SegmentEnformer-196kb
SegmentEnformer-196kb, scored on SegmentNT human genome annotation; its model version and settings are not identified.
Overview
An explanatory profile has not yet been reviewed for this record.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
14 evaluations · 28 results. Different protocols are not a single leaderboard.
Sorted by AUPRC (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
All 28 result rows with coverage, uncertainty and sources
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Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation 3UTR auPRC: 3UTR: per-nucleotide annotation (auPRC) Dataset subset: Human genome 3UTR test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.65 (± 0.051) AUPRC unitless · higher Uncertainty: SD 0.051 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 1; data row 19; model SegmentEnformer-196kb; column 3UTR |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation 3UTR MCC: 3UTR: per-nucleotide annotation (MCC) Dataset subset: Human genome 3UTR test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.68 (± 0.039) MCC unitless · higher Uncertainty: SD 0.039 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 1; data row 19; model SegmentEnformer-196kb; column 3UTR |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation 5UTR auPRC: 5UTR: per-nucleotide annotation (auPRC) Dataset subset: Human genome 5UTR test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.37 (± 0.020) AUPRC unitless · higher Uncertainty: SD 0.020 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 1; data row 19; model SegmentEnformer-196kb; column 5UTR |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation 5UTR MCC: 5UTR: per-nucleotide annotation (MCC) Dataset subset: Human genome 5UTR test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.44 (± 0.015) MCC unitless · higher Uncertainty: SD 0.015 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 1; data row 19; model SegmentEnformer-196kb; column 5UTR |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation CTCF-bound auPRC: CTCF-bound: per-nucleotide annotation (auPRC) Dataset subset: Human genome CTCF-bound test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.09 (± 0.008) AUPRC unitless · higher Uncertainty: SD 0.008 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 1; data row 19; model SegmentEnformer-196kb; column CTCF-bound |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation CTCF-bound MCC: CTCF-bound: per-nucleotide annotation (MCC) Dataset subset: Human genome CTCF-bound test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.19 (± 0.014) MCC unitless · higher Uncertainty: SD 0.014 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 1; data row 19; model SegmentEnformer-196kb; column CTCF-bound |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation enhancer tissue-invariant auPRC: enhancer tissue-invariant: per-nucleotide annotation (auPRC) Dataset subset: Human genome enhancer tissue-invariant test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.16 (± 0.020) AUPRC unitless · higher Uncertainty: SD 0.020 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 1; data row 19; model SegmentEnformer-196kb; column enhancer tissue-invariant |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation enhancer tissue-invariant MCC: enhancer tissue-invariant: per-nucleotide annotation (MCC) Dataset subset: Human genome enhancer tissue-invariant test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.28 (± 0.023) MCC unitless · higher Uncertainty: SD 0.023 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 1; data row 19; model SegmentEnformer-196kb; column enhancer tissue-invariant |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation enhancer tissue-specific auPRC: enhancer tissue-specific: per-nucleotide annotation (auPRC) Dataset subset: Human genome enhancer tissue-specific test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.45 (± 0.006) AUPRC unitless · higher Uncertainty: SD 0.006 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 1; data row 19; model SegmentEnformer-196kb; column enhancer tissue-specific |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation enhancer tissue-specific MCC: enhancer tissue-specific: per-nucleotide annotation (MCC) Dataset subset: Human genome enhancer tissue-specific test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.42 (± 0.005) MCC unitless · higher Uncertainty: SD 0.005 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 1; data row 19; model SegmentEnformer-196kb; column enhancer tissue-specific |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation exon auPRC: exon: per-nucleotide annotation (auPRC) Dataset subset: Human genome exon test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.50 (± 0.020) AUPRC unitless · higher Uncertainty: SD 0.020 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 1; data row 19; model SegmentEnformer-196kb; column exon |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation exon MCC: exon: per-nucleotide annotation (MCC) Dataset subset: Human genome exon test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.56 (± 0.015) MCC unitless · higher Uncertainty: SD 0.015 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 1; data row 19; model SegmentEnformer-196kb; column exon |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation intron auPRC: intron: per-nucleotide annotation (auPRC) Dataset subset: Human genome intron test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.88 (± 0.010) AUPRC unitless · higher Uncertainty: SD 0.010 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 1; data row 19; model SegmentEnformer-196kb; column intron |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation intron MCC: intron: per-nucleotide annotation (MCC) Dataset subset: Human genome intron test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.60 (± 0.017) MCC unitless · higher Uncertainty: SD 0.017 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 1; data row 19; model SegmentEnformer-196kb; column intron |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation lncRNA auPRC: lncRNA: per-nucleotide annotation (auPRC) Dataset subset: Human genome lncRNA test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.35 (± 0.017) AUPRC unitless · higher Uncertainty: SD 0.017 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 19; model SegmentEnformer-196kb; column lncRNA |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation lncRNA MCC: lncRNA: per-nucleotide annotation (MCC) Dataset subset: Human genome lncRNA test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.20 (± 0.025) MCC unitless · higher Uncertainty: SD 0.025 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 2; data row 19; model SegmentEnformer-196kb; column lncRNA |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation polyA signal auPRC: polyA signal: per-nucleotide annotation (auPRC) Dataset subset: Human genome polyA signal test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.02 (± 0.003) AUPRC unitless · higher Uncertainty: SD 0.003 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 