Published result; transcribed, not reproduced.
1 evaluation · 6 results. Different protocols are not a single leaderboard.
Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) · Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each
Sorted by Runtime (Average total time per compound on one NVIDIA H100 80 GB, averaged over the five targets) (lower is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | Runtime (Average total time per compound on one NVIDIA H100 80 GB, averaged over the five targets) | Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target a2a) | Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ar) | Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target cdk2) | Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ctsk) | Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target hdac2) |
|---|---|---|---|---|---|---|
| Protenix, 1 sample, timed per compoundEvaluation | 12.4 | 20.1 | 9.46 | 10.5 | 8.49 | 13.4 |
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Protenix, 1 sample, timed per compound | Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each | 20.1 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target a2a) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceContinued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'a2a' |
| Configuration: Protenix, 1 sample, timed per compound | Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each | 9.46 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ar) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceContinued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'ar' |
| Configuration: Protenix, 1 sample, timed per compound | Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each | 12.4 Runtime (Average total time per compound on one NVIDIA H100 80 GB, averaged over the five targets) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceContinued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'Average' |
| Configuration: Protenix, 1 sample, timed per compound | Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each | 10.5 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target cdk2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceContinued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'cdk2' |
| Configuration: Protenix, 1 sample, timed per compound | Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each | 8.49 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ctsk) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceContinued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'ctsk' |
| Configuration: Protenix, 1 sample, timed per compound | Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each | 13.4 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target hdac2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceContinued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'hdac2' |
Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.
0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.
Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified
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Missing or unresolved evidence
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Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5)
Metadata review: source checked. Unreported conditions prevent automatic comparisons.
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
19 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation None; default or recommended settings Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Per target, and the average over the five targets Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget One NVIDIA H100 with 80 GB of memory Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: dataset version DEKOIS 2.0 as distributed at http://www.dekois.com Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: inputs Pre-computed MSAs and ligand SMILES Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: metric implementation Total time for a target divided by its number of compounds Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: population Five DEKOIS 2.0 targets (a2a, ar, cdk2, ctsk, hdac2), 400 decoys per target Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: protocol id hitdisc-20261022-protocol-shen-speed Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: split Five representative targets with 400 randomly selected decoys each Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Inference hardware A single NVIDIA H100 with 80 GB of memory Context-only references | Shen et al. 2025, Chemical Science (Europe PMC full text) Table 5, row '(row continued, sample count 1)', column 'Number of samples' = 1 Version: PMC12704515 (Chem Sci, published 2025-12-11) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: hitdisc-20261022-eval-speed-speed-protenix-1