AUROC (ProteinGym clinical substitutions, supervised clinical predictors, Average_AUC over proteins) of REVEL [ProteinGym 144fe22 clinical summary] on ProteinGym clinical substitution benchmark at commit 144fe22
0.928 AUROC (ProteinGym clinical substitutions, supervised clinical predictors, Average_AUC over proteins)
Methods
- Tested configuration
- REVEL [ProteinGym 144fe22 clinical summary]
- Protocol
- ProteinGym clinical substitutions, supervised predictors, average AUC (commit 144fe22)
- Dataset subset
- ProteinGym clinical substitution benchmark at commit 144fe22
- Procedure
- ProteinGym clinical substitutions, supervised predictors, average AUC (commit 144fe22)
- Evaluation
- REVEL: ProteinGym clinical substitutions, supervised predictors, average AUC (commit 144fe22)
- Coverage
- Not reported scored / Not reported eligible
- Uncertainty
- ± 0.003 (type not stated). Labelled a bootstrap standard error. The script that wrote the clinical summary was not read; in the DMS script the same column is the standard error of the difference from the top model, and the top row here prints 0.0, which suggests the same construction. Not verified for this file.
- Evidence
- Evaluation origin not reported · source checkedProteinGym clinical supervised substitutions AUC summary at commit 144fe22 · benchmarks/clinical_supervised/substitutions/AUC/Summary_performance_clinical_substitutions_AUC.csv line 6, row 'REVEL', column 'Average_AUC'
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.
Reproduction
- Split
- Not reported
- Adaptation
- Supervised clinical predictor scores from dbNSFP
- Scoring implementation
- Not reported
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 0.928 Individual claims | ProteinGym clinical supervised substitutions AUC summary at commit 144fe22 benchmarks/clinical_supervised/substitutions/AUC/Summary_performance_clinical_substitutions_AUC.csv line 6, row 'REVEL', column 'Average_AUC' Version: 144fe22b07dfaeec2b366f2346203a9838a55b4c | source checked ["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-14T15:30:00Z unreported Audit detailsExtracted by extract/extract_vep.py; independently re-checked by review/check_values.py. Value, metric and identity match the source. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record Extraction artifact SHA-256: |
Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
1 source record and release history
- ProteinGym clinical supervised substitutions AUC summary at commit 144fe22 · Original source · 144fe22b07dfaeec2b366f2346203a9838a55b4c
Technical metadata and extraction receipts
Stable ID: vep-lit-20261014-result-pg-css-proteingym-clinical-revel-average-auc
- metric
- auroc
- metric direction
- higher
- unit
- unitless
- metric qualifier
- ProteinGym clinical substitutions, supervised clinical predictors, Average_AUC over proteins
- printed value
- 0.928
- numeric value
- 0.928
- source locator
- benchmarks/clinical_supervised/substitutions/AUC/Summary_performance_clinical_substitutions_AUC.csv line 6, row 'REVEL', column 'Average_AUC'
- review
- reviewer: claude; reviewer note: Claude review agent; no human review claimed. Independent Claude (Opus 5.5) review agent, separate from the extraction agent that built this batch. Automated review only. Transcription, not reproduction.; reviewed at: 2026-10-14T15:30:00Z; artifact sha256: f2e38aeac2624d87e7a35a5b16bd580de62c24db36973848e1d94ac3ce510359; retrieval url: https://raw.githubusercontent.com/OATML-Markslab/ProteinGym/144fe22b07dfaeec2b366f2346203a9838a55b4c/benchmarks/clinical_supervised/substitutions/AUC/Summary_performance_clinical_substitutions_AUC.csv; method: source-hash-verification; deterministic-table-parse; independent-cell-check; method note: Re-downloaded the CSV from raw.githubusercontent.com at 144fe22 and matched the pinned SHA-256. review/check_values.py re-read it with the csv module and checked printed and numeric value, CSV line, Model_name, column, metric, qualifier, unit, direction, uncertainty and the linked configuration and protocol; all 1,794 ProteinGym results matched.; note: Extracted by extract/extract_vep.py; independently re-checked by review/check_values.py. Value, metric and identity match the source.
- uncertainty
- type: unresolved_spread; value: 0.003; printed: 0.003; source column: Bootstrap_standard_error_AUC; note: Labelled a bootstrap standard error. The script that wrote the clinical summary was not read; in the DMS script the same column is the standard error of the difference from the top model, and the top row here prints 0.0, which suggests the same construction. Not verified for this file.