Human RNA 2OMe sites, independent test set (human RNA 2-prime-O-methylation site prediction)
Human RNA 2OMe sites, independent test set · ACC. 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.
Sources2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC
2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC
Do not pool cross-validation and independent-test scores. The 8:2 ratio is not converted into an exact test count. Training-data overlap for pre-existing predictors is not established by this table. Origins are labelled per method; appearance in one table does not constitute independent replication of every model.
Comparison details and limitations
41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.
Automated source review: 2026-09-17. Numerical source review does not establish independent reproduction.
Dots show point estimates. Whiskers show only explicitly defined uncertainty (standard deviation, standard error or a labelled interval); their definitions remain in Table. Unresolved uncertainty is not plotted. Differences do not establish statistical significance.
41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.
Sources2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model · Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC
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Explanatory profile: limited source coverage · Automated source review, 2026-09-17. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.
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Papers and result coverage
Last literature check: 2026-09-17. Dated primary-source discovery and protocol/table screening. Source checking does not mean experimental reproduction. Only separately extracted and independently reviewed numeric batches are publishable.
The catalogue now holds 35 result rows for this benchmark. A note below about pending extraction describes the state on 2026-09-17 and may since have been answered by a later batch. The result rows and their sources are the current record.
exact checkpoint hashes and per-method scored denominators: Table labels alone do not establish these fields; do not infer checkpoint or scored count from model name or dataset size.
Search and extraction details
complete tables extracted
Searches
2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model 10.1093/bioinformatics/btaf417
Evidence locations
Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC
Evidence table
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3 evidence rows matching the loaded filters
Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
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Evaluation in this paper
41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.
Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC
Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z
source checked
automated source review · 2026-09-17
Audit details
Primary-source transcription and separate automated review. No human sign-off or experimental reproduction.
Human RNA 2OMe sites, independent test set · ACC. 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.
Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC
Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z
source checked
automated source review · 2026-09-17
Audit details
Primary-source transcription and separate automated review. No human sign-off or experimental reproduction.
Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC
Version: journal full text in PMC Retrieved: 2026-09-16T10:33:38.332Z
41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.
comparison panels
id: 2ome-lm-2025-btaf417-t2-accuracy; title: Human RNA 2OMe sites, independent test set · ACC; protocol id: paper-protocol-d933438afda70a21ef; dataset id: paper-dataset-64b51e2f952f2c1c09; metric: ACC; unit: fraction; direction: higher; result ids: paper-result-6cd0c965571a51b666; paper-result-0a3793081d7daa05a3; paper-result-90076f457aae558dd0; paper-result-6f26b2a32012628065; paper-result-172c48ff6795f50b97; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC; context: 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.; caveats: Do not pool cross-validation and independent-test scores. The 8:2 ratio is not converted into an exact test count. Training-data overlap for pre-existing predictors is not established by this table. Origins are labelled per method; appearance in one table does not constitute independent replication of every model.; review: method: automated_source_review; date: 2026-09-17; id: 2ome-lm-2025-btaf417-t2-F1; title: Human RNA 2OMe sites, independent test set · F1-score; protocol id: paper-protocol-d933438afda70a21ef; dataset id: paper-dataset-64b51e2f952f2c1c09; metric: F1-score; unit: fraction; direction: higher; result ids: