Dataset

DEKOIS 2.0 speed subset, five targets with 400 decoys each

Five DEKOIS 2.0 targets, each with 400 randomly selected decoys, used to time the co-folding methods per compound.

Evaluation results

6 evaluations · 36 results. Different protocols are not a single leaderboard.

Filter evaluations

Tested model or methodProtocolDatasetEvaluation setupMetricEvidence origin

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: AF3, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	19.1 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target a2a) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Continued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'a2a'
Configuration: AF3, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	10.6 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ar) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Continued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'ar'
Configuration: AF3, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	13 Runtime (Average total time per compound on one NVIDIA H100 80 GB, averaged over the five targets) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Continued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'Average'
Configuration: AF3, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	12.8 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target cdk2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Continued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'cdk2'
Configuration: AF3, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	6.7 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ctsk) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Continued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'ctsk'
Configuration: AF3, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	15.7 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target hdac2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Continued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'hdac2'
Configuration: AF3, 5 samples, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	26.3 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target a2a) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source AF3 with 5 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'AF3' (Number of samples = 5), column 'a2a'
Configuration: AF3, 5 samples, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	15.4 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ar) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source AF3 with 5 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'AF3' (Number of samples = 5), column 'ar'
Configuration: AF3, 5 samples, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	18.4 Runtime (Average total time per compound on one NVIDIA H100 80 GB, averaged over the five targets) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source AF3 with 5 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'AF3' (Number of samples = 5), column 'Average'
Configuration: AF3, 5 samples, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	17.5 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target cdk2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source AF3 with 5 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'AF3' (Number of samples = 5), column 'cdk2'
Configuration: AF3, 5 samples, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	10.3 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ctsk) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source AF3 with 5 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'AF3' (Number of samples = 5), column 'ctsk'
Configuration: AF3, 5 samples, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	22.6 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target hdac2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source AF3 with 5 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'AF3' (Number of samples = 5), column 'hdac2'
Configuration: Boltz-2, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	21.5 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target a2a) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2' (Number of samples = 1), column 'a2a'
Configuration: Boltz-2, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	15.4 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ar) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2' (Number of samples = 1), column 'ar'
Configuration: Boltz-2, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	17.8 Runtime (Average total time per compound on one NVIDIA H100 80 GB, averaged over the five targets) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2' (Number of samples = 1), column 'Average'
Configuration: Boltz-2, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	16.8 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target cdk2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2' (Number of samples = 1), column 'cdk2'
Configuration: Boltz-2, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	16.2 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ctsk) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2' (Number of samples = 1), column 'ctsk'
Configuration: Boltz-2, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	18.9 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target hdac2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2' (Number of samples = 1), column 'hdac2'
Configuration: Boltz-2 (without affinity module), 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	10.8 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target a2a) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 (without affinity module) with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2 (without affinity module)' (Number of samples = 1), column 'a2a'
Configuration: Boltz-2 (without affinity module), 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	6.14 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ar) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 (without affinity module) with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2 (without affinity module)' (Number of samples = 1), column 'ar'
Configuration: Boltz-2 (without affinity module), 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	7.79 Runtime (Average total time per compound on one NVIDIA H100 80 GB, averaged over the five targets) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 (without affinity module) with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2 (without affinity module)' (Number of samples = 1), column 'Average'
Configuration: Boltz-2 (without affinity module), 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	7.11 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target cdk2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 (without affinity module) with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2 (without affinity module)' (Number of samples = 1), column 'cdk2'
Configuration: Boltz-2 (without affinity module), 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	6.05 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target ctsk) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 (without affinity module) with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2 (without affinity module)' (Number of samples = 1), column 'ctsk'
Configuration: Boltz-2 (without affinity module), 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	8.79 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target hdac2) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Boltz-2 (without affinity module) with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row 'Boltz-2 (without affinity module)' (Number of samples = 1), column 'hdac2'
Configuration: Protenix, 1 sample, timed per compound	Protocol: Co-folding time per compound on five DEKOIS 2.0 targets (Shen et al. 2025 Table 5) Dataset: DEKOIS 2.0 speed subset, five targets with 400 decoys each	20.1 Runtime (Average total time per compound on one NVIDIA H100 80 GB, DEKOIS 2.0 target a2a) second · lower Uncertainty: Not reported by the source: The source prints no interval or spread for this value Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Continued row with 1 sample(s): time per compound (Shen et al. 2025 Table 5) hitdisc-20261022-protocol-shen-speed Aggregation: Not reported Shen et al. 2025, Chemical Science (Europe PMC full text) · Table 5, row '(row continued, sample count 1)' (Number of samples = 1), column 'a2a'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

No verified artifact manifest is linked to this exact record.
File checksums match the recorded files: not yet verified
Predictions are matched to the right samples: not yet verified
Score meaning and direction are confirmed: not yet verified
Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

No verified artifact manifest is linked to this exact record.
File checksums match the recorded files: not yet verified
Predictions are matched to the right samples: not yet verified
Score meaning and direction are confirmed: not yet verified
Metrics are recomputed from the saved predictions: not yet verified
Sample annotations are recorded: not yet verified
Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

