Evaluation procedure

Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.

Configuration
Original
Protocol
Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)
Dataset
Protective-antigen classification feature comparison
origin
Author-reported evaluation
configuration
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
protocol id
paper-protocol-a7bf3c8f6b432c3093
dataset version
Not reported
split
372 protection-positive and 3,720 protection-negative samples.
subset
Protective-antigen classification feature comparison
population
Not reported
aggregation
Not reported
inputs
Not reported
adaptation
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
budget
Not reported
metric implementation
Not reported

Metadata review: needs review. Unreported conditions prevent automatic comparisons.

Reproduction

Split
372 protection-positive and 3,720 protection-negative samples.
Adaptation
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
Scoring implementation
Not reported

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

19 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.aggregation
Not reported
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.inputs
Not reported
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.metric_implementation
Not reported
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.population
Not reported
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.population

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.protocol_id
paper-protocol-a7bf3c8f6b432c3093
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.split
372 protection-positive and 3,720 protection-negative samples.
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.split

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.subset
Protective-antigen classification feature comparison
Context-only references
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features

Original source ↗

Table 1.: Val Accuracy, Protective-antigen classification feature comparison

Version: preprint version in PMC
Retrieved: 2026-09-17T07:56:15.123850+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.subset

Source artifact SHA-256: b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-29-06401fd5b220 · Record review: needs review

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: paper-evaluation-b77f564626c00343d2

areas
proteins-complexes
tasks
vaccine-antigen candidate prediction
origin
author_reported
protocol
Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.
version
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
comparison
protocol id: paper-protocol-a7bf3c8f6b432c3093; dataset version: Not reported; split: 372 protection-positive and 3,720 protection-negative samples.; subset: Protective-antigen classification feature comparison; population: Not reported; aggregation: Not reported; inputs: Not reported; adaptation: Paper-specific evaluated pipeline; exact checkpoint not inferred from label; budget: Not reported; metric implementation: Not reported
source locator
Table 1.: Val Accuracy, Protective-antigen classification feature comparison
missing metadata
checkpoint revision: unextracted; budget: unreported; split manifest: unextracted
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