paper-result-2901879d63427fece0; paper-result-703d9f2e0a92c08138; paper-result-1f1eb13ac1d3b0659c; paper-result-d219017e57658f8194; paper-result-a6ed9c1d07e0a8e3ac; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 3: Human RNA 2OMe sites, independent test set F1-score; Table 2. (btaf417-T2), row 3 BERT2OME, column 3: Human RNA 2OMe sites, independent test set F1-score; Table 2. (btaf417-T2), row 4 H2Opred, column 3: Human RNA 2OMe sites, independent test set F1-score; Table 2. (btaf417-T2), row 5 Meta-2OM, column 3: Human RNA 2OMe sites, independent test set F1-score; Table 2. (btaf417-T2), row 6 2OMe-LM, column 3: Human RNA 2OMe sites, independent test set F1-score; context: 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.; caveats: Do not pool cross-validation and independent-test scores. The 8:2 ratio is not converted into an exact test count. Training-data overlap for pre-existing predictors is not established by this table. Origins are labelled per method; appearance in one table does not constitute independent replication of every model.; review: method: automated_source_review; date: 2026-09-17; id: 2ome-lm-2025-btaf417-t2-precision; title: Human RNA 2OMe sites, independent test set · Precision; protocol id: paper-protocol-d933438afda70a21ef; dataset id: paper-dataset-64b51e2f952f2c1c09; metric: Precision; unit: fraction; direction: higher; result ids: paper-result-657a6c49b38ef8252b; paper-result-6489236abf51572541; paper-result-a070ec6c349b5e96ef; paper-result-2d7677257f873b4e29; paper-result-b90e8cd12cecf6951f; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 4: Human RNA 2OMe sites, independent test set Precision; Table 2. (btaf417-T2), row 3 BERT2OME, column 4: Human RNA 2OMe sites, independent test set Precision; Table 2. (btaf417-T2), row 4 H2Opred, column 4: Human RNA 2OMe sites, independent test set Precision; Table 2. (btaf417-T2), row 5 Meta-2OM, column 4: Human RNA 2OMe sites, independent test set Precision; Table 2. (btaf417-T2), row 6 2OMe-LM, column 4: Human RNA 2OMe sites, independent test set Precision; context: 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.; caveats: Do not pool cross-validation and independent-test scores. The 8:2 ratio is not converted into an exact test count. Training-data overlap for pre-existing predictors is not established by this table. Origins are labelled per method; appearance in one table does not constitute independent replication of every model.; review: method: automated_source_review; date: 2026-09-17; id: 2ome-lm-2025-btaf417-t2-recall; title: Human RNA 2OMe sites, independent test set · Recall; protocol id: paper-protocol-d933438afda70a21ef; dataset id: paper-dataset-64b51e2f952f2c1c09; metric: Recall; unit: fraction; direction: higher; result ids: paper-result-eb25b223c10be4f330; paper-result-c8c5c199a2b0059317; paper-result-fab2a73ce6d700ff87; paper-result-7c85e27954addc7e14; paper-result-9980f6cb88d2219b02; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 5: Human RNA 2OMe sites, independent test set Recall; Table 2. (btaf417-T2), row 3 BERT2OME, column 5: Human RNA 2OMe sites, independent test set Recall; Table 2. (btaf417-T2), row 4 H2Opred, column 5: Human RNA 2OMe sites, independent test set Recall; Table 2. (btaf417-T2), row 5 Meta-2OM, column 5: Human RNA 2OMe sites, independent test set Recall; Table 2. (btaf417-T2), row 6 2OMe-LM, column 5: Human RNA 2OMe sites, independent test set Recall; context: 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.; caveats: Do not pool cross-validation and independent-test scores. The 8:2 ratio is not converted into an exact test count. Training-data overlap for pre-existing predictors is not established by this table. Origins are labelled per method; appearance in one table does not constitute independent replication of every model.; review: method: automated_source_review; date: 2026-09-17; id: 2ome-lm-2025-btaf417-t2-AUROC; title: Human RNA 2OMe sites, independent test set · AUC; protocol id: paper-protocol-d933438afda70a21ef; dataset id: paper-dataset-64b51e2f952f2c1c09; metric: AUC; unit: fraction; direction: higher; result ids: paper-result-48c539e46e8e0de49c; paper-result-c5e158015fb2c59552; paper-result-da8a9134bd3530143b; paper-result-ce07a0b8b72a4068f5; paper-result-76e7297a1974a4704a; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 6: Human RNA 2OMe sites, independent test set AUC; Table 2. (btaf417-T2), row 3 BERT2OME, column 6: Human RNA 2OMe sites, independent test set AUC; Table 2. (btaf417-T2), row 4 H2Opred, column 6: Human RNA 2OMe sites, independent test set AUC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 6: Human RNA 2OMe sites, independent test set AUC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 6: Human RNA 2OMe sites, independent test set AUC; context: 