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DPLM (650M)

Protein model evaluated by the ProteinBench authors under their harness.

20 evaluations · 20 results

Overview

Protein model evaluated by the ProteinBench authors under their harness.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

20 evaluations · 20 results. Different protocols are not a single leaderboard.

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Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-100-DIVERSITY-MAX-CLUST: length 100, Diversity Max Clust.
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.8 max-clust
score · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-100-DIVERSITY-MAX-CLUST: length 100, Diversity Max Clust.

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 100, Diversity Max Clust. ↑)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-100-DIVERSITY-PAIRWISE-TM: length 100, Diversity pairwise TM
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.50 ± 0.20 pairwise-tm
score · lower

Uncertainty: type: standard_deviation; value: 0.20

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-100-DIVERSITY-PAIRWISE-TM: length 100, Diversity pairwise TM

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 100, Diversity pairwise TM ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-100-NOVELTY-MAX-TM: length 100, Novelty Max TM
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.74 ± 0.10 max-tm
score · lower

Uncertainty: type: standard_deviation; value: 0.10

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-100-NOVELTY-MAX-TM: length 100, Novelty Max TM

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 100, Novelty Max TM ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-100-QUALITY-PLDDT: length 100, Quality pLDDT
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
85.38 ± 14.20 plddt
score · higher

Uncertainty: type: standard_deviation; value: 14.20

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-100-QUALITY-PLDDT: length 100, Quality pLDDT

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 100, Quality pLDDT ↑)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-100-QUALITY-PPL: length 100, Quality ppl
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
6.21 ± 3.10 ppl
score · lower

Uncertainty: type: standard_deviation; value: 3.10

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-100-QUALITY-PPL: length 100, Quality ppl

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 100, Quality ppl ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-200-DIVERSITY-MAX-CLUST: length 200, Diversity Max Clust.
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.7 max-clust
score · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-200-DIVERSITY-MAX-CLUST: length 200, Diversity Max Clust.

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 200, Diversity Max Clust. ↑)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-200-DIVERSITY-PAIRWISE-TM: length 200, Diversity pairwise TM
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.54 ± 0.24 pairwise-tm
score · lower

Uncertainty: type: standard_deviation; value: 0.24

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-200-DIVERSITY-PAIRWISE-TM: length 200, Diversity pairwise TM

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 200, Diversity pairwise TM ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-200-NOVELTY-MAX-TM: length 200, Novelty Max TM
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.91 ± 0.004 max-tm
score · lower

Uncertainty: type: standard_deviation; value: 0.004

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-200-NOVELTY-MAX-TM: length 200, Novelty Max TM

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 200, Novelty Max TM ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-200-QUALITY-PLDDT: length 200, Quality pLDDT
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
93.54 ± 3.73 plddt
score · higher

Uncertainty: type: standard_deviation; value: 3.73

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-200-QUALITY-PLDDT: length 200, Quality pLDDT

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 200, Quality pLDDT↑)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-200-QUALITY-PPL: length 200, Quality ppl
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
4.61 ± 2.63 ppl
score · lower

Uncertainty: type: standard_deviation; value: 2.63

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-200-QUALITY-PPL: length 200, Quality ppl

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 200, Quality ppl ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-300-DIVERSITY-MAX-CLUST: length 300, Diversity Max Clust.
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.63 max-clust
score · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-300-DIVERSITY-MAX-CLUST: length 300, Diversity Max Clust.

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 300, Diversity Max Clust. ↑)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-300-DIVERSITY-PAIRWISE-TM: length 300, Diversity pairwise TM
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.57 ± 0.25 pairwise-tm
score · lower

Uncertainty: type: standard_deviation; value: 0.25

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-300-DIVERSITY-PAIRWISE-TM: length 300, Diversity pairwise TM

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 300, Diversity pairwise TM ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-300-NOVELTY-MAX-TM: length 300, Novelty Max TM
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.91 ± 0.01 max-tm
score · lower

Uncertainty: type: standard_deviation; value: 0.01

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-300-NOVELTY-MAX-TM: length 300, Novelty Max TM

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 300, Novelty Max TM ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-300-QUALITY-PLDDT: length 300, Quality pLDDT
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
93.07 ± 5.77 plddt
score · higher

Uncertainty: type: standard_deviation; value: 5.77

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-300-QUALITY-PLDDT: length 300, Quality pLDDT

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 300, Quality pLDDT ↑)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-300-QUALITY-PPL: length 300, Quality ppl
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
3.47 ± 1.44 ppl
score · lower

Uncertainty: type: standard_deviation; value: 1.44

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-300-QUALITY-PPL: length 300, Quality ppl

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 300, Quality ppl ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-500-DIVERSITY-MAX-CLUST: length 500, Diversity Max Clust.
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.85 max-clust
score · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-500-DIVERSITY-MAX-CLUST: length 500, Diversity Max Clust.

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 500, Diversity Max Clust. ↑)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-500-DIVERSITY-PAIRWISE-TM: length 500, Diversity pairwise TM
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.43 ± 0.18 pairwise-tm
score · lower

Uncertainty: type: standard_deviation; value: 0.18

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-500-DIVERSITY-PAIRWISE-TM: length 500, Diversity pairwise TM

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 500, Diversity pairwise TM ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-500-NOVELTY-MAX-TM: length 500, Novelty Max TM
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
0.85 ± 0.04 max-tm
score · lower

Uncertainty: type: standard_deviation; value: 0.04

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-500-NOVELTY-MAX-TM: length 500, Novelty Max TM

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 500, Novelty Max TM ↓)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-500-QUALITY-PLDDT: length 500, Quality pLDDT
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
87.73 ± 11.61 plddt
score · higher

Uncertainty: type: standard_deviation; value: 11.61

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-500-QUALITY-PLDDT: length 500, Quality pLDDT

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 500, Quality pLDDT↑)
Configuration: DPLM (650M)Task: ProteinBench SEQ-LENGTH-500-QUALITY-PPL: length 500, Quality ppl
Dataset subset: Generated sequences at fixed lengths (ProteinBench split)
3.33 ± 1.8 ppl
score · lower

Uncertainty: type: standard_deviation; value: 1.8

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DPLM (650M) on ProteinBench SEQ-LENGTH-500-QUALITY-PPL: length 500, Quality ppl

Unconditional sequence generation at a fixed length. Values are the mean and standard deviation over repeated runs.

Aggregation: Not reported

proteinbench primary benchmark evidence · Table 4, row(DPLM (650M)), column(length 500, Quality ppl ↓)

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

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Release 2026-09-29-06401fd5b220 · Record review: source checked

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Stable ID: proteinbench-method-dplm-650m

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Table 4, row(DPLM (650M))
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