Chirality consistency of Boltz Rc on Plinder-L95
100% Chirality consistency
Methods
- Tested configuration
- Boltz Rc
- Protocol
- Paper-specific Plinder-L95 stereochemistry assessment; Table 1 all entries · Plinder-L95 · co-folding
- Dataset subset
- Plinder-L95
- Related family profiles
- Boltz
- Procedure
- Paper-specific Plinder-L95 stereochemistry assessment; Table 1 all entries
- Evaluation
- Boltz Rc · Paper-specific Plinder-L95 stereochemistry assessment; Table 1 all entries · Plinder-L95
- Coverage
- Not reported scored / Not reported eligible
- Uncertainty
- Not yet extracted
- Evidence
- Author-reported evaluation · source checkedImproving Stereochemical Limitations in Protein–Ligand Complex Structure Prediction · Table 1 (XML tbl1); row Boltz Rc; column chirality; footnote a
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: discovered. Source checked does not mean independently reproduced.
Reproduction
- Split
- all entries (includes Before and After training cutoff subsets)
- Adaptation
- unreported
- Scoring implementation
- Not reported
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 100 Individual claims | Improving Stereochemical Limitations in Protein–Ligand Complex Structure Prediction Table 1 (XML tbl1); row Boltz Rc; column chirality; footnote a Version: version of record | source checked ["independent-cell-check","scope-review"] · 2026-09-19 author reported Audit detailsTranscription checked independently. No human review or scientific reproduction claimed. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record Extraction artifact SHA-256: |
Sources and history
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
1 source record and release history
- Improving Stereochemical Limitations in Protein–Ligand Complex Structure Prediction · Original source · version of record
Technical metadata and extraction receipts
Stable ID: acquired-result-e9a8c102cf9958f136c2
- metric
- chirality-consistency
- metric direction
- higher
- unit
- percent
- printed value
- 100
- numeric value
- 100
- aggregation
- percentage of molecules with consistent chirality
- scoring conditions
- aggregation: percentage of molecules with consistent chirality; checkpoint hash: Not reported; comparison compatibility: mixed_input_information; descriptive source table only, no ranked fair-comparison claim; dataset size: 6600; eligible count: Not reported; input information: Vina receives ground-truth ligand-centred 30 angstrom cubic search box and exhaustiveness 16; neural co-folding methods receive shared MMSeqs2 v15 MSAs; input conditions differ.; model configuration: Boltz recycle=10, diffusion samples=5; AF3 and DiffDock default parameters; restraint variants as table condition.; plinder release: unextracted; restraint parameters: σstart = 1, w chiral = 1, w geom = 0; scored count: Not reported; selection: monomer proteins; single nonpolymeric ligand with sp3-carbon chiral center; allowed elements C,N,O,F,P,S,Cl,Br,I; RDKit conformer generation; ligand Tanimoto clustering 0.95; training overlap: All-entry summary includes structures before 2021-09-30; do not label held-out generalization.
- source locator
- Table 1 (XML tbl1); row Boltz Rc; column chirality; footnote a
- missing metadata
- denominator: reason: unreported; uncertainty: reason: unextracted
- review
- method: independent-cell-check; scope-review; date: 2026-09-19; artifact sha256: 78a77b9a0ab8bfa371f5b9baef3f443f4590d6e71cf864d67e90e9ebdfa7fc1b; receipt: data/omics/acquisition/2026-09-19/proteins/; method note: cell check automated and independent; scope review AI-assisted; note: Transcription checked independently. No human review or scientific reproduction claimed.