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.; caveats: Do not pool cross-validation and independent-test scores. The 8:2 ratio is not converted into an exact test count. Training-data overlap for pre-existing predictors is not established by this table. Origins are labelled per method; appearance in one table does not constitute independent replication of every model.; review: method: automated_source_review; date: 2026-09-17; id: 2ome-lm-2025-btaf417-t2-AUPRC; title: Human RNA 2OMe sites, independent test set · AUPR; protocol id: paper-protocol-d933438afda70a21ef; dataset id: paper-dataset-64b51e2f952f2c1c09; metric: AUPR; unit: fraction; direction: higher; result ids: paper-result-cf762cdb6f3083c1e5; paper-result-ea74464791a87509df; paper-result-79788c7d80922dad49; paper-result-209a40abae677db031; paper-result-13e1c3729d85f66b41; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 7: Human RNA 2OMe sites, independent test set AUPR; Table 2. (btaf417-T2), row 3 BERT2OME, column 7: Human RNA 2OMe sites, independent test set AUPR; Table 2. (btaf417-T2), row 4 H2Opred, column 7: Human RNA 2OMe sites, independent test set AUPR; Table 2. (btaf417-T2), row 5 Meta-2OM, column 7: Human RNA 2OMe sites, independent test set AUPR; Table 2. (btaf417-T2), row 6 2OMe-LM, column 7: Human RNA 2OMe sites, independent test set AUPR; context: 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.; caveats: Do not pool cross-validation and independent-test scores. The 8:2 ratio is not converted into an exact test count. Training-data overlap for pre-existing predictors is not established by this table. Origins are labelled per method; appearance in one table does not constitute independent replication of every model.; review: method: automated_source_review; date: 2026-09-17; id: 2ome-lm-2025-btaf417-t2-MCC; title: Human RNA 2OMe sites, independent test set · MCC; protocol id: paper-protocol-d933438afda70a21ef; dataset id: paper-dataset-64b51e2f952f2c1c09; metric: MCC; unit: unitless; direction: higher; result ids: paper-result-acad7ffaf81174cddb; paper-result-d947e45a8a87762a5f; paper-result-abe41dfecafe879c49; paper-result-85be9319f746a0dd77; paper-result-e68cc241f300063bca; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 8: Human RNA 2OMe sites, independent test set MCC; Table 2. (btaf417-T2), row 3 BERT2OME, column 8: Human RNA 2OMe sites, independent test set MCC; Table 2. (btaf417-T2), row 4 H2Opred, column 8: Human RNA 2OMe sites, independent test set MCC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 8: Human RNA 2OMe sites, independent test set MCC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 8: Human RNA 2OMe sites, independent test set MCC; context: 41-nt centred RNA windows; balanced 8,037 positive and 8,037 negative samples after 80% identity filtering, then 8:2 train/test division. Held-out independent test set.; caveats: Do not pool cross-validation and independent-test scores. The 8:2 ratio is not converted into an exact test count. Training-data overlap for pre-existing predictors is not established by this table. Origins are labelled per method; appearance in one table does not constitute independent replication of every model.; review: method: automated_source_review; date: 2026-09-17
benchmark research
review date: 2026-09-17; status: complete_tables_extracted; primary sources: 2ome-lm-2025; inspected locators: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC; searched queries: 2OMe-LM: predicting 2′-O-methylation sites in human RNA using a pre-trained RNA language model 10.1093/bioinformatics/btaf417; gaps: exact checkpoint hashes and per-method scored denominators: Table labels alone do not establish these fields; do not infer checkpoint or scored count from model name or dataset size.; claim scope: Dated primary-source discovery and protocol/table screening. Source checking does not mean experimental reproduction. Only separately extracted and independently reviewed numeric batches are publishable.
legacy kinds
benchmark
entity classification
review date: 2026-09-17; rationale: The source-backed record identifies a specified evaluated procedure and its dataset/split/scoring context. Classify it as a protocol while preserving version and comparison restrictions.; source ids: 2ome-lm-2025; source locator: Performance comparison of 2OMe-LM with existing predictors on the independent test set. a; Table 2. (btaf417-T2), row 2 NmRF, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 3 BERT2OME, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 4 H2Opred, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 5 Meta-2OM, column 2: Human RNA 2OMe sites, independent test set ACC; Table 2. (btaf417-T2), row 6 2OMe-LM, column 2: Human RNA 2OMe sites, independent test set ACC; ambiguities: None recorded