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AMFR matched single-substitution pilot: plan and execution prerequisites

194a78b37eed911d0872e9b047a2539a9fee5dd0

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2 evidence claims
1 use case

Claims

Statements this source supports, each with where in the source it was checked.

Relevance of ProteinGym v1.3 AMFR seeded-random control to "Assess methods for protein stability experiments": Assessed by ProteinGym v1.3 AMFR seeded-random control (rewire-local-20260921-source-proteingym-random: /metrics; /coverage; /model_configuration; /protocol_configuration; /provenance; /protocol_results; rewire-local-20260921-instructions-proteingym-random: Pinned reproduction instructions and execution scope; use-case-source-amfr-pilot-plan-194a78b: Question; Task and data; Methods (N0); Analysis populations)
Relevance of ProteinGym v1.3 AMFR substitution assay to "Assess methods for protein stability experiments": Assessed by ProteinGym v1.3 AMFR substitution assay (rewire-local-20260920-source-proteingym-esm2: /metrics; /coverage; /execution/adapter_provenance; /execution; /input_information; /provenance; /protocol_results; rewire-local-20260920-instructions-proteingym: Data and method; Reproduce; profile-protocol-proteingym-reference-files-dms-substitutions-csv-a8f49801: AMFR_HUMAN_Tsuboyama_2023_4G3O row: seq_len, selection_assay, raw_DMS_phenotype_name and mutant-count columns; use-case-source-amfr-pilot-plan-194a78b: Question; Task and data; Methods; Gates and execution order; Runtime and cost)

Models, benchmarks and other records

Use cases (1)

Assess methods for protein stability experiments

Evidence

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Evidence table

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20 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statement	Original source and location	Review and provenance
Artifact SHA-256 a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43 Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.artifact_sha256` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Artifact url https://benchmarks.rewire.it/omics/sources/a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43.md Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.artifact_url` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Evidence origin rewire_documentation Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.evidence_origin` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Original artifact url https://raw.githubusercontent.com/rewire-bio/rewire-database/194a78b37eed911d0872e9b047a2539a9fee5dd0/docs/research/proteingym-amfr-pilot-2026-09-25/README.md Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.original_artifact_url` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Original url https://github.com/rewire-bio/rewire-database/blob/194a78b37eed911d0872e9b047a2539a9fee5dd0/docs/research/proteingym-amfr-pilot-2026-09-25/README.md Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.original_url` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Retrieval method Authenticated GitHub content API; exact bytes also compared with the pinned Git object. Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.retrieval_method` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Retrieved at 2026-09-25T15:28:11Z Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.retrieved_at` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Review artifact data/omics/use-cases/sources/amfr-pilot-readme.md Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.review_artifact` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Review method 1 values automated-source-review Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.review.method` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Review: scope Applicability interpretation and explicit evidence gaps; no numerical-result change or clinical validation. Source metadata	AMFR matched single-substitution pilot: plan and execution prerequisites Original source ↗ No field-specific location recorded Version: 194a78b37eed911d0872e9b047a2539a9fee5dd0 Retrieved: 2026-09-25T15:28:11Z	catalogued No individual claim review recorded Audit details Field: `attributes.review.scope` Source artifact SHA-256: `a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact

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Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

Pinned repository source for bounded use-case interpretation. Automated source review only; no new measurement, independent reproduction or human domain review.

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Technical metadata and extraction receipts

Stable ID: use-case-source-amfr-pilot-plan-194a78b

areas: proteins-complexes
url: https://benchmarks.rewire.it/omics/sources/a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43.md
artifact url: https://benchmarks.rewire.it/omics/sources/a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43.md
artifact sha256: a3208aa4537e8d28c56f68f4559299f31241c50b8d8b2b3776cba5f1718caa43
version: 194a78b37eed911d0872e9b047a2539a9fee5dd0
retrieved at: 2026-09-25T15:28:11Z
source type: rewire_protocol_documentation
evidence origin: rewire_documentation
review artifact: data/omics/use-cases/sources/amfr-pilot-readme.md
retrieval method: Authenticated GitHub content API; exact bytes also compared with the pinned Git object.
original url: https://github.com/rewire-bio/rewire-database/blob/194a78b37eed911d0872e9b047a2539a9fee5dd0/docs/research/proteingym-amfr-pilot-2026-09-25/README.md
original artifact url: https://raw.githubusercontent.com/rewire-bio/rewire-database/194a78b37eed911d0872e9b047a2539a9fee5dd0/docs/research/proteingym-amfr-pilot-2026-09-25/README.md
review: scope: Applicability interpretation and explicit evidence gaps; no numerical-result change or clinical validation.; method: automated-source-review

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