No verified artifact manifest is linked to this exact record.
File checksums match the recorded files: not yet verified
Predictions are matched to the right samples: not yet verified
Score meaning and direction are confirmed: not yet verified
A pinned run recipe exists: not yet verified
Compute requirements are estimated: not yet verified

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

No verified artifact manifest is linked to this exact record.
File checksums match the recorded files: not yet verified
Predictions are matched to the right samples: not yet verified
Score meaning and direction are confirmed: not yet verified
Independent validation data exist: not yet verified
Overlap with training data is checked: not yet verified

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Dataset and evaluation context

A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

7 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
Population Five targets; 400 randomly selected decoys per target Context-only references	Shen et al. 2025, Chemical Science (Europe PMC full text) Original source ↗ Results 'Assessment of computational efficiency'; Table 5 caption Version: PMC12704515 (Chem Sci, published 2025-12-11) Retrieved: 2026-10-22T11:52:32Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.population` Source artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Hash scope: Hash scope not separately documented; inspect source record
Source location Results 'Assessment of computational efficiency'; Table 5 caption Context-only references	Shen et al. 2025, Chemical Science (Europe PMC full text) Original source ↗ Results 'Assessment of computational efficiency'; Table 5 caption Version: PMC12704515 (Chem Sci, published 2025-12-11) Retrieved: 2026-10-22T11:52:32Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Hash scope: Hash scope not separately documented; inspect source record
Split Five representative targets (a2a, ar, cdk2, ctsk, hdac2), each with 400 randomly selected decoys Context-only references	Shen et al. 2025, Chemical Science (Europe PMC full text) Original source ↗ Results 'Assessment of computational efficiency'; Table 5 caption Version: PMC12704515 (Chem Sci, published 2025-12-11) Retrieved: 2026-10-22T11:52:32Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.split` Source artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Hash scope: Hash scope not separately documented; inspect source record
Total targets 5 Context-only references	Shen et al. 2025, Chemical Science (Europe PMC full text) Original source ↗ Results 'Assessment of computational efficiency'; Table 5 caption Version: PMC12704515 (Chem Sci, published 2025-12-11) Retrieved: 2026-10-22T11:52:32Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.total_targets` Source artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Hash scope: Hash scope not separately documented; inspect source record
Version DEKOIS 2.0 as distributed at http://www.dekois.com; no release identifier is printed Context-only references	Shen et al. 2025, Chemical Science (Europe PMC full text) Original source ↗ Results 'Assessment of computational efficiency'; Table 5 caption Version: PMC12704515 (Chem Sci, published 2025-12-11) Retrieved: 2026-10-22T11:52:32Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.version` Source artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Hash scope: Hash scope not separately documented; inspect source record
Description Five DEKOIS 2.0 targets, each with 400 randomly selected decoys, used to time the co-folding methods per compound. Context-only references	Shen et al. 2025, Chemical Science (Europe PMC full text) Original source ↗ Results 'Assessment of computational efficiency'; Table 5 caption Version: PMC12704515 (Chem Sci, published 2025-12-11) Retrieved: 2026-10-22T11:52:32Z	not individually reviewed No individual claim review recorded Audit details Field: `description` Source artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Hash scope: Hash scope not separately documented; inspect source record
Name DEKOIS 2.0 speed subset, five targets with 400 decoys each Context-only references	Shen et al. 2025, Chemical Science (Europe PMC full text) Original source ↗ Results 'Assessment of computational efficiency'; Table 5 caption Version: PMC12704515 (Chem Sci, published 2025-12-11) Retrieved: 2026-10-22T11:52:32Z	not individually reviewed No individual claim review recorded Audit details Field: `name` Source artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Hash scope: Hash scope not separately documented; inspect source record

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release history

Shen et al. 2025, Chemical Science (Europe PMC full text) · Original source · PMC12704515 (Chem Sci, published 2025-12-11)

Download this release (gzip)

Technical metadata and extraction receipts

Stable ID: hitdisc-20261022-dataset-dekois2-speed5

areas: molecular-interactions
contexts: research
version: DEKOIS 2.0 as distributed at http://www.dekois.com; no release identifier is printed
split: Five representative targets (a2a, ar, cdk2, ctsk, hdac2), each with 400 randomly selected decoys
population: Five targets; 400 randomly selected decoys per target
total targets: 5
source locator: Results 'Assessment of computational efficiency'; Table 5 caption
missing metadata: split seeds: reason: unreported; note: The source does not state the seed for the random decoy selection
review: method: scope-review; automated-source-review; reviewer: claude; reviewer note: Claude review agent, independent of the extraction agent; no human review claimed; date: 2026-10-22; method note: Read the record against the pinned sources and against docs/use-cases.md and docs/record-contract.md.; note: Record checked against the pinned source and the record contract. Transcription checked; not reproduced and not reviewed by a human scientist.; artifact sha256: 11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12704515/fullTextXML; receipt: data/omics/use-case-coverage-hitdisc-20261022/review.json

Related records

Suggest a correction