ABC (DNALONGBENCH)
ABC: Expert model for ETGP: Activity-by-Contact model using DNase-seq, H3K27ac ChIP-seq and Hi-C inputs, not sequence only.
Overview
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Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
1 evaluation · 2 results. Different protocols are not a single leaderboard.
Protocol: DNALONGBENCH Enhancer-target gene prediction (Table 3) · Dataset: DNALONGBENCH Enhancer-target gene prediction test set
Sorted by AUPRC (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | AUPRC | AUROC |
|---|---|---|
| ABC (DNALONGBENCH)Evaluation | 0.407 | 0.926 |
All 2 result rows with coverage, uncertainty and sources
Filter evaluations
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: ABC (DNALONGBENCH) | Protocol: DNALONGBENCH Enhancer-target gene prediction (Table 3) Dataset: DNALONGBENCH Enhancer-target gene prediction test set | 0.407 AUPRC unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceExpert Model on DNALONGBENCH ETGP lit-genomics-20261011-dnalongbench-protocol-etgp Aggregation: Not reported DNALONGBENCH: a benchmark suite for long-range DNA prediction tasks · Table 3, row 'Expert Model', column 'AUPRC' |
| Configuration: ABC (DNALONGBENCH) | Protocol: DNALONGBENCH Enhancer-target gene prediction (Table 3) Dataset: DNALONGBENCH Enhancer-target gene prediction test set | 0.926 AUROC unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceExpert Model on DNALONGBENCH ETGP lit-genomics-20261011-dnalongbench-protocol-etgp Aggregation: Not reported DNALONGBENCH: a benchmark suite for long-range DNA prediction tasks · Table 3, row 'Expert Model', column 'AUROC' |
Source checking is not independent reproduction. Release 2026-10-23-5347695500ed.
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How it works, versions and access
Additional methodological details, versions and access terms have not yet been extracted into a structured profile for this configuration. Consult the linked sources and evaluation records below.
Evidence
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Evidence table
Inspect claims, sources and review details
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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
2 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
Facets: method types1 values
| DNALONGBENCH: a benchmark suite for long-range DNA prediction tasks DNALongBench Results: the expert model is ABC, "which incorporates DNase-seq, H3K27ac ChIP-seq data, and a Hi-C matrix"; MPRAbc Introduction: ABC is "a mathematical framework" combining activity and contact Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature Communications 16, published 2025-11-18; PMC12627797 full-text XML | conflicting claim ["source-hash-verification","automated-source-review"] · 2026-10-12 Audit detailsCorrect the method type from supervised_machine_learning to conventional_pipeline (use-case baseline review 2026-10-12, table 2). Evidence from docs/reviews/use-cases/baselines-2026-10-12.md. Independent review 2026-10-12: approved. DNALongBench does not say ABC has no training step; the locator was corrected to what the source prints, with MPRAbc for the form of the ABC score. See docs/reviews/2026-10-12-method-type-corrections.md. Conflicting source claim: Field: Claim: metadata-correction-tags-20261012-f8695fd337149b7221c4 Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record Extraction artifact SHA-256: |
Facets: method types1 values
| MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions DNALongBench Results: the expert model is ABC, "which incorporates DNase-seq, H3K27ac ChIP-seq data, and a Hi-C matrix"; MPRAbc Introduction: ABC is "a mathematical framework" combining activity and contact Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: PMC13232518 published article XML retrieved 2026-09-30 | conflicting claim ["source-hash-verification","automated-source-review"] · 2026-10-12 Audit detailsCorrect the method type from supervised_machine_learning to conventional_pipeline (use-case baseline review 2026-10-12, table 2). Evidence from docs/reviews/use-cases/baselines-2026-10-12.md. Independent review 2026-10-12: approved. DNALongBench does not say ABC has no training step; the locator was corrected to what the source prints, with MPRAbc for the form of the ABC score. See docs/reviews/2026-10-12-method-type-corrections.md. Conflicting source claim: Field: Claim: metadata-correction-tags-20261012-f8695fd337149b7221c4 Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record Extraction artifact SHA-256: |
Sources and history
Release 2026-10-23-5347695500ed · Record review: source checked
1 source record and release history
- DNALONGBENCH: a benchmark suite for long-range DNA prediction tasks · Original source · Nature Communications 16, published 2025-11-18; PMC12627797 full-text XML
Technical metadata and extraction receipts
Stable ID: lit-genomics-20261011-dnalongbench-config-abc
- areas
- dna-genomes
- contexts
- research
- method types
- conventional_pipeline
- reported name
- Expert Model (ABC)
- foundation model eligible
- false
- parameters
- Expert model for ETGP: Activity-by-Contact model using DNase-seq, H3K27ac ChIP-seq and Hi-C inputs, not sequence only
- access reuse
- Not stated in the main text
- source locator
- Methods 'Expert model', 'CNN' and 'DNA Foundation Model'
- missing metadata
- version: reason: unreported; note: Checkpoint or release not printed beyond the model name
- provenance note
- ABC as evaluated in DNALONGBENCH.
Related records
- configuration of: Activity-by-Contact (ABC)
- system: Expert Model on DNALONGBENCH ETGP
- subject: ABC (DNALONGBENCH): facets.method_types