Pangolin scores released with the OpenSplice dataset (Jaganathan et al. 2026)
Pangolin scores released with the OpenSplice dataset: Exon-skipping predictions released with the OpenSplice MPRA dataset (reference 23); this paper did not rescore them and does not describe their settings.
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Evaluations and results
1 evaluation · 3 results. Different protocols are not a single leaderboard.
Protocol: OpenSplice MPRA delta PSI prediction for 283,121 single-nucleotide substitutions in 599 exons (SpliceAI2 paper, Spearman) · Dataset: OpenSplice MPRA single-nucleotide substitutions with measured delta PSI (as used by Jaganathan et al. 2026)
Sorted by Spearman (all variants; essential splice variants excluded) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | Spearman (all variants; essential splice variants excluded) | Spearman (exonic variants; essential splice variants excluded) | Spearman (intronic variants; essential splice variants excluded) |
|---|---|---|---|
| Pangolin scores released with the OpenSplice dataset (Jaganathan et al. 2026)Evaluation | 0.53 | 0.54 | 0.49 |
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Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
1 source record and release history
- A unified framework for quantitative splicing and transcript prediction (Jaganathan et al., bioRxiv 2026) · Original source · bioRxiv preprint version 1, posted 2026-10-11; full-text PDF (57 pages)
Technical metadata and extraction receipts
Stable ID: rna-splicing-20261013-spliceai2-config-pangolin-opensplice-released
- areas
- dna-genomes
- contexts
- research
- method types
- supervised_machine_learning
- foundation model eligible
- false
- reported name
- Pangolin
- parameters
- Exon-skipping predictions released with the OpenSplice MPRA dataset (reference 23); this paper did not rescore them and does not describe their settings
- source locator
- Methods 'Variant effect benchmarks', OpenSplice MPRA paragraph
- missing metadata
- version: reason: unreported; note: Settings are those of the OpenSplice release, not printed in this paper.
- provenance note
- Pangolin scores released with the OpenSplice dataset (Jaganathan et al. 2026), as evaluated in the SpliceAI2 paper.
Related records
- configuration of: Pangolin
- system: Pangolin on OpenSplice MPRA (spearman-correlation, SpliceAI2 paper)