UCSF respiratory RNA mNGS original-testing sensitivity; bounded primary-source candidate.
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1 evaluation · 1 result. Different protocols are not a single leaderboard.
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| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: UCSF respiratory RNA mNGS original-testing sensitivity tested configuration | Protocol: UCSF respiratory RNA mNGS original-testing sensitivity protocol Dataset: UCSF respiratory RNA mNGS original-testing sensitivity cohort | 93.6% (103 of 110) sensitivity_against_original_rvp_testing percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceUCSF respiratory RNA mNGS original-testing sensitivity amp-20261007-rna-pathogens-protocol Aggregation: Not reported Tan et al., Nature Communications 15, 9016 (2024) · PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. |
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amp-20261007-rna-pathogens-protocol
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20 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.comparison.adaptation Conventional sequence alignment pipeline; no foundation-model adaptation Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.aggregation Not reported Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.budget Not reported Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.dataset_version Not reported Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.inputs Respiratory RNA (DNase-treated), reverse-transcribed cDNA libraries; original clinical multiplex RT-PCR reference Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.metric_implementation sensitivity_against_original_rvp_testing Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.population 191 residual UCSF clinical samples: 110 RVP-virus-positive, 81 negative. Results says positive 104 upper respiratory swabs + 6 BAL; Methods instead 103 + 7, retained unresolved. Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.protocol_id amp-20261007-rna-pathogens-protocol Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.split Residual clinical accuracy cohort; no model training/test split reported Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.conventional_baseline Original clinical RVP assays: GenMark ePlex, Luminex NxTAG and/or Verigene RP Flex. Same cohort specificity 93.8% (76/81), accuracy 93.7% (179/191). DTCA agreements are separate endpoints and excluded. Context-only references | Tan et al., Nature Communications 15, 9016 (2024) PMC11558004 Results paragraph Par15; Table 1 Tab1 Accuracy / Original testing; Fig. 6A. Methods Par34 and Par38 define reference assays and mixed-target weighting. Version: Tan et al., Nature Communications 15, 9016 (2024) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
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Release 2026-10-07-1448159e6a81 · Record review: source checked
Stable ID: amp-20261007-rna-pathogens-evaluation