19; model SegmentEnformer-196kb; column polyA signal |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation polyA signal MCC: polyA signal: per-nucleotide annotation (MCC) Dataset subset: Human genome polyA signal test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.01 (± 0.015) MCC unitless · higher Uncertainty: SD 0.015 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 2; data row 19; model SegmentEnformer-196kb; column polyA signal |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation promoter tissue-invariant auPRC: promoter tissue-invariant: per-nucleotide annotation (auPRC) Dataset subset: Human genome promoter tissue-invariant test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.55 (± 0.041) AUPRC unitless · higher Uncertainty: SD 0.041 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 19; model SegmentEnformer-196kb; column promoter tissue-invariant |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation promoter tissue-invariant MCC: promoter tissue-invariant: per-nucleotide annotation (MCC) Dataset subset: Human genome promoter tissue-invariant test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.59 (± 0.042) MCC unitless · higher Uncertainty: SD 0.042 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 2; data row 19; model SegmentEnformer-196kb; column promoter tissue-invariant |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation promoter tissue-specific auPRC: promoter tissue-specific: per-nucleotide annotation (auPRC) Dataset subset: Human genome promoter tissue-specific test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.17 (± 0.016) AUPRC unitless · higher Uncertainty: SD 0.016 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 19; model SegmentEnformer-196kb; column promoter tissue-specific |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation promoter tissue-specific MCC: promoter tissue-specific: per-nucleotide annotation (MCC) Dataset subset: Human genome promoter tissue-specific test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.26 (± 0.025) MCC unitless · higher Uncertainty: SD 0.025 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 2; data row 19; model SegmentEnformer-196kb; column promoter tissue-specific |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation protein coding gene auPRC: protein coding gene: per-nucleotide annotation (auPRC) Dataset subset: Human genome protein coding gene test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.93 (± 0.009) AUPRC unitless · higher Uncertainty: SD 0.009 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 19; model SegmentEnformer-196kb; column protein coding gene |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation protein coding gene MCC: protein coding gene: per-nucleotide annotation (MCC) Dataset subset: Human genome protein coding gene test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.83 (± 0.018) MCC unitless · higher Uncertainty: SD 0.018 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 2; PDF page 4 (printed 3); block 2; data row 19; model SegmentEnformer-196kb; column protein coding gene |
| Configuration: SegmentEnformer-196kb | Protocol: SegmentNT human genome annotation splice acceptor auPRC: splice acceptor: per-nucleotide annotation (auPRC) Dataset subset: Human genome splice acceptor test chromosomes 20 and 21 (SegmentNT human genome annotation split) | 0.02 (± 0.001) AUPRC unitless · higher Uncertainty: SD 0.001 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTest chromosomes 20 and 21; validation chromosome 22; training remaining chromosomes. Test chunks with genes homologous to train/validation genes excluded using Ensembl BioMart accessed 2024-05-08; homologous distal regulatory elements not excluded. Ten test-set samplings with sliding windows beginning at different genomic starting positions. Mean plus reported standard deviation; not ten training seeds. Best validation checkpoint by average MCC across 14 elements. Per-nucleotide predictions pooled across test sequences separately for each genomic element. MCC and auPRC are separate metrics, not cross-element or cross-table pooled comparisons. Aggregation: Not reported SegmentNT supplementary information: complete Tables 2 and 3 · Supplementary Table 3; PDF page 5 (printed 4); block 2; data row 19; model SegmentEnformer-196kb; column splice acceptor |
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Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
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- SegmentNT supplementary information: complete Tables 2 and 3 · Original source · Published supplementary information to s41592-025-02881-2; SHA-256 pinned snapshot
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Stable ID: segmentnt-supplement-2025-method-segmentenformer-196kb
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- Supplementary Tables 2 and 3 (PDF pages 4 and 5); primary article Methods / Model training and evaluation (Sec16), Model ablations and baselines (Sec17); row SegmentEnformer-196kb
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- Evaluated configuration as printed in Supplementary Tables 2 and 3; source reports training and checkpoint selection in Sec16–17.
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- system: SegmentEnformer-196kb on SegmentNT human genome annotation lncRNA auPRC: lncRNA: per-nucleotide annotation (auPRC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation lncRNA MCC: lncRNA: per-nucleotide annotation (MCC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation polyA signal auPRC: polyA signal: per-nucleotide annotation (auPRC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation polyA signal MCC: polyA signal: per-nucleotide annotation (MCC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation promoter tissue-invariant auPRC: promoter tissue-invariant: per-nucleotide annotation (auPRC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation promoter tissue-invariant MCC: promoter tissue-invariant: per-nucleotide annotation (MCC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation promoter tissue-specific auPRC: promoter tissue-specific: per-nucleotide annotation (auPRC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation promoter tissue-specific MCC: promoter tissue-specific: per-nucleotide annotation (MCC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation protein coding gene auPRC: protein coding gene: per-nucleotide annotation (auPRC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation protein coding gene MCC: protein coding gene: per-nucleotide annotation (MCC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation splice acceptor auPRC: splice acceptor: per-nucleotide annotation (auPRC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation splice acceptor MCC: splice acceptor: per-nucleotide annotation (MCC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation splice donor auPRC: splice donor: per-nucleotide annotation (auPRC)
- system: SegmentEnformer-196kb on SegmentNT human genome annotation splice donor MCC: splice donor: per-nucleotide annotation (MCC)