| Configuration: NucleotideTransformer fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice acceptors and donors (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8826(0.0036) AUPRC (GTEx splicing task, Splice acceptors and donors, averaged over categories) fraction · higher Uncertainty: SD 0.0036 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNucleotideTransformer on the GTEx splicing task, Splice acceptors and donors gfm2-20261011-you2026-protocol-gtex-acceptors-donors Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice acceptors and donors', row 'NucleotideTransformer', column 'Average PR-AUC' |
|---|
| Configuration: RNAErnie fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice acceptors and donors (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8063(0.0015) AUPRC (GTEx splicing task, Splice acceptors and donors, averaged over categories) fraction · higher Uncertainty: SD 0.0015 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAErnie on the GTEx splicing task, Splice acceptors and donors gfm2-20261011-you2026-protocol-gtex-acceptors-donors Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice acceptors and donors', row 'RNAErnie', column 'Average PR-AUC' |
|---|
| Configuration: RNAFM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice acceptors and donors (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.7959(0.0011) AUPRC (GTEx splicing task, Splice acceptors and donors, averaged over categories) fraction · higher Uncertainty: SD 0.0011 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAFM on the GTEx splicing task, Splice acceptors and donors gfm2-20261011-you2026-protocol-gtex-acceptors-donors Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice acceptors and donors', row 'RNAFM', column 'Average PR-AUC' |
|---|
| Configuration: RNAMSM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice acceptors and donors (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8094(0.0010) AUPRC (GTEx splicing task, Splice acceptors and donors, averaged over categories) fraction · higher Uncertainty: SD 0.0010 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAMSM on the GTEx splicing task, Splice acceptors and donors gfm2-20261011-you2026-protocol-gtex-acceptors-donors Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice acceptors and donors', row 'RNAMSM', column 'Average PR-AUC' |
|---|
| Configuration: SpliceAI retrained under the authors' framework (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice acceptors and donors (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8622(0.0000) AUPRC (GTEx splicing task, Splice acceptors and donors, averaged over categories) fraction · higher Uncertainty: SD 0.0000 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpliceAI on the GTEx splicing task, Splice acceptors and donors gfm2-20261011-you2026-protocol-gtex-acceptors-donors Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice acceptors and donors', row 'SpliceAI', column 'Average PR-AUC' |
|---|
| Configuration: SpliceBERT fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice acceptors and donors (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8317(0.0096) AUPRC (GTEx splicing task, Splice acceptors and donors, averaged over categories) fraction · higher Uncertainty: SD 0.0096 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpliceBERT on the GTEx splicing task, Splice acceptors and donors gfm2-20261011-you2026-protocol-gtex-acceptors-donors Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice acceptors and donors', row 'SpliceBERT', column 'Average PR-AUC' |
|---|
| Configuration: SpTransformer retrained under the authors' framework (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice acceptors and donors (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8841(0.0018) AUPRC (GTEx splicing task, Splice acceptors and donors, averaged over categories) fraction · higher Uncertainty: SD 0.0018 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceSpTransformer on the GTEx splicing task, Splice acceptors and donors gfm2-20261011-you2026-protocol-gtex-acceptors-donors Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice acceptors and donors', row 'SpTransformer', column 'Average PR-AUC' |
|---|
| Configuration: UTRLM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice acceptors and donors (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8334(0.0000) AUPRC (GTEx splicing task, Splice acceptors and donors, averaged over categories) fraction · higher Uncertainty: SD 0.0000 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceUTRLM on the GTEx splicing task, Splice acceptors and donors gfm2-20261011-you2026-protocol-gtex-acceptors-donors Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice acceptors and donors', row 'UTRLM', column 'Average PR-AUC' |
|---|
| Configuration: NucleotideTransformer fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-15class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8646(0.0032) AUPRC (GTEx splicing task, Splice-15class, averaged over categories) fraction · higher Uncertainty: SD 0.0032 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNucleotideTransformer on the GTEx splicing task, Splice-15class gfm2-20261011-you2026-protocol-gtex-splice-15class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-15class', row 'NucleotideTransformer', column 'Average PR-AUC' |
|---|
| Configuration: RNAErnie fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-15class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.6868(0.0055) AUPRC (GTEx splicing task, Splice-15class, averaged over categories) fraction · higher Uncertainty: SD 0.0055 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAErnie on the GTEx splicing task, Splice-15class gfm2-20261011-you2026-protocol-gtex-splice-15class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-15class', row 'RNAErnie', column 'Average PR-AUC' |
|---|
| Configuration: RNAFM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-15class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.6770(0.0033) AUPRC (GTEx splicing task, Splice-15class, averaged over categories) fraction · higher Uncertainty: SD 0.0033 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAFM on the GTEx splicing task, Splice-15class gfm2-20261011-you2026-protocol-gtex-splice-15class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-15class', row 'RNAFM', column 'Average PR-AUC' |
