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Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL)

Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 · Preprint

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ABYSSAL: description: Description ESM-2 network with an added light-attention mechanism, trained on the mega-scale stability dataset, which predicts the stability change on single mutation and satisfies the antisymmetry property. (qa-descriptions-20261011-d-source-abyssal: abstractText)

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ABYSSAL

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26 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
attributes.artifact_sha256 6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.artifact_sha256` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Artifact url https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1101/2022.12.31.522396%22&format=json&resultType=core Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.artifact_url` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Hash scope SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.hash_scope` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Media type application/json Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.media_type` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Missing metadata: licence: note The retrieved record gives no licence Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.missing_metadata.licence.note` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Missing metadata: licence: reason unreported Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.missing_metadata.licence.reason` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Publication status preprint Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.publication_status` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Retrieved at 2026-10-11T01:30:45Z Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.retrieved_at` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Review: date 2026-10-11 Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.review.date` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact
Review: method note Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record. Source metadata	Abstract: New mega dataset combined with deep neural network makes a progress in predicting impact of mutation on protein stability (ABYSSAL) Original source ↗ No field-specific location recorded Version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023 Retrieved: 2026-10-11T01:30:45Z	catalogued No individual claim review recorded Audit details Field: `attributes.review.method_note` Source artifact SHA-256: `6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf` Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence. Inspected artifact

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Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

Source text retrieved and hashed for the issue #88 category-only description fix.

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Stable ID: qa-descriptions-20261011-d-source-abyssal

url: https://doi.org/10.1101/2022.12.31.522396
artifact url: https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1101/2022.12.31.522396%22&format=json&resultType=core
version: Europe PMC preprint record PPR/PPR590902 (title and abstract), bioRxiv 2023
retrieved at: 2026-10-11T01:30:45Z
artifact sha256: 6b8741e12f40c5074150beecba35f0000e6d39a88c270d9327adfbcc57cddabf
publication status: preprint
media type: application/json
source locator: abstractText
hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. These responses are not byte-stable (a later retrieval can differ in JSON key order); the title and abstractText fields are the evidence.
missing metadata: licence: reason: unreported; note: The retrieved record gives no licence
review: method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved. Checked the 16 Pancotti-derived descriptions word for word against PMC8921618 section 2.2, ESM therm, RaSP and ELASPIC-2 against Chu 2024, ThermoMPNN against Dieckhaus 2024, and ABYSSAL and phyloP against their abstracts; all match. Licences on the new sources are supported by Europe PMC, the PMC XML and Crossref.; receipt: data/omics/qa-descriptions-20261011-d/review.json; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1101/2022.12.31.522396%22&format=json&resultType=core

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