| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 68% Accuracy percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'Accuracy (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 21 False negatives count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'FN' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 2 False positives count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'FP' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 0.24 MCC unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'MCC' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 5 Count (variants without a score) count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'Missing values' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 19% Negative predictive value percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'NPV (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 96% Precision percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'PPV (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 67% Recall percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'Sensitivity (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 71% Specificity percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'Specificity (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 5 True negatives count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'TN' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: ABCA4 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 3)
Dataset: ABCA4 noncanonical splice-site variants (Riepe et al. benchmark set) | 43 True positives count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on ABCA4 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-abca4-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 3 row 'Spidex', column 'TP' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 62% Accuracy percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'Accuracy (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 14 False negatives count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'FN' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 9 False positives count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'FP' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 0.25 MCC unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'MCC' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 3 Count (variants without a score) count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'Missing values' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 56% Negative predictive value percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'NPV (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 69% Precision percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'PPV (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 59% Recall percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'Sensitivity (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 67% Specificity percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'Specificity (%)' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 18 True negatives count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'TN' |
|---|
| Configuration: Spidex (Riepe et al. 2021) | Protocol: MYBPC3 noncanonical splice-site variants: classification against mini- or midigene splicing results (Riepe et al. Table 5)
Dataset: MYBPC3 noncanonical splice-site variants (Riepe et al. benchmark set) | 20 True positives count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceSpidex on MYBPC3 noncanonical splice-site variants splicing-follow-up-20261009-protocol-riepe2021-mybpc3-ncss Aggregation: Not reported Benchmarking deep learning splice prediction tools using functional splice assays · Table 5 row 'Spidex', column 'TP' |
|---|