| Configuration: AlphaFold 3 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.92 gdt-ts fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer af3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, GDT-TS row, AlphaFold 3 column; Table 1 assessable count |
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| Configuration: AlphaFold 3 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.88 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer af3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, LDDT row, AlphaFold 3 column; Table 1 assessable count |
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| Configuration: AlphaFold 3 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 1.95 rmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer af3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, RMSD row, AlphaFold 3 column; Table 1 assessable count |
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| Configuration: AlphaFold 3 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.94 tm-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer af3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, TM-score row, AlphaFold 3 column; Table 1 assessable count |
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| Configuration: Boltz-1 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.91 gdt-ts fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer boltz1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, GDT-TS row, Boltz-1 column; Table 1 assessable count |
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| Configuration: Boltz-1 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.87 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer boltz1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, LDDT row, Boltz-1 column; Table 1 assessable count |
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| Configuration: Boltz-1 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 1.97 rmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer boltz1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, RMSD row, Boltz-1 column; Table 1 assessable count |
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| Configuration: Boltz-1 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.94 tm-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer boltz1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, TM-score row, Boltz-1 column; Table 1 assessable count |
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| Configuration: Chai-1 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.9 gdt-ts fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer chai1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, GDT-TS row, Chai-1 column; Table 1 assessable count |
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| Configuration: Chai-1 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.87 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer chai1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, LDDT row, Chai-1 column; Table 1 assessable count |
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| Configuration: Chai-1 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 2.1 rmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer chai1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, RMSD row, Chai-1 column; Table 1 assessable count |
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| Configuration: Chai-1 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.93 tm-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer chai1 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, TM-score row, Chai-1 column; Table 1 assessable count |
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| Configuration: HelixFold 3 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.91 gdt-ts fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer helixfold3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, GDT-TS row, HelixFold 3 column; Table 1 assessable count |
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| Configuration: HelixFold 3 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.86 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer helixfold3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, LDDT row, HelixFold 3 column; Table 1 assessable count |
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| Configuration: HelixFold 3 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 2.03 rmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer helixfold3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, RMSD row, HelixFold 3 column; Table 1 assessable count |
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| Configuration: HelixFold 3 — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.94 tm-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer helixfold3 Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, TM-score row, HelixFold 3 column; Table 1 assessable count |
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| Configuration: Protenix — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.9 gdt-ts fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer protenix Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, GDT-TS row, Protenix column; Table 1 assessable count |
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| Configuration: Protenix — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.86 lddt fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer protenix Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, LDDT row, Protenix column; Table 1 assessable count |
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| Configuration: Protenix — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 2.04 rmsd angstrom · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer protenix Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, RMSD row, Protenix column; Table 1 assessable count |
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| Configuration: Protenix — FoldBench published inference | Protocol: FoldBench protein-monomer published full-set assessment Dataset: FoldBench protein-monomer published targets | 0.93 tm-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcefoldbench protein monomer protenix Not reported Aggregation: source table mean FoldBench supplementary target coverage and performance · Supplementary Table 3, protein-monomer block, TM-score row, Protenix column; Table 1 assessable count |
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