Genie 3 short monomer generation evaluation of Proteus on Unconditional short monomer Novelty, AFDB, scored with Novelty, AFDB.
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1 evaluation · 1 result. Different protocols are not a single leaderboard.
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| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Proteus | Protocol: Genie 3 short monomer generation novelty-afdb: Unconditional short monomer Novelty, AFDB Dataset subset: 500 generated monomers per run; lengths 50–250 in steps of 50; three runs (Genie 3 short monomer generation split) | 0.37 novelty_afdb reported score · higher Uncertainty: Not reported Coverage: generated per run: 500; repeats: 3; note: Three repeated runs; metric-specific valid subsets not assigned a pooled denominator. | Author-reported evaluation · Source checkedMethods, coverage and sourceProteus on Genie 3 short monomer generation novelty-afdb: Unconditional short monomer Novelty, AFDB Unconditional short monomer generation: 100 structures at each length 50, 100, 150, 200 and 250 (500 samples per run); 3 repeated runs; Table 3 reports the authors’ average across runs. Designability uses minimum C-alpha scRMSD <2 angstrom across 8 ProteinMPNN sequences refolded with ESMFold. Diversity and novelty use FoldSeek release 10 (2025-01-19); exact definitions and reference sets in Appendix B.1. Method-specific checkpoints and sampling settings remain as Appendix B.2. Aggregation: Mean over three repeated runs Genie 3 primary paper v1, Table 3 · PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB |
Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.
Unconditional short monomer generation: 100 structures at each length 50, 100, 150, 200 and 250 (500 samples per run); 3 repeated runs; Table 3 reports the authors’ average across runs. Designability uses minimum C-alpha scRMSD <2 angstrom across 8 ProteinMPNN sequences refolded with ESMFold. Diversity and novelty use FoldSeek release 10 (2025-01-19); exact definitions and reference sets in Appendix B.1. Method-specific checkpoints and sampling settings remain as Appendix B.2.
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15 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.adaptation Author-evaluated unconditional generation with method-specific released checkpoint and sampling settings; no additional training inferred. Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.metric_implementation Novelty, AFDB Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.protocol_id genie3-2026-table3-task-novelty-afdb Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.evaluation_group_id genie3-2026-table3-method-proteus-genie3-2026-table3-dataset-500-generated-monomers-per-run-lengths-50-250-in-steps-of-50-three-runs-evaluation-setup Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.evidence_overlap Five metrics from the same Table 3 generated sets are one evaluation setup; per-run Tables 4 and 5 repeat the same underlying experiment and are not independent evidence. Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.origin author_reported Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.protocol Unconditional short monomer generation: 100 structures at each length 50, 100, 150, 200 and 250 (500 samples per run); 3 repeated runs; Table 3 reports the authors’ average across runs. Designability uses minimum C-alpha scRMSD <2 angstrom across 8 ProteinMPNN sequences refolded with ESMFold. Diversity and novelty use FoldSeek release 10 (2025-01-19); exact definitions and reference sets in Appendix B.1. Method-specific checkpoints and sampling settings remain as Appendix B.2. Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.published_score_reproduction false Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.source_locator PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.suite_complete false Context-only references | Genie 3 primary paper v1, Table 3 PDF page 20, Appendix B.3, Table 3, data row 3 (Proteus), column Novelty, AFDB Version: 10.64898/2026.05.01.722168v1; posted 2026-05-05 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
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Release 2026-09-29-06401fd5b220 · Record review: source checked
Stable ID: genie3-2026-table3-evaluation-proteus-novelty-afdb