| Configuration: AlphaFold 3 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 5.49 irmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein af3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, iRMSD row, AlphaFold 3 column; Table 1 assessable count |
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| Configuration: AlphaFold 3 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 0.84 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein af3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, LDDT row, AlphaFold 3 column; Table 1 assessable count |
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| Configuration: AlphaFold 3 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 12.8 lrmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein af3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, lRMSD row, AlphaFold 3 column; Table 1 assessable count |
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| Configuration: AlphaFold 3 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 72.9% success-rate percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein af3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, Success rate row, AlphaFold 3 column; Table 1 assessable count |
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| Configuration: Boltz-1 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 6.63 irmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein boltz1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, iRMSD row, Boltz-1 column; Table 1 assessable count |
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| Configuration: Boltz-1 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 0.76 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein boltz1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, LDDT row, Boltz-1 column; Table 1 assessable count |
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| Configuration: Boltz-1 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 16.2 lrmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein boltz1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, lRMSD row, Boltz-1 column; Table 1 assessable count |
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| Configuration: Boltz-1 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 68.3% success-rate percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein boltz1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, Success rate row, Boltz-1 column; Table 1 assessable count |
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| Configuration: Chai-1 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 6.68 irmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein chai1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, iRMSD row, Chai-1 column; Table 1 assessable count |
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| Configuration: Chai-1 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 0.8 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein chai1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, LDDT row, Chai-1 column; Table 1 assessable count |
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| Configuration: Chai-1 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 15.2 lrmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein chai1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, lRMSD row, Chai-1 column; Table 1 assessable count |
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| Configuration: Chai-1 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 68.5% success-rate percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein chai1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, Success rate row, Chai-1 column; Table 1 assessable count |
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| Configuration: HelixFold 3 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 7.14 irmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein helixfold3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, iRMSD row, HelixFold 3 column; Table 1 assessable count |
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| Configuration: HelixFold 3 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 0.78 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein helixfold3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, LDDT row, HelixFold 3 column; Table 1 assessable count |
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| Configuration: HelixFold 3 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 16.5 lrmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein helixfold3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, lRMSD row, HelixFold 3 column; Table 1 assessable count |
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| Configuration: HelixFold 3 — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 66.3% success-rate percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein helixfold3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, Success rate row, HelixFold 3 column; Table 1 assessable count |
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| Configuration: Protenix — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 7.22 irmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein protenix Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, iRMSD row, Protenix column; Table 1 assessable count |
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| Configuration: Protenix — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 0.81 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein protenix Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, LDDT row, Protenix column; Table 1 assessable count |
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| Configuration: Protenix — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 17.5 lrmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein protenix Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, lRMSD row, Protenix column; Table 1 assessable count |
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| Configuration: Protenix — FoldBench published inference | Protocol: FoldBench protein-protein published full-set assessment Dataset: FoldBench protein-protein published targets | 68.2% success-rate percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein protein protenix Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-protein block, Success rate row, Protenix column; Table 1 assessable count |
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