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Omni-DNA-300M (GENEB leaderboard)

Omni-DNA-300M: frozen embeddings; leaderboard display name 'Omni-DNA-300M'.

Overview

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Evaluations and results

3 evaluations · 45 results. Different protocols are not a single leaderboard.

Dataset: GENEB 100 tasks

Sorted by MCC (1-shot; category 'Chromatin Acc.') (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Protocol and dataset	MCC (1-shot; category 'Chromatin Acc.')	MCC (1-shot; category 'Coding/NC')	MCC (1-shot; category 'DNA Methyl.')	MCC (1-shot; category 'Enhancers')	MCC (1-shot; category 'Histone Mod.')	MCC (1-shot; category 'lncRNA')	MCC (1-shot; category 'Mouse Enh.')	MCC (1-shot; category 'Promoters')	MCC (1-shot; category 'Regulatory')	MCC (1-shot; category 'Species Clf.')	MCC (1-shot; category 'Splice Sites')	MCC (1-shot; category 'TF Binding')	MCC (1-shot; category 'Virus/Phage')	MCC (1-shot; macro average: unweighted mean of the 13 category MCCs)	MCC (1-shot; micro average: mean over all 100 tasks)	MCC (10-shot; category 'Chromatin Acc.')	MCC (10-shot; category 'Coding/NC')	MCC (10-shot; category 'DNA Methyl.')	MCC (10-shot; category 'Enhancers')	MCC (10-shot; category 'Histone Mod.')	MCC (10-shot; category 'lncRNA')	MCC (10-shot; category 'Mouse Enh.')	MCC (10-shot; category 'Promoters')	MCC (10-shot; category 'Regulatory')	MCC (10-shot; category 'Species Clf.')	MCC (10-shot; category 'Splice Sites')	MCC (10-shot; category 'TF Binding')	MCC (10-shot; category 'Virus/Phage')	MCC (10-shot; macro average: unweighted mean of the 13 category MCCs)	MCC (10-shot; micro average: mean over all 100 tasks)	MCC (full training data; category 'Chromatin Acc.')	MCC (full training data; category 'Coding/NC')	MCC (full training data; category 'DNA Methyl.')	MCC (full training data; category 'Enhancers')	MCC (full training data; category 'Histone Mod.')	MCC (full training data; category 'lncRNA')	MCC (full training data; category 'Mouse Enh.')	MCC (full training data; category 'Promoters')	MCC (full training data; category 'Regulatory')	MCC (full training data; category 'Species Clf.')	MCC (full training data; category 'Splice Sites')	MCC (full training data; category 'TF Binding')	MCC (full training data; category 'Virus/Phage')	MCC (full training data; macro average: unweighted mean of the 13 category MCCs)	MCC (full training data; micro average: mean over all 100 tasks)
Omni-DNA-300M (GENEB leaderboard)Evaluation	GENEB leaderboard, 1-shot, MCC aggregates	0.143	0.327	0.0216	0.163	0.119	0.0235	0.107	0.303	0.101	0.188	0.0836	0.142	0.024	0.134	0.15	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
Omni-DNA-300M (GENEB leaderboard)Evaluation	GENEB leaderboard, 10-shot, MCC aggregates	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	0.455	0.709	0.0517	0.342	0.278	0.063	0.199	0.531	0.155	0.427	0.218	0.257	0.125	0.293	0.304	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
Omni-DNA-300M (GENEB leaderboard)Evaluation	GENEB leaderboard, full training data, MCC aggregates	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	0.658	0.867	0.226	0.463	0.489	0.302	0.607	0.74	0.423	0.597	0.541	0.625	0.458	0.538	0.533

All 45 result rows with coverage, uncertainty and sources

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.455 MCC (10-shot; category 'Chromatin Acc.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Chromatin Acc.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.709 MCC (10-shot; category 'Coding/NC') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Coding/NC'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0517 MCC (10-shot; category 'DNA Methyl.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.DNA Methyl.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.342 MCC (10-shot; category 'Enhancers') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Enhancers'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.278 MCC (10-shot; category 'Histone Mod.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Histone Mod.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.063 MCC (10-shot; category 'lncRNA') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.lncRNA'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.293 MCC (10-shot; macro average: unweighted mean of the 13 category MCCs) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'macro_MCC'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.304 MCC (10-shot; micro average: mean over all 100 tasks) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'micro_MCC'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.199 MCC (10-shot; category 'Mouse Enh.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Mouse Enh.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.531 MCC (10-shot; category 'Promoters') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Promoters'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.155 MCC (10-shot; category 'Regulatory') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Regulatory'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.427 MCC (10-shot; category 'Species Clf.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Species Clf.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.218 MCC (10-shot; category 'Splice Sites') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Splice Sites'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.257 MCC (10-shot; category 'TF Binding') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.TF Binding'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.125 MCC (10-shot; category 'Virus/Phage') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'Omni-DNA-300M', key 'cat_MCC.Virus/Phage'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.143 MCC (1-shot; category 'Chromatin Acc.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'cat_MCC.Chromatin Acc.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.327 MCC (1-shot; category 'Coding/NC') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'cat_MCC.Coding/NC'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0216 MCC (1-shot; category 'DNA Methyl.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'cat_MCC.DNA Methyl.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.163 MCC (1-shot; category 'Enhancers') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'cat_MCC.Enhancers'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.119 MCC (1-shot; category 'Histone Mod.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'cat_MCC.Histone Mod.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0235 MCC (1-shot; category 'lncRNA') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'cat_MCC.lncRNA'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.134 MCC (1-shot; macro average: unweighted mean of the 13 category MCCs) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'macro_MCC'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.15 MCC (1-shot; micro average: mean over all 100 tasks) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'micro_MCC'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.107 MCC (1-shot; category 'Mouse Enh.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'cat_MCC.Mouse Enh.'
Configuration: Omni-DNA-300M (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.303 MCC (1-shot; category 'Promoters') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Omni-DNA-300M on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'Omni-DNA-300M', key 'cat_MCC.Promoters'

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GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · Original source · Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22)

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Technical metadata and extraction receipts

Stable ID: lit-genomics-20261011-geneb-config-omni-dna-300m

areas: dna-genomes
contexts: research
method types: foundation_model
reported name: Omni-DNA-300M
foundation model eligible: true
parameters: 300000000 parameters as listed; frozen embeddings; leaderboard display name 'Omni-DNA-300M'
access reuse: Public checkpoint as named on the leaderboard
version: Omni-DNA-300M
source locator: leaderboard.json data.full row model 'Omni-DNA-300M'
provenance note: Omni-DNA-300M as evaluated on the GENEB leaderboard.

Related records

configuration of: Omni-DNA
system: Omni-DNA-300M on GENEB (10-shot)
system: Omni-DNA-300M on GENEB (1-shot)
system: Omni-DNA-300M on GENEB (full training data)

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