Source

Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants

Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 · Peer-reviewed

Original source

What this source contributed

Records in this release that cite this source. A record can cite several sources.

1 method
1 evidence claim

Claims

Statements this source supports, each with where in the source it was checked.

ClinPred: description: Description Scores missense variants by combining two machine-learning algorithms over existing pathogenicity scores and gnomAD population allele frequencies, trained on confidently annotated ClinVar variants. (qa-descriptions-20261011-e-source-clinpred: abstractText)

Models, benchmarks and other records

Methods (1)

ClinPred

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

26 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
attributes.artifact_sha256 63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63 Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.artifact_sha256` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Artifact url https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1016/j.ajhg.2018.08.005%22&format=json&resultType=core Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.artifact_url` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Hash scope SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.hash_scope` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Media type application/json Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.media_type` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Missing metadata: licence: note The retrieved record gives no licence Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.missing_metadata.licence.note` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Missing metadata: licence: reason unreported Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.missing_metadata.licence.reason` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Publication status peer_reviewed Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.publication_status` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Retrieved at 2026-10-11T01:38:37Z Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.retrieved_at` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Review: date 2026-10-11 Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.review.date` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Review: method note Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record. Source metadata	Abstract: ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide Variants Original source ↗ No field-specific location recorded Version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018 Retrieved: 2026-10-11T01:38:37Z	catalogued No individual claim review recorded Audit details Field: `attributes.review.method_note` Source artifact SHA-256: `63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

Source text retrieved and hashed for the issue #88 category-only description fix.

Release history

No supporting source is linked yet.

Read original source

Download this release (gzip)

Technical metadata and extraction receipts

Stable ID: qa-descriptions-20261011-e-source-clinpred

url: https://doi.org/10.1016/j.ajhg.2018.08.005
artifact url: https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1016/j.ajhg.2018.08.005%22&format=json&resultType=core
version: Europe PMC core record MED/30220433 (title and abstract), American Journal of Human Genetics 2018
retrieved at: 2026-10-11T01:38:37Z
artifact sha256: 63c0292fe97a07565c917ae562ca50bdb52f07a46d7052cfd66963026be63c63
publication status: peer_reviewed
media type: application/json
source locator: abstractText
hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence.
missing metadata: licence: reason: unreported; note: The retrieved record gives no licence
review: method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved with two corrections, both applied: the MutFormer source licence is CC BY 4.0 per the arXiv abstract page, and the MetaRNN source locator now names the Background passage. Checked the 27 Chen 2020 descriptions row by row against Table 1 (PMC7033911) and spot-checked AlphaMissense, MisFit, popEVE, VARITY, MetaRNN, MutFormer and gMVP against their abstracts; accurate. Licences on the other new sources match Europe PMC.; receipt: data/omics/qa-descriptions-20261011-e/review.json; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1016/j.ajhg.2018.08.005%22&format=json&resultType=core

Related records

Suggest a correction