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Dataset

Pan_dataset five-fold PPI cross-validation

Dataset and cohort used in the cited comparison. Dataset population counts do not establish successful prediction coverage.

Evaluation results

3 evaluations · 15 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: ESM2_DPMProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.98 F1
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_DPM: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_DPM, column F1 Score; XML row4 column4
Configuration: ESM2_AMP_CSEProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.994 AUROC
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMP_CSE: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMP_CSE, column AUC; XML row3 column5
Configuration: ESM2_DPMProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.996 AUROC
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_DPM: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_DPM, column AUC; XML row4 column5
Configuration: ESM2_DPMProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.961 MCC
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_DPM: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_DPM, column MCC; XML row4 column6
Configuration: ESM2_AMP_CSEProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.974 Recall
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMP_CSE: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMP_CSE, column Recall; XML row3 column3
Configuration: ESM2_AMPSProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.995 AUROC
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMPS: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMPS, column AUC; XML row2 column5
Configuration: ESM2_AMPSProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.955 MCC
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMPS: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMPS, column MCC; XML row2 column6
Configuration: ESM2_AMP_CSEProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.957 MCC
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMP_CSE: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMP_CSE, column MCC; XML row3 column6
Configuration: ESM2_AMPSProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.978 Accuracy
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMPS: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMPS, column Accuracy; XML row2 column2
Configuration: ESM2_DPMProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.98 Accuracy
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_DPM: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_DPM, column Accuracy; XML row4 column2
Configuration: ESM2_AMP_CSEProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.979 F1
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMP_CSE: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMP_CSE, column F1 Score; XML row3 column4
Configuration: ESM2_AMP_CSEProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.979 Accuracy
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMP_CSE: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMP_CSE, column Accuracy; XML row3 column2
Configuration: ESM2_AMPSProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.978 F1
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMPS: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMPS, column F1 Score; XML row2 column4
Configuration: ESM2_AMPSProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.971 Recall
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_AMPS: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_AMPS, column Recall; XML row2 column3
Configuration: ESM2_DPMProtocol: Pan_dataset five-fold PPI cross-validation (protein-protein interaction prediction)
Dataset: Pan_dataset five-fold PPI cross-validation
0.974 Recall
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2_DPM: Pan_dataset five-fold PPI cross-validation

ESM 2_AMPS, ESM 2_AMP_CSE and ESM 2_DPM evaluated as complete PPI pipelines. Pan_dataset; Table 2 five-fold cross-validation.

Aggregation: Not reported

ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery · Table 2, row ESM2_DPM, column Recall; XML row4 column3

Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.

Research readiness

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Readiness checks, gaps and artifacts

Release 2026-11-02-a7f03c9e55a5 · Evidence verified: Not verified

Evidence incomplete

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  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

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Missing or unresolved evidence

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  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

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Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

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  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
  • Overlap with training data is checked: not yet verified

Verified: Not verified

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Dataset and evaluation context

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Evidence

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Evidence table

Inspect claims, sources and review details

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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

5 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statementOriginal source and locationReview and provenance
Source location
Table 2: Accuracy, Pan_dataset five-fold PPI cross-validation
Context-only references
ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery

Original source ↗

Table 2: Accuracy, Pan_dataset five-fold PPI cross-validation

Version: version of record
Retrieved: 2026-09-17T07:56:12.275470+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 8e7ad6efb72ca28d73037cdf465b0e62f99cd6d0ee4ca9eaf96a4c48da22fd6c

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Split
Pan_dataset; Table 2 five-fold cross-validation.
Context-only references
ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery

Original source ↗

Table 2: Accuracy, Pan_dataset five-fold PPI cross-validation

Version: version of record
Retrieved: 2026-09-17T07:56:12.275470+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.split

Source artifact SHA-256: 8e7ad6efb72ca28d73037cdf465b0e62f99cd6d0ee4ca9eaf96a4c48da22fd6c

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Subset
Pan_dataset five-fold PPI cross-validation
Context-only references
ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery

Original source ↗

Table 2: Accuracy, Pan_dataset five-fold PPI cross-validation

Version: version of record
Retrieved: 2026-09-17T07:56:12.275470+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.subset

Source artifact SHA-256: 8e7ad6efb72ca28d73037cdf465b0e62f99cd6d0ee4ca9eaf96a4c48da22fd6c

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Description
Dataset and cohort used in the cited comparison. Dataset population counts do not establish successful prediction coverage.
Context-only references
ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery

Original source ↗

Table 2: Accuracy, Pan_dataset five-fold PPI cross-validation

Version: version of record
Retrieved: 2026-09-17T07:56:12.275470+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 8e7ad6efb72ca28d73037cdf465b0e62f99cd6d0ee4ca9eaf96a4c48da22fd6c

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Name
Pan_dataset five-fold PPI cross-validation
Context-only references
ESM2_AMP: an interpretable framework for protein–protein interactions prediction and biological mechanism discovery

Original source ↗

Table 2: Accuracy, Pan_dataset five-fold PPI cross-validation

Version: version of record
Retrieved: 2026-09-17T07:56:12.275470+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 8e7ad6efb72ca28d73037cdf465b0e62f99cd6d0ee4ca9eaf96a4c48da22fd6c

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: needs review

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: paper-dataset-1de23e14845ef72241

areas
molecular-interactions
tasks
protein-protein interaction prediction
split
Pan_dataset; Table 2 five-fold cross-validation.
subset
Pan_dataset five-fold PPI cross-validation
source locator
Table 2: Accuracy, Pan_dataset five-fold PPI cross-validation
missing metadata
manifest: reason: unextracted; reported population: reason: unextracted; scored count: reason: unreported
entity classification
review date: 2026-09-17; rationale: This record identifies a biological data collection or source-labelled evaluation cohort. Keep its dataset identity; split, assay, taxonomic level, candidate restrictions and comparison context remain attributes rather than automatically becoming new entity kinds.; source ids: part2-esm2-amp-2025; source locator: Table 2: Accuracy, Pan_dataset five-fold PPI cross-validation; ambiguities: None recorded
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