rewirebio.iobenchmarks
Evaluation

RNABERT on NT-splice-sites-donors

Published comparison; transcribed, not reproduced.

Evaluation results

1 evaluation · 4 results. Different protocols are not a single leaderboard.

Protocol: NT-splice-sites-donors splice-site classification, fine-tuned models (You et al. 2026 Supplementary Table 4) · Dataset: Nucleotide Transformer benchmark splice-site dataset, donors

Sorted by Accuracy (NT-splice-sites-donors, fine-tuned) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationAccuracy (NT-splice-sites-donors, fine-tuned)F1 (NT-splice-sites-donors, fine-tuned)Precision (NT-splice-sites-donors, fine-tuned)Recall (NT-splice-sites-donors, fine-tuned)
RNABERT fine-tuned with an appended convolutional layer (You et al. 2026)Evaluation0.9673(0.0008)0.9673(0.0008)0.9673(0.0008)0.9673(0.0008)
All 4 result rows with coverage, uncertainty and sources
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Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: RNABERT fine-tuned with an appended convolutional layer (You et al. 2026)Protocol: NT-splice-sites-donors splice-site classification, fine-tuned models (You et al. 2026 Supplementary Table 4)
Dataset: Nucleotide Transformer benchmark splice-site dataset, donors
0.9673(0.0008) Accuracy (NT-splice-sites-donors, fine-tuned)
fraction · higher

Uncertainty: SD 0.0008

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT on NT-splice-sites-donors

gfm2-20261011-you2026-protocol-nt-splice-donors

Aggregation: Not reported

Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT', column 'Accuracy'
Configuration: RNABERT fine-tuned with an appended convolutional layer (You et al. 2026)Protocol: NT-splice-sites-donors splice-site classification, fine-tuned models (You et al. 2026 Supplementary Table 4)
Dataset: Nucleotide Transformer benchmark splice-site dataset, donors
0.9673(0.0008) F1 (NT-splice-sites-donors, fine-tuned)
fraction · higher

Uncertainty: SD 0.0008

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT on NT-splice-sites-donors

gfm2-20261011-you2026-protocol-nt-splice-donors

Aggregation: Not reported

Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT', column 'F1 Score'
Configuration: RNABERT fine-tuned with an appended convolutional layer (You et al. 2026)Protocol: NT-splice-sites-donors splice-site classification, fine-tuned models (You et al. 2026 Supplementary Table 4)
Dataset: Nucleotide Transformer benchmark splice-site dataset, donors
0.9673(0.0008) Precision (NT-splice-sites-donors, fine-tuned)
fraction · higher

Uncertainty: SD 0.0008

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT on NT-splice-sites-donors

gfm2-20261011-you2026-protocol-nt-splice-donors

Aggregation: Not reported

Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT', column 'Precision'
Configuration: RNABERT fine-tuned with an appended convolutional layer (You et al. 2026)Protocol: NT-splice-sites-donors splice-site classification, fine-tuned models (You et al. 2026 Supplementary Table 4)
Dataset: Nucleotide Transformer benchmark splice-site dataset, donors
0.9673(0.0008) Recall (NT-splice-sites-donors, fine-tuned)
fraction · higher

Uncertainty: SD 0.0008

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT on NT-splice-sites-donors

gfm2-20261011-you2026-protocol-nt-splice-donors

Aggregation: Not reported

Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT', column 'Recall'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

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  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

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  • File checksums match the recorded files: not yet verified
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  • Score meaning and direction are confirmed: not yet verified
  • A pinned run recipe exists: not yet verified
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Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
  • Overlap with training data is checked: not yet verified

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Evaluation procedure

NT-splice-sites-donors splice-site classification, fine-tuned models (You et al. 2026 Supplementary Table 4)

Configuration
RNABERT fine-tuned with an appended convolutional layer (You et al. 2026)
Protocol
NT-splice-sites-donors splice-site classification, fine-tuned models (You et al. 2026 Supplementary Table 4)
Dataset
Nucleotide Transformer benchmark splice-site dataset, donors
origin
Independent external evaluation
configuration
Primary source as retrieved 2026-10-11
protocol id
gfm2-20261011-you2026-protocol-nt-splice-donors
dataset version
NT-splice-sites-donors as used by You et al. 2026
split
19,775 train / 2,198 test
population
147 species, 2 categories; 21,973 sequences
inputs
DNA sequence from the NT benchmark splice-site dataset; length not stated in this source
adaptation
Fine-tuned with an appended convolution head
metric implementation
F1 score, precision, recall and accuracy
aggregation
Mean over three fine-tuning runs
budget
Not reported

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
19,775 train / 2,198 test
Adaptation
Fine-tuned with an appended convolution head
Scoring implementation
F1 score, precision, recall and accuracy

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

38 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Comparison: adaptation
Fine-tuned with an appended convolution head
Context-only references
Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nat Commun 17:223, published online 2025-12-07; PMC12780105 full-text XML
Retrieved: 2026-10-11T00:55:34Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 2c6b2816846a21296c56b4dd58f3d1e8810e9d96e224d3ab21b5eb8faa9928e4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: adaptation
Fine-tuned with an appended convolution head
Context-only references
You et al. 2026, Supplementary Information

