rewirebio.iobenchmarks
Configuration

Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)

DRAGEN column of Supplementary Table S3.

3 evaluations · 30 results

Overview

DRAGEN column of Supplementary Table S3.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

3 evaluations · 30 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
7.84 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12778', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
7.88 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12812', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
12.1 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12829', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
8.19 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12843', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
22.9 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12877', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
21.4 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12878', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
23.8 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12889', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
19.9 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12890', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
22 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12891', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
23.2 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-hc

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12892', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
14.1 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12778', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
12.4 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12812', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
21.7 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12829', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
15.3 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12843', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
41.1 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12877', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
38.9 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12878', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
43.2 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12889', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
36.2 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12890', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
40 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12891', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
42 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, read mapping stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-mapping

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12892', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025 Table S3c)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
21.9 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-total

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'c.) Total processing time: Read mapping & HC or DRAGEN GSVC', row 'NA12778', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025 Table S3c)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
20.3 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-total

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'c.) Total processing time: Read mapping & HC or DRAGEN GSVC', row 'NA12812', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025 Table S3c)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
33.8 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-total

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'c.) Total processing time: Read mapping & HC or DRAGEN GSVC', row 'NA12829', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025 Table S3c)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
23.4 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-total

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'c.) Total processing time: Read mapping & HC or DRAGEN GSVC', row 'NA12843', column 'DRAGEN' (PDF page text)
Configuration: Illumina DRAGEN v4.2 on DRAGEN server V2 (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025 Table S3c)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
64 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Illumina DRAGEN v4.2 on DRAGEN server V2, total of read mapping and HaplotypeCaller or DRAGEN GSVC (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-total

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'c.) Total processing time: Read mapping & HC or DRAGEN GSVC', row 'NA12877', column 'DRAGEN' (PDF page text)

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Stable ID: model-execution-20261009-config-samarakoon2025-dragen42-server-v2

areas
dna-genomes
contexts
clinical_research
method types
conventional_pipeline
foundation model eligible
false
reported name
DRAGEN
protocol
DRAGEN mapping, DRAGStr calibration and Germline Small Variant Caller (GSVC)
hardware
description: 2 Intel Xeon Gold 6126 (48 threads), 256 GB RAM, local NVMe SSD, CentOS 7
source locator
Supplementary Table S2; Methods 2.2-2.5; Table S3 column header
version
DRAGEN software v4.2
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