|---|
| Configuration: RNAMSM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-15class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.6907(0.0044) AUPRC (GTEx splicing task, Splice-15class, averaged over categories) fraction · higher Uncertainty: SD 0.0044 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAMSM on the GTEx splicing task, Splice-15class gfm2-20261011-you2026-protocol-gtex-splice-15class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-15class', row 'RNAMSM', column 'Average PR-AUC' |
|---|
| Configuration: SpliceBERT fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-15class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.7538(0.0014) AUPRC (GTEx splicing task, Splice-15class, averaged over categories) fraction · higher Uncertainty: SD 0.0014 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpliceBERT on the GTEx splicing task, Splice-15class gfm2-20261011-you2026-protocol-gtex-splice-15class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-15class', row 'SpliceBERT', column 'Average PR-AUC' |
|---|
| Configuration: SpTransformer retrained under the authors' framework (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-15class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8568(0.0005) AUPRC (GTEx splicing task, Splice-15class, averaged over categories) fraction · higher Uncertainty: SD 0.0005 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceSpTransformer on the GTEx splicing task, Splice-15class gfm2-20261011-you2026-protocol-gtex-splice-15class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-15class', row 'SpTransformer', column 'Average PR-AUC' |
|---|
| Configuration: UTRLM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-15class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.7367(0.0000) AUPRC (GTEx splicing task, Splice-15class, averaged over categories) fraction · higher Uncertainty: SD 0.0000 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceUTRLM on the GTEx splicing task, Splice-15class gfm2-20261011-you2026-protocol-gtex-splice-15class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-15class', row 'UTRLM', column 'Average PR-AUC' |
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| Configuration: NucleotideTransformer fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-53class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8634(0.0004) AUPRC (GTEx splicing task, Splice-53class, averaged over categories) fraction · higher Uncertainty: SD 0.0004 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNucleotideTransformer on the GTEx splicing task, Splice-53class gfm2-20261011-you2026-protocol-gtex-splice-53class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-53class', row 'NucleotideTransformer', column 'Average PR-AUC' |
|---|
| Configuration: RNAErnie fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-53class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.6851(0.0182) AUPRC (GTEx splicing task, Splice-53class, averaged over categories) fraction · higher Uncertainty: SD 0.0182 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAErnie on the GTEx splicing task, Splice-53class gfm2-20261011-you2026-protocol-gtex-splice-53class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-53class', row 'RNAErnie', column 'Average PR-AUC' |
|---|
| Configuration: RNAFM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-53class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.6844(0.0035) AUPRC (GTEx splicing task, Splice-53class, averaged over categories) fraction · higher Uncertainty: SD 0.0035 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAFM on the GTEx splicing task, Splice-53class gfm2-20261011-you2026-protocol-gtex-splice-53class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-53class', row 'RNAFM', column 'Average PR-AUC' |
|---|
| Configuration: RNAMSM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-53class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.6955(0.0094) AUPRC (GTEx splicing task, Splice-53class, averaged over categories) fraction · higher Uncertainty: SD 0.0094 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceRNAMSM on the GTEx splicing task, Splice-53class gfm2-20261011-you2026-protocol-gtex-splice-53class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-53class', row 'RNAMSM', column 'Average PR-AUC' |
|---|
| Configuration: SpliceBERT fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-53class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.7387(0.0020) AUPRC (GTEx splicing task, Splice-53class, averaged over categories) fraction · higher Uncertainty: SD 0.0020 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpliceBERT on the GTEx splicing task, Splice-53class gfm2-20261011-you2026-protocol-gtex-splice-53class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-53class', row 'SpliceBERT', column 'Average PR-AUC' |
|---|
| Configuration: SpTransformer retrained under the authors' framework (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-53class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.8552(0.0053) AUPRC (GTEx splicing task, Splice-53class, averaged over categories) fraction · higher Uncertainty: SD 0.0053 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceSpTransformer on the GTEx splicing task, Splice-53class gfm2-20261011-you2026-protocol-gtex-splice-53class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-53class', row 'SpTransformer', column 'Average PR-AUC' |
|---|
| Configuration: UTRLM fine-tuned with an appended convolutional layer (You et al. 2026) | Protocol: GTEx tissue-specific splicing prediction, Splice-53class (You et al. 2026 Supplementary Table 5) Dataset: GTEx-derived tissue-specific splice site usage dataset (You et al. 2026) | 0.7244(0.0000) AUPRC (GTEx splicing task, Splice-53class, averaged over categories) fraction · higher Uncertainty: SD 0.0000 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceUTRLM on the GTEx splicing task, Splice-53class gfm2-20261011-you2026-protocol-gtex-splice-53class Aggregation: Not reported Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications; You et al. 2026, Supplementary Information · Supplementary Table 5, block 'Splice-53class', row 'UTRLM', column 'Average PR-AUC' |
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