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41467_2025_66899_MOESM1_ESM.pdf inside the Europe PMC supplementaryFiles zip (outer zip 9a0d0a8d8643872ab265e3e6ed7eea944563da4861bf764f97c68fc6aa502525, assembled per request; the member hash is the bound artifact)
Retrieved: 2026-10-11T00:55:34Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: cbb69e05045a4526e35479d2c1361ebb9cfadfd968e00675390dad597035d882

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: aggregation
Mean over three fine-tuning runs
Context-only references
Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nat Commun 17:223, published online 2025-12-07; PMC12780105 full-text XML
Retrieved: 2026-10-11T00:55:34Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 2c6b2816846a21296c56b4dd58f3d1e8810e9d96e224d3ab21b5eb8faa9928e4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: aggregation
Mean over three fine-tuning runs
Context-only references
You et al. 2026, Supplementary Information

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41467_2025_66899_MOESM1_ESM.pdf inside the Europe PMC supplementaryFiles zip (outer zip 9a0d0a8d8643872ab265e3e6ed7eea944563da4861bf764f97c68fc6aa502525, assembled per request; the member hash is the bound artifact)
Retrieved: 2026-10-11T00:55:34Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: cbb69e05045a4526e35479d2c1361ebb9cfadfd968e00675390dad597035d882

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: budget
Not reported
Context-only references
Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nat Commun 17:223, published online 2025-12-07; PMC12780105 full-text XML
Retrieved: 2026-10-11T00:55:34Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 2c6b2816846a21296c56b4dd58f3d1e8810e9d96e224d3ab21b5eb8faa9928e4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: budget
Not reported
Context-only references
You et al. 2026, Supplementary Information

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41467_2025_66899_MOESM1_ESM.pdf inside the Europe PMC supplementaryFiles zip (outer zip 9a0d0a8d8643872ab265e3e6ed7eea944563da4861bf764f97c68fc6aa502525, assembled per request; the member hash is the bound artifact)
Retrieved: 2026-10-11T00:55:34Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: cbb69e05045a4526e35479d2c1361ebb9cfadfd968e00675390dad597035d882

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: dataset version
NT-splice-sites-donors as used by You et al. 2026
Context-only references
Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nat Commun 17:223, published online 2025-12-07; PMC12780105 full-text XML
Retrieved: 2026-10-11T00:55:34Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: 2c6b2816846a21296c56b4dd58f3d1e8810e9d96e224d3ab21b5eb8faa9928e4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: dataset version
NT-splice-sites-donors as used by You et al. 2026
Context-only references
You et al. 2026, Supplementary Information

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41467_2025_66899_MOESM1_ESM.pdf inside the Europe PMC supplementaryFiles zip (outer zip 9a0d0a8d8643872ab265e3e6ed7eea944563da4861bf764f97c68fc6aa502525, assembled per request; the member hash is the bound artifact)
Retrieved: 2026-10-11T00:55:34Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: cbb69e05045a4526e35479d2c1361ebb9cfadfd968e00675390dad597035d882

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: inputs
DNA sequence from the NT benchmark splice-site dataset; length not stated in this source
Context-only references
Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nat Commun 17:223, published online 2025-12-07; PMC12780105 full-text XML
Retrieved: 2026-10-11T00:55:34Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: 2c6b2816846a21296c56b4dd58f3d1e8810e9d96e224d3ab21b5eb8faa9928e4

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Comparison: inputs
DNA sequence from the NT benchmark splice-site dataset; length not stated in this source
Context-only references
You et al. 2026, Supplementary Information

Original source ↗

Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41467_2025_66899_MOESM1_ESM.pdf inside the Europe PMC supplementaryFiles zip (outer zip 9a0d0a8d8643872ab265e3e6ed7eea944563da4861bf764f97c68fc6aa502525, assembled per request; the member hash is the bound artifact)
Retrieved: 2026-10-11T00:55:34Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: cbb69e05045a4526e35479d2c1361ebb9cfadfd968e00675390dad597035d882

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: gfm2-20261011-you2026-eval-t4-nt-splice-donors-rnabert

areas
dna-genomes
contexts
research
origin
independent_paper
protocol
gfm2-20261011-you2026-protocol-nt-splice-donors
version
Primary source as retrieved 2026-10-11
comparison
protocol id: gfm2-20261011-you2026-protocol-nt-splice-donors; dataset version: NT-splice-sites-donors as used by You et al. 2026; split: 19,775 train / 2,198 test; population: 147 species, 2 categories; 21,973 sequences; inputs: DNA sequence from the NT benchmark splice-site dataset; length not stated in this source; adaptation: Fine-tuned with an appended convolution head; metric implementation: F1 score, precision, recall and accuracy; aggregation: Mean over three fine-tuning runs; budget: Not reported
source locator
Supplementary Table 4, block 'NT-splice-sites-donors', row 'RNABERT'
limitations
Fine-tuned and tested three times with different random initialisations; the printed spread is the standard deviation over those three runs (Methods, 'To ensure the reliability of our findings').; Input length for the NT splice-site datasets is not stated in this source; the 500 bp division applies to the GTEx task.; Each language model is fine-tuned with an appended convolution head, so the comparison measures the adapted model, not zero-shot likelihood.; Values are read from the Supplementary Information tables behind the figures; the main-text figures are not read.
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