rewire.itbenchmarks
Dataset subset

mRNABench VEP (mRNABench split)

The split of mRNABench VEP that mRNABench evaluated on. The upstream dataset release is not catalogued here, so no claim is made that this matches its original splits.

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These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-09-29-06401fd5b220 · Evidence verified: Not verified

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Evaluation results

71 evaluations · 71 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: 3UTRBERTTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
31.2% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

3UTRBERT on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(3UTRBERT), column(VEP)
Configuration: AIDO.RNATask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
30.4% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AIDO.RNA on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(AIDO.RNA), column(VEP)
Configuration: DNABERT-STask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
30.6% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNABERT-S on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(DNABERT-S), column(VEP)
Configuration: DNABERT2Task: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
26.4% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DNABERT2 on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(DNABERT2), column(VEP)
Configuration: ERNIE-RNATask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
28.9% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ERNIE-RNA on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(ERNIE-RNA), column(VEP)
Configuration: Evo1Task: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
12% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Evo1 on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(Evo1), column(VEP)
Configuration: Evo2Task: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
32.1% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Evo2 on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(Evo2), column(VEP)
Configuration: Helix-mRNATask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
7.6% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Helix-mRNA on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(Helix-mRNA), column(VEP)
Configuration: HyenaDNATask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
23.2% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

HyenaDNA on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(HyenaDNA), column(VEP)
Method: Naive BaselineTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
19.5% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Naive Baseline on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(Naive Baseline), column(VEP)
Method: Naive MambaTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
10.2% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Naive Mamba on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(Naive Mamba), column(VEP)
Configuration: NTTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
31.8% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

NT on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(NT), column(VEP)
Configuration: OrthrusTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
27% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Orthrus on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(Orthrus), column(VEP)
Configuration: RiNALMoTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
31.6% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

RiNALMo on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(RiNALMo), column(VEP)
Configuration: RNA-FMTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
25.7% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

RNA-FM on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(RNA-FM), column(VEP)
Configuration: RNA-MSMTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
16.5% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

RNA-MSM on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(RNA-MSM), column(VEP)
Configuration: RNABERTTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
19.2% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

RNABERT on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(RNABERT), column(VEP)
Configuration: RNAErnieTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
17.3% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

RNAErnie on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(RNAErnie), column(VEP)
Configuration: SpliceBERTTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
28.2% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

SpliceBERT on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(SpliceBERT), column(VEP)
Method: Supervised CNNTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
33.2% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Supervised CNN on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(Supervised CNN), column(VEP)
Configuration: UTR-LMTask: mRNABench VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
21.3% auprc
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

UTR-LM on mRNABench VEP: Variant effect prediction

A linear probe over frozen embeddings, scored as the mean over ten random seeds.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 2, row(UTR-LM), column(VEP)
Pipeline: aido-rna-1b600m-cdsProtocol: mRNABench variant probes VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
0.304 ± 0.029 auprc
fraction · higher

Uncertainty: type: confidence_interval; confidence level: 0.95; reported half width: 0.029; aggregation: mean over ten random splits (table caption wording)

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

aido-rna-1b600m-cds on mRNABench variant probes VEP: Variant effect prediction

Frozen transcript representations with task-specific linear probes, or named supervised/naive controls. Homology splits where possible; random splits for MRL-MPRA, MRL-HL-Pair and VEP. Reported mean over ten splits; Appendix C enumerates nine seeds. Table captions say ten random splits, while Methods specify homology splits where possible. This source ambiguity and the nine explicitly listed seeds are retained; exact split manifests remain unextracted. Appendix C uses micro-averaged multilabel metrics.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 5 (XML T2), data row 2, XML tr 4, column 6 (VEP | AUPRC), model aido-rna-1b600m-cds
Pipeline: aido-rna-1b600mProtocol: mRNABench variant probes VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
0.316 ± 0.032 auprc
fraction · higher

Uncertainty: type: confidence_interval; confidence level: 0.95; reported half width: 0.032; aggregation: mean over ten random splits (table caption wording)

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

aido-rna-1b600m on mRNABench variant probes VEP: Variant effect prediction

Frozen transcript representations with task-specific linear probes, or named supervised/naive controls. Homology splits where possible; random splits for MRL-MPRA, MRL-HL-Pair and VEP. Reported mean over ten splits; Appendix C enumerates nine seeds. Table captions say ten random splits, while Methods specify homology splits where possible. This source ambiguity and the nine explicitly listed seeds are retained; exact split manifests remain unextracted. Appendix C uses micro-averaged multilabel metrics.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 5 (XML T2), data row 1, XML tr 3, column 6 (VEP | AUPRC), model aido-rna-1b600m
Pipeline: aido-rna-650m-cdsProtocol: mRNABench variant probes VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
0.312 ± 0.036 auprc
fraction · higher

Uncertainty: type: confidence_interval; confidence level: 0.95; reported half width: 0.036; aggregation: mean over ten random splits (table caption wording)

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

aido-rna-650m-cds on mRNABench variant probes VEP: Variant effect prediction

Frozen transcript representations with task-specific linear probes, or named supervised/naive controls. Homology splits where possible; random splits for MRL-MPRA, MRL-HL-Pair and VEP. Reported mean over ten splits; Appendix C enumerates nine seeds. Table captions say ten random splits, while Methods specify homology splits where possible. This source ambiguity and the nine explicitly listed seeds are retained; exact split manifests remain unextracted. Appendix C uses micro-averaged multilabel metrics.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 5 (XML T2), data row 4, XML tr 6, column 6 (VEP | AUPRC), model aido-rna-650m-cds
Pipeline: aido-rna-650mProtocol: mRNABench variant probes VEP: Variant effect prediction
Dataset subset: mRNABench VEP (mRNABench split)
0.309 ± 0.031 auprc
fraction · higher

Uncertainty: type: confidence_interval; confidence level: 0.95; reported half width: 0.031; aggregation: mean over ten random splits (table caption wording)

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

aido-rna-650m on mRNABench variant probes VEP: Variant effect prediction

Frozen transcript representations with task-specific linear probes, or named supervised/naive controls. Homology splits where possible; random splits for MRL-MPRA, MRL-HL-Pair and VEP. Reported mean over ten splits; Appendix C enumerates nine seeds. Table captions say ten random splits, while Methods specify homology splits where possible. This source ambiguity and the nine explicitly listed seeds are retained; exact split manifests remain unextracted. Appendix C uses micro-averaged multilabel metrics.

Aggregation: Not reported

mRNABench: A curated benchmark for mature mRNA property and function prediction · Table 5 (XML T2), data row 3, XML tr 5, column 6 (VEP | AUPRC), model aido-rna-650m

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

Subset and evaluation context

This record describes a particular subset or cohort used in an evaluation. Its results do not describe the full dataset.

Evidence

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Evidence table

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2 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
description
The split of mRNABench VEP that mRNABench evaluated on. The upstream dataset release is not catalogued here, so no claim is made that this matches its original splits.
Context-only references
mRNABench: A curated benchmark for mature mRNA property and function prediction

Original source ↗

No field-specific location recorded

Version: preprint archived 2025-07-08
Retrieved: 2026-09-16T10:41:16.497221+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 79f6264ee883535203c63a313547e7c57baa85585f76b42f8d899eb17fb7e600

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

name
mRNABench VEP (mRNABench split)
Context-only references
mRNABench: A curated benchmark for mature mRNA property and function prediction

Original source ↗

No field-specific location recorded

Version: preprint archived 2025-07-08
Retrieved: 2026-09-16T10:41:16.497221+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 79f6264ee883535203c63a313547e7c57baa85585f76b42f8d899eb17fb7e600

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

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Release 2026-09-29-06401fd5b220 · Record review: source checked

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Stable ID: mrnabench-dataset-mrnabench-vep

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