rewirebio.iobenchmarks
Result

Accuracy (3-class (non-DE, up, down) accuracy within true |log2 FC| quantile Q5 (>0.116); quantile bins per cell line, averaged over four cell lines) of Perturbation majority vote (Sun et al. 2026) on K562, RPE1, HepG2 and Jurkat test sets (Sun et al. 2026)

84.1% Accuracy (3-class (non-DE, up, down) accuracy within true |log2 FC| quantile Q5 (>0.116); quantile bins per cell line, averaged over four cell lines)

Methods

Tested configuration
Perturbation majority vote (Sun et al. 2026)
Protocol
Sun et al. 2026 cellular-context DE classification (cross cell line)
Dataset subset
K562, RPE1, HepG2 and Jurkat test sets (Sun et al. 2026)
Procedure
Sun et al. 2026 cellular-context DE classification (cross cell line)
Evaluation
Majority vote on Sun et al. 2026 cross-cell-line DE classification, four cell lines
Coverage
Not reported scored / Not reported eligible
Uncertainty
Not reported by the source
Evidence
Author-reported evaluation · source checkedBeyond Expression Prediction: Benchmarking Differential Expression Classification in Single-Cell Perturbation Models · Table 4, row 'Majority vote', column 'Q5 (>0.116)'

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split
60/40 split by perturbation; held-out cell line
Adaptation
Trained per split
Scoring implementation
Wilcoxon rank-sum DE calls, BH-adjusted p < 0.01, on predicted and observed expression

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-10-23-5347695500ed
Property and statementOriginal source and locationReview and provenance
Reported result
84.08%
Individual claims
Beyond Expression Prediction: Benchmarking Differential Expression Classification in Single-Cell Perturbation Models

Original source ↗

Table 4, row 'Majority vote', column 'Q5 (>0.116)'

Version: bioRxiv preprint version 1, posted 2026-07-24
Retrieved: 2026-10-11T21:35:10Z

source checked

["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-12

author reported

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Extraction: Parsed the pdftotext -layout text of the pinned PDF with extract_sun2026.py: method rows matched by printed name with exactly five percentages, row order and column headers asserted. Table 4, row 'Majority vote', column 'Q5 (>0.116)'. Independent review 2026-10-12: value, locator, metric, unit, direction and linked configuration, protocol and dataset checked by the reviewer's own parse of all Tables 1-4 cells and a hand check of 48 values against the rendered pages. Corrections from the review applied by the extractor as listed in review.md.

Field: attributes.printed_value

Source artifact SHA-256: fa1c6a6345c45e14b9c373dfa8aff12633ae646feece1cfa3899c3ed61f6cfdf

Hash scope: Exact bytes of one download; bioRxiv serves slightly different PDF bytes per download, so the gzip copy in artifacts/ is the reference.

Inspected artifact

Extraction artifact SHA-256: fa1c6a6345c45e14b9c373dfa8aff12633ae646feece1cfa3899c3ed61f6cfdf

Extraction artifact

Sources and history

Release 2026-10-23-5347695500ed · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: lit-cells-networks-20261011-sun2026de-result-t4-cross-q5-majority-vote

metric
accuracy
metric direction
higher
unit
percent
printed value
84.08%
source locator
Table 4, row 'Majority vote', column 'Q5 (>0.116)'
review
method: source-hash-verification; deterministic-table-parse; independent-cell-check; method note: Parsed the pdftotext -layout text of the pinned PDF with extract_sun2026.py: method rows matched by printed name with exactly five percentages, row order and column headers asserted. Table 4, row 'Majority vote', column 'Q5 (>0.116)'; reviewer: claude; reviewer note: Claude review agent reviewer-cn-1, independent of the extractor lit-cells-networks; no human review claimed; date: 2026-10-12; artifact sha256: fa1c6a6345c45e14b9c373dfa8aff12633ae646feece1cfa3899c3ed61f6cfdf; retrieval url: https://www.biorxiv.org/content/10.64898/2026.07.20.739620v1.full.pdf; note: Extraction: Parsed the pdftotext -layout text of the pinned PDF with extract_sun2026.py: method rows matched by printed name with exactly five percentages, row order and column headers asserted. Table 4, row 'Majority vote', column 'Q5 (>0.116)'. Independent review 2026-10-12: value, locator, metric, unit, direction and linked configuration, protocol and dataset checked by the reviewer's own parse of all Tables 1-4 cells and a hand check of 48 values against the rendered pages. Corrections from the review applied by the extractor as listed in review.md.
numeric value
84.08
metric qualifier
3-class (non-DE, up, down) accuracy within true |log2 FC| quantile Q5 (>0.116); quantile bins per cell line, averaged over four cell lines
missing metadata
uncertainty: reason: unreported
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