| Configuration: BERT2OME | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.795 ACC fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceBERT2OME: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC |
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| Configuration: 2OMe-LM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set |
0.963
AUPR fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and source2OMe-LM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 7: Human RNA 2OMe sites, independent test set AUPR |
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| Configuration: 2OMe-LM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set |
0.898
ACC fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and source2OMe-LM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC |
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| Configuration: H2Opred | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.8 F1-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceH2Opred: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 3: Human RNA 2OMe sites, independent test set F1-score |
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| Configuration: Meta-2OM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.881 AUPR fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceMeta-2OM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 7: Human RNA 2OMe sites, independent test set AUPR |
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| Configuration: NmRF | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.624 F1-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNmRF: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 3: Human RNA 2OMe sites, independent test set F1-score |
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| Configuration: Meta-2OM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.891 Precision fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceMeta-2OM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 4: Human RNA 2OMe sites, independent test set Precision |
|---|
| Configuration: NmRF | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.586 AUC fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNmRF: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 6: Human RNA 2OMe sites, independent test set AUC |
|---|
| Configuration: BERT2OME | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.813 Precision fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceBERT2OME: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 3 BERT2OME, column 4: Human RNA 2OMe sites, independent test set Precision |
|---|
| Configuration: NmRF | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.508 Precision fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNmRF: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 4: Human RNA 2OMe sites, independent test set Precision |
|---|
| Configuration: NmRF | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.512 ACC fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNmRF: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC |
|---|
| Configuration: Meta-2OM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.78 ACC fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceMeta-2OM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC |
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| Configuration: BERT2OME | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.788 F1-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceBERT2OME: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 3 BERT2OME, column 3: Human RNA 2OMe sites, independent test set F1-score |
|---|
| Configuration: 2OMe-LM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set |
0.952
AUC fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and source2OMe-LM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 6: Human RNA 2OMe sites, independent test set AUC |
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| Configuration: H2Opred | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.904 AUPR fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceH2Opred: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 7: Human RNA 2OMe sites, independent test set AUPR |
|---|
| Configuration: Meta-2OM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.639 Recall fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceMeta-2OM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 5: Human RNA 2OMe sites, independent test set Recall |
|---|
| Configuration: Meta-2OM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.584 MCC unitless · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceMeta-2OM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 5 Meta-2OM, column 8: Human RNA 2OMe sites, independent test set MCC |
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| Configuration: H2Opred | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.819 ACC fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceH2Opred: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC |
|---|
| Configuration: 2OMe-LM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.802 Recall fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and source2OMe-LM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 5: Human RNA 2OMe sites, independent test set Recall |
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| Configuration: H2Opred | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.89 Precision fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceH2Opred: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 4: Human RNA 2OMe sites, independent test set Precision |
|---|
| Configuration: 2OMe-LM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set |
0.887
F1-score fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and source2OMe-LM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 3: Human RNA 2OMe sites, independent test set F1-score |
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| Configuration: H2Opred | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.648 MCC unitless · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceH2Opred: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 4 H2Opred, column 8: Human RNA 2OMe sites, independent test set MCC |
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| Configuration: NmRF | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.03 MCC unitless · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNmRF: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 2 NmRF, column 8: Human RNA 2OMe sites, independent test set MCC |
|---|
| Configuration: 2OMe-LM | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set |
0.993
Precision fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and source2OMe-LM: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 6 2OMe-LM, column 4: Human RNA 2OMe sites, independent test set Precision |
|---|
| Configuration: BERT2OME | Protocol: Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction) Dataset: Human RNA 2OMe sites, independent test set | 0.878 AUC fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceBERT2OME: Human RNA 2OMe sites, independent test set 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set. Aggregation: Not reported 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Table 2. (btaf417-T2), row 3 BERT2OME, column 6: Human RNA 2OMe sites, independent test set AUC |
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