Configuration

hyenadna-large-1m (GENEB leaderboard)

hyenadna-large-1m: hyenadna-large-1m-seqlen-hf; frozen embeddings; leaderboard display name 'hyenadna-large-1m'.

Overview

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Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

3 evaluations · 45 results. Different protocols are not a single leaderboard.

Dataset: GENEB 100 tasks

Sorted by MCC (1-shot; category 'Chromatin Acc.') (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Protocol and dataset	MCC (1-shot; category 'Chromatin Acc.')	MCC (1-shot; category 'Coding/NC')	MCC (1-shot; category 'DNA Methyl.')	MCC (1-shot; category 'Enhancers')	MCC (1-shot; category 'Histone Mod.')	MCC (1-shot; category 'lncRNA')	MCC (1-shot; category 'Mouse Enh.')	MCC (1-shot; category 'Promoters')	MCC (1-shot; category 'Regulatory')	MCC (1-shot; category 'Species Clf.')	MCC (1-shot; category 'Splice Sites')	MCC (1-shot; category 'TF Binding')	MCC (1-shot; category 'Virus/Phage')	MCC (1-shot; macro average: unweighted mean of the 13 category MCCs)	MCC (1-shot; micro average: mean over all 100 tasks)	MCC (10-shot; category 'Chromatin Acc.')	MCC (10-shot; category 'Coding/NC')	MCC (10-shot; category 'DNA Methyl.')	MCC (10-shot; category 'Enhancers')	MCC (10-shot; category 'Histone Mod.')	MCC (10-shot; category 'lncRNA')	MCC (10-shot; category 'Mouse Enh.')	MCC (10-shot; category 'Promoters')	MCC (10-shot; category 'Regulatory')	MCC (10-shot; category 'Species Clf.')	MCC (10-shot; category 'Splice Sites')	MCC (10-shot; category 'TF Binding')	MCC (10-shot; category 'Virus/Phage')	MCC (10-shot; macro average: unweighted mean of the 13 category MCCs)	MCC (10-shot; micro average: mean over all 100 tasks)	MCC (full training data; category 'Chromatin Acc.')	MCC (full training data; category 'Coding/NC')	MCC (full training data; category 'DNA Methyl.')	MCC (full training data; category 'Enhancers')	MCC (full training data; category 'Histone Mod.')	MCC (full training data; category 'lncRNA')	MCC (full training data; category 'Mouse Enh.')	MCC (full training data; category 'Promoters')	MCC (full training data; category 'Regulatory')	MCC (full training data; category 'Species Clf.')	MCC (full training data; category 'Splice Sites')	MCC (full training data; category 'TF Binding')	MCC (full training data; category 'Virus/Phage')	MCC (full training data; macro average: unweighted mean of the 13 category MCCs)	MCC (full training data; micro average: mean over all 100 tasks)
hyenadna-large-1m (GENEB leaderboard)Evaluation	GENEB leaderboard, 1-shot, MCC aggregates	0.129	0.311	0.00611	0.133	0.0859	0.0213	0.0165	0.272	0.0598	0.18	0.0644	0.0298	0.0421	0.104	0.117	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
hyenadna-large-1m (GENEB leaderboard)Evaluation	GENEB leaderboard, 10-shot, MCC aggregates	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	0.34	0.554	0.0554	0.264	0.198	0.0278	0.0433	0.462	0.142	0.385	0.125	0.0921	0.101	0.215	0.229	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
hyenadna-large-1m (GENEB leaderboard)Evaluation	GENEB leaderboard, full training data, MCC aggregates	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	0.54	0.712	0.169	0.436	0.448	0.158	0.39	0.696	0.423	0.666	0.401	0.532	0.346	0.455	0.468

All 45 result rows with coverage, uncertainty and sources

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Tested model or methodProtocolDatasetEvaluation setupMetricEvidence origin

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.34 MCC (10-shot; category 'Chromatin Acc.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Chromatin Acc.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.554 MCC (10-shot; category 'Coding/NC') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Coding/NC'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0554 MCC (10-shot; category 'DNA Methyl.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.DNA Methyl.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.264 MCC (10-shot; category 'Enhancers') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Enhancers'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.198 MCC (10-shot; category 'Histone Mod.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Histone Mod.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0278 MCC (10-shot; category 'lncRNA') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.lncRNA'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.215 MCC (10-shot; macro average: unweighted mean of the 13 category MCCs) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'macro_MCC'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.229 MCC (10-shot; micro average: mean over all 100 tasks) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'micro_MCC'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0433 MCC (10-shot; category 'Mouse Enh.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Mouse Enh.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.462 MCC (10-shot; category 'Promoters') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Promoters'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.142 MCC (10-shot; category 'Regulatory') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Regulatory'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.385 MCC (10-shot; category 'Species Clf.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Species Clf.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.125 MCC (10-shot; category 'Splice Sites') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Splice Sites'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0921 MCC (10-shot; category 'TF Binding') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.TF Binding'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 10-shot, MCC aggregates Dataset: GENEB 100 tasks	0.101 MCC (10-shot; category 'Virus/Phage') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (10-shot) lit-genomics-20261011-geneb-protocol-10shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.10shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Virus/Phage'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.129 MCC (1-shot; category 'Chromatin Acc.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Chromatin Acc.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.311 MCC (1-shot; category 'Coding/NC') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Coding/NC'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.00611 MCC (1-shot; category 'DNA Methyl.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.DNA Methyl.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.133 MCC (1-shot; category 'Enhancers') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Enhancers'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0859 MCC (1-shot; category 'Histone Mod.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Histone Mod.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0213 MCC (1-shot; category 'lncRNA') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.lncRNA'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.104 MCC (1-shot; macro average: unweighted mean of the 13 category MCCs) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'macro_MCC'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.117 MCC (1-shot; micro average: mean over all 100 tasks) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'micro_MCC'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.0165 MCC (1-shot; category 'Mouse Enh.') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Mouse Enh.'
Configuration: hyenadna-large-1m (GENEB leaderboard)	Protocol: GENEB leaderboard, 1-shot, MCC aggregates Dataset: GENEB 100 tasks	0.272 MCC (1-shot; category 'Promoters') unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source hyenadna-large-1m on GENEB (1-shot) lit-genomics-20261011-geneb-protocol-1shot Aggregation: Not reported GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · leaderboard.json data.1shot, model 'hyenadna-large-1m-seqlen-hf', key 'cat_MCC.Promoters'

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GENEB leaderboard (leaderboard.json, 13 task-type aggregates) · Original source · Git commit 9642d481e40c0af23995dcd162b779613f789f97 (repository pushed 2026-08-22)

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Technical metadata and extraction receipts

Stable ID: lit-genomics-20261011-geneb-config-hyenadna-large-1m-seqlen-hf

areas: dna-genomes
contexts: research
method types: foundation_model
reported name: hyenadna-large-1m-seqlen-hf
foundation model eligible: true
parameters: 54600000 parameters as listed; frozen embeddings; leaderboard display name 'hyenadna-large-1m'
access reuse: Public checkpoint as named on the leaderboard
version: hyenadna-large-1m-seqlen-hf
source locator: leaderboard.json data.full row model 'hyenadna-large-1m-seqlen-hf'
provenance note: hyenadna-large-1m-seqlen-hf as evaluated on the GENEB leaderboard.

Related records

configuration of: HyenaDNA
system: hyenadna-large-1m on GENEB (10-shot)
system: hyenadna-large-1m on GENEB (1-shot)
system: hyenadna-large-1m on GENEB (full training data)

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