Published CNV caller comparison; transcribed, not reproduced.
These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.
Release 2026-10-09-9307685239b3 · Evidence verified: Not verified
Exact outcomes, predictions, identifiers and evaluator are connected.
Missing or unresolved evidence
Verified: Not verified
Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.
Missing or unresolved evidence
Verified: Not verified
A pinned recipe describes the inputs, environment and resource requirements.
Missing or unresolved evidence
Verified: Not verified
Separate data and exposure records support an independent test.
Missing or unresolved evidence
Verified: Not verified
Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.
No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.
1 evaluation · 6 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: DRAGEN 4.2 high-sensitivity mode with custom artifact filters (HS-F) | Protocol: Coriell virtual gene-panel CNV precision by exon count and length (De La Vega et al. Table 1) Dataset: 25 Coriell cell lines with documented CNVs, 184-gene virtual panel | 100% precision percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcecnv-20261009-protocol-delavega2025-coriell-virtual-panel Aggregation: Not reported Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications · Table 1, row '1' / '0.5–1', column 'Precision HS-F (%)' (exons spanned block) |
| Configuration: DRAGEN 4.2 high-sensitivity mode with custom artifact filters (HS-F) | Protocol: Coriell virtual gene-panel CNV precision by exon count and length (De La Vega et al. Table 1) Dataset: 25 Coriell cell lines with documented CNVs, 184-gene virtual panel | 81% precision percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcecnv-20261009-protocol-delavega2025-coriell-virtual-panel Aggregation: Not reported Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications · Table 1, row '2–5' / '1–10', column 'Precision HS-F (%)' (exons spanned block) |
| Configuration: DRAGEN 4.2 high-sensitivity mode with custom artifact filters (HS-F) | Protocol: Coriell virtual gene-panel CNV precision by exon count and length (De La Vega et al. Table 1) Dataset: 25 Coriell cell lines with documented CNVs, 184-gene virtual panel | 68% precision percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcecnv-20261009-protocol-delavega2025-coriell-virtual-panel Aggregation: Not reported Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications · Table 1, row '>5' / '>10', column 'Precision HS-F (%)' (exons spanned block) |
| Configuration: DRAGEN 4.2 high-sensitivity mode with custom artifact filters (HS-F) | Protocol: Coriell virtual gene-panel CNV precision by exon count and length (De La Vega et al. Table 1) Dataset: 25 Coriell cell lines with documented CNVs, 184-gene virtual panel | 100% precision percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcecnv-20261009-protocol-delavega2025-coriell-virtual-panel Aggregation: Not reported Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications · Table 1, row '1' / '0.5–1', column 'Precision HS-F (%)' (CNV length block) |
| Configuration: DRAGEN 4.2 high-sensitivity mode with custom artifact filters (HS-F) | Protocol: Coriell virtual gene-panel CNV precision by exon count and length (De La Vega et al. Table 1) Dataset: 25 Coriell cell lines with documented CNVs, 184-gene virtual panel | 89% precision percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcecnv-20261009-protocol-delavega2025-coriell-virtual-panel Aggregation: Not reported Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications · Table 1, row '2–5' / '1–10', column 'Precision HS-F (%)' (CNV length block) |
| Configuration: DRAGEN 4.2 high-sensitivity mode with custom artifact filters (HS-F) | Protocol: Coriell virtual gene-panel CNV precision by exon count and length (De La Vega et al. Table 1) Dataset: 25 Coriell cell lines with documented CNVs, 184-gene virtual panel | 74% precision percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcecnv-20261009-protocol-delavega2025-coriell-virtual-panel Aggregation: Not reported Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications · Table 1, row '>5' / '>10', column 'Precision HS-F (%)' (CNV length block) |
Source checking is not independent reproduction. Release 2026-10-09-9307685239b3.
cnv-20261009-protocol-delavega2025-coriell-virtual-panel
Metadata review: source checked. Unreported conditions prevent automatic comparisons.
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
19 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.comparison.adaptation Not reported Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | missing or unspecified No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.aggregation Pooled across cell lines, per stratum Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.budget Not reported Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | missing or unspecified No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.dataset_version Coriell annotations curated by authors Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.inputs 50x PCR-free WGS Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.metric_implementation Not reported Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | missing or unspecified No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.population Coding exons of 184 genes Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.protocol_id cnv-20261009-protocol-delavega2025-coriell-virtual-panel Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.split 25 cell lines Context-only references | Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
attributes.limitations1 values
| Benchmarking of germline copy number variant callers from whole genome sequencing data for clinical applications Table 1 Version: Bioinformatics Advances 5(1):vbaf071, published 2025-04-10; PMC12005901 full-text XML | not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-09-9307685239b3 · Record review: source checked
Stable ID: cnv-20261009-eval-delavega2025-dragen42-hs-filters-